85 kDa Calcium-Independent Phospholipase A2

Preferred Label : 85 kDa Calcium-Independent Phospholipase A2;

NCIt synonyms : Calcium-Independent Phospholipase A2; Calcium-Independent Cytosolic Phospholipase A2VI; Phospholipase A2 Group VI; iPLA2; Calcium-Independent Cytosolic Phospholipase A2 Group VI; CaI-PLA2; Group VI Phospholipase A2; Phospholipase A2VI; Cytosolic Phospholipase-A2G6; PLA2G6; GVI PLA2; Calcium-Independent Cytosolic Phospholipase A2; EC 3.1.1.4; Cytosolic Phospholipase A2G6;

NCIt definition : 85 kDa calcium-independent phospholipase A2 (806 aa, 90 kDa) is encoded by the human PLA2G6 gene. This protein is involved in the hydrolysis of glycerophospholipids.;

Details

Origin ID

C38598;

UMLS CUI

C0538273;

Currated CISMeF NLP mapping
- group VI phospholipases A2 [MeSH Descriptor]
- group VI phospholipases A2 [MeSH concept]
- phospholipases A2, Calcium-Independent [MeSH concept]
- phospholipases a2, calcium-independent [MeSH Descriptor]
OMIM relation
- Phospholipase a2, group VI [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PLA2G6 protein, human [MeSH Supplementary Concept]
- PLA2G6 protein, human [MeSH concept]
- group VI phospholipases A2 [MeSH concept]
- group VI phospholipases A2 [MeSH Descriptor]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PLA2G6 Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
- Lipase [NCIt concept]
- Phospholipase A2 Enzyme Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arachidonic Acid Metabolism Pathway [NCIt concept]
- Ether Lipid Metabolism Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Glycerophospholipid Metabolism Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Linoleic Acid Metabolism Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Prostaglandin and Leukotriene Metabolism Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
- alpha-Linolenic Acid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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