Pyruvate Carboxylase, Mitochondrial

Preferred Label : Pyruvate Carboxylase, Mitochondrial;

NCIt synonyms : Pyruvic Carboxylase; PCB; Pyruvate Carboxylase; PC; EC 6.4.1.1;

NCIt definition : Pyruvate carboxylase, mitochondrial (1178 aa, 130 kDa) is encoded by the human PC gene. This protein is involved in catalyzing the carboxylation of pyruvate to oxaloacetate.;

NCIt note : The active enzyme is a homotetramer of pyruvate carboxylase, mitochondrial.;

NCI Metathesaurus CUI : CL1799239;

Details

Origin ID

C190382;

UMLS CUI

C5780720;

Automatic exact mappings (from CISMeF team)
- Pachyonychia congenita [ORDO Disease]
- Podocalyxin-like [OMIM gene]
- Polychlorinated biphenyl [ICD-11 Extension code]
- Polychlorinated biphenyl (PCB) [LOINC component]
- Polychlorinated biphenyl (substance) [SNOMED CT concept]
- Protein C [OMIM gene]
- Pyruvate carboxylase [LOINC component]
- Pyruvate carboxylase [OMIM gene]
- Pyruvate carboxylase (substance) [SNOMED CT concept]
- paracentral nucleus [UBERON concept]
- podocalyxin like [ORDO Gene]
- pyruvate carboxylase [MeSH concept]
- pyruvate carboxylase [MeSH Descriptor]
- pyruvate carboxylase [SNOMED Notion]
- pyruvate carboxylase [ORDO Gene]
- pyruvate carboxylase [HGNC gene]
OMIM relation
- Pyruvate carboxylase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
- PC Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Citrate Cycle (TCA Cycle) Pathway [NCIt concept]
- Pyruvate Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Energy Metabolism Process [NCIt concept]
- Gluconeogenic Process [NCIt concept]
- Glycolysis [NCIt concept]
- Lipid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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