Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A

Preferred Label : Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A;

NCIt synonyms : EC 5.2.1.8; Calstabin-1; Rotamase; FK506-Binding Protein 1A; Protein Kinase C Inhibitor 2; 12 kDa FK506-Binding Protein; FKBP-1A; Immunophilin FKBP12; FKBP-12; 12 kDa FKBP; PPIase FKBP1A; FKBP1A; Calstabin1; FKBP Prolyl Isomerase 1A; Calstabin 1;

NCIt definition : Peptidyl-prolyl cis-trans isomerase FKBP1A (108 aa, 12 kDa) is encoded by the human FKBP1A gene. This protein is involved in both protein folding and the modulation of TGF-beta signaling.;

Details

Origin ID

C102485;

UMLS CUI

C2934980;

OMIM relation
- Fk506-binding protein 1a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- FKBP1A protein, human [MeSH concept]
- FKBP1A protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- FKBP1A Gene [NCIt concept]
- Isomerase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_chemical_classification
- FK506 Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
- Calcineurin-Dependent NFAT Signaling Pathway in Lymphocytes [NCIt concept]
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- TGF-Beta Receptor Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway BioCarta [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein Folding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Encapsulated Rapamycin [NCIt concept]
- Everolimus [NCIt concept]
- Sirolimus [NCIt concept]
- Sirolimus Albumin-bound Nanoparticles [NCIt concept]
- Sirolimus Topical Gel NPC-12Y [NCIt concept]
- Sirolimus Topical Gel PTX-022 [NCIt concept]

Keyword's position in hierarchy(ies) :

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