Thioredoxin - CISMeF

Preferred Label : Thioredoxin;

NCIt synonyms : Adult T Cell Leukemia-Derived Factor; TXN; ATL Derived Factor/Human Thioredoxin; ADF; Surface Associated Sulphydryl Protein; SASP; Human Thioredoxin; ATL-Derived Factor; ATL Derived Factor; Trx; Trx-1;

NCIt definition : Thioredoxin (105 aa, 12 kDa) is encoded by the human TXN gene. This protein plays a role in redox reactions, signaling and immunity.;

Details

Origin ID

C20465;

UMLS CUI

C1504637;

Currated CISMeF NLP mapping
- adult T cell leukemia-derived factor [MeSH concept]
- adult T cell leukemia-derived factor [MeSH Supplementary Concept]
OMIM relation
- Thioredoxin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TXN protein, human [MeSH concept]
- TXN protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
endogenous_product_related_to
- Thioredoxin [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- TXN Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Interferon Signaling Modulation Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- p38 MAPK Signaling Pathway PID [NCIt concept]
gene_product_malfunction_associated_with_disease
- Adult T-Cell Leukemia/Lymphoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- Thioredoxin-1 Inhibitor PX-12 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients