Palmitoyl-Protein Thioesterase 1

Preferred Label : Palmitoyl-Protein Thioesterase 1;

NCIt synonyms : EC 3.1.2.22; PPT-1; PPT1; Palmitoyl-Protein Hydrolase 1; Palmitoyl Protein Thioesterase 1; Ceroid-Palmitoyl-Palmitoyl-Protein Thioesterase 1;

NCIt definition : Palmitoyl-protein thioesterase 1 (306 aa, 34 kDa) is encoded by the human PPT1 gene. This protein is involved in the catalytic removal of fatty acyl chains from modified cysteine residues.;

Details

Origin ID

C178164;

UMLS CUI

C1447791;

Automatic exact mappings (from CISMeF team)
- Palmitoyl-protein thioesterase 1 [OMIM gene]
- palmitoyl-protein thioesterase [MeSH Supplementary Concept]
- palmitoyl-protein thioesterase 1 [ORDO Gene]
- palmitoyl-protein thioesterase 1 [HGNC gene]
- palmitoyl-protein thioesterase 1 [MeSH concept]
OMIM relation
- Palmitoyl-protein thioesterase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PPT1 protein, human [MeSH Supplementary Concept]
- PPT1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PPT1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Lysosome [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fatty Acid Elongation Pathway in Mitochondria [NCIt concept]
- Fatty Acid Metabolism Pathway [NCIt concept]
- Lysosome Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Receptor Mediated Endocytosis [NCIt concept]
is_target
- Ezurpimtrostat [NCIt concept]

Keyword's position in hierarchy(ies) :

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