Cone cGMP-Specific 3',5'-Cyclic Phosphodiesterase Subunit Alpha'

Preferred Label : Cone cGMP-Specific 3',5'-Cyclic Phosphodiesterase Subunit Alpha';

NCIt synonyms : EC 3.1.4.35; PDE6C; Cone cGMP-Specific 3',5'-Cyclic Phosphodiesterase Alpha Prime Subunit; Cone cGMP-Specific 3',5'-Cyclic Phosphodiesterase Subunit Alpha Prime; cGMP Phosphodiesterase 6C;

NCIt definition : Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (858 aa, 99 kDa) is encoded by the human PDE6C gene. This protein plays a role in the reversible conversion of cyclic guanosine monophosphate into guanosine monophosphate.;

NCIt note : Cone phosphodiesterase includes a homodimer of two cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' moieties that is associated with 3 smaller proteins of 11, 13, and 15 kDa.;

Details

Origin ID

C204196;

UMLS CUI

C0384146;

OMIM relation
- Phosphodiesterase 6c [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PDE6C protein, human [MeSH Supplementary Concept]
- PDE6C protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PDE6C Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cone Cell Visual Signal Transduction Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Color Vision [NCIt concept]
- Hydrolysis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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