Protein O-Mannosyl-Transferase 2

Preferred Label : Protein O-Mannosyl-Transferase 2;

NCIt synonyms : POMT2; Protein O-Mannosyltransferase 2; Dolichyl-Phosphate-Mannose-Protein Mannosyltransferase 2; Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 2; EC 2.4.1.109;

NCIt definition : Protein O-mannosyl-transferase 2 (750 aa, 84 kDa) is encoded by the human POMT2 gene. This protein plays a role in the O-mannosylation of serine or threonine residues.;

NCIt note : Coexpression of protein O-mannosyl-transferase (POMT) 1 and POMT2 is necessary for enzyme activity.;

Details

Origin ID

C204535;

UMLS CUI

C1433243;

OMIM relation
- Protein o-mannosyltransferase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- POMT2 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- POMT2 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- O-Mannosyl Glycan Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Protein Glycosylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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