Lysosomal Alpha-Glucosidase

Preferred Label : Lysosomal Alpha-Glucosidase;

NCIt synonyms : Acid Alpha-Glucosidase; Acid Maltase; EC 3.2.1.20; Aglucosidase Alfa; GAA;

NCIt definition : Lysosomal alpha-glucosidase (952 aa, 105 kDa) is encoded by the human GAA gene. This protein is involved in the hydrolysis of alpha-1,4- and alpha-1,6-linked glucans.;

NCIt note : Lysosomal alpha-glucosidase can be cleaved after residue 122 or residue 203 to generate a 76 kDa or 70 kDa form, respectively.;

Details

Origin ID

C216153;

OMIM relation
- Glucosidase, alpha, acid [OMIM gene]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GAA Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Exosome [NCIt concept]
- Lysosome [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Galactose Metabolism Pathway [NCIt concept]
- Lysosome Assembly Pathway [NCIt concept]
- Starch and Sucrose Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Catabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]

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