Ribonucleoside-Diphosphate Reductase Large Subunit

Preferred Label : Ribonucleoside-Diphosphate Reductase Large Subunit;

NCIt synonyms : Ribonucleotide Reductase Large Chain; RRM1 Protein; Ribonucleotide Reductase M1 Polypeptide; RRM1; Ribonucleotide Reductase R1 Subunit; Ribonucleotide Reductase Large Subunit; Ribonucleoside-Diphosphate Reductase Subunit M1; Ribonucleoside-Diphosphate Reductase-M1 Chain; EC 1.17.4.1; Ribonucleoside-Diphosphate Reductase M1 Chain;

NCIt definition : Ribonucleoside-diphosphate reductase large subunit (792 aa, 90 kDa) is encoded by the human RRM1 gene. This protein is involved in the conversion of ribonucleotides to deoxyribonucleotides.;

Details

Origin ID

C21213;

UMLS CUI

C1259395;

Automatic exact mappings (from CISMeF team)
- Ribonucleotide reductase catalytic subunit m1 [OMIM gene]
OMIM relation
- Ribonucleotide reductase catalytic subunit m1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RRM1 protein, human [MeSH concept]
- RRM1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- RRM1 Gene [NCIt concept]
- Ribonucleotide Reductase Subunit Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_chemical_classification
- Ribonucleotide Reductase Subunit [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- E2F Transcription Factor Pathway [NCIt concept]
- Glutathione Metabolism Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ribonucleotide Reductase [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- DNA Replication [NCIt concept]
- DNA Synthesis [NCIt concept]
- Metastasis Suppression [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- RNA Synthesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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