S-Adenosylmethionine Decarboxylase Proenzyme

Preferred Label : S-Adenosylmethionine Decarboxylase Proenzyme;

NCIt synonyms : AdoMetDC; SAMDC; EC 4.1.1.50; S-Adenosylmethionine Decarboxylase 1; S-Adenosyl-L-Methionine Carboxy-Lyase; AMD1; S-Adenosyl-L-Methionine Decarboxylase; S-Adenosyl-Methionine Decarboxylase;

NCIt definition : S-adenosylmethionine decarboxylase proenzyme (334 aa, 38 kDa) is encoded by the human AMD1 gene. This protein is involved in polyamine metabolism.;

NCIt note : The active site pyruvoyl group for S-adenosylmethionine decarboxylase is generated from an internal serine residue via an autocatalytic post-translational modification. (UniProt);

Details

Origin ID

C102775;

UMLS CUI

C4278213;

OMIM relation
- S-adenosylmethionine decarboxylase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- AMD1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- AMD1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Lyase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arginine and Proline Metabolism Pathway [NCIt concept]
- Cysteine and Methionine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biogenic Amine Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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