Plasminogen - CISMeF

Preferred Label : Plasminogen;

NCIt synonyms : PLMN; EC 3.4.21.7; PLG; Fibrinolysin Precursor; Plasmin Precursor; Thrombolysin Precursor; Fibrinase Precursor;

NCIt definition : Plasminogen (810 aa, 91 kDa) is encoded by the human PLG gene. This protein is involved in fibrinolysis, platelet activation and tissue remodeling.;

NCIt note : Plasminogen conversion to the enzymatically active plasmin is mediated by plasminogen activator proteins and is dependent on binding to clots or cell surfaces.;

Details

Origin ID

C16994;

UMLS CUI

C5441720;

Currated CISMeF NLP mapping
- Plasminogen [SMS substance]
- Plasminogen [LOINC component]
- Plasminogen [MedDRA Preferred Term]
- Plasminogen (substance) [SNOMED CT concept]
- plasminogen [Substance BNPC]
- plasminogen [MeSH Descriptor]
- plasminogen [MeSH concept]
- plasminogen [SNOMED Notion]
- plasminogen (S741C-fluorescein) [MeSH concept]
- plasminogen (S741C-fluorescein) [MeSH Supplementary Concept]
OMIM relation
- Plasminogen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Plasminogen [LOINC component]
- Plasminogen (substance) [SNOMED CT concept]
- plasminogen [MeSH concept]
- plasminogen [SNOMED Notion]
- plasminogen [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PLG Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_biochemical_function
- Peptidase [NCIt concept]
gene_product_has_chemical_classification
- Beta Globulin [NCIt concept]
- Glycoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Kringle Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myocardial Infarction Pathway [NCIt concept]
- AlphaM/Beta2 Integrin Signaling Pathway [NCIt concept]
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- Complement and Coagulation Cascade [NCIt concept]
- Fibrinolysis Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- Platelet Amyloid Precursor Protein Pathway [NCIt concept]
- Syndecan-4-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]
- Proteolytic Processing [NCIt concept]
has_gene_product_element
- Angiostatin [NCIt concept]

Keyword's position in hierarchy(ies) :

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