High Affinity cGMP-Specific 3',5'-Cyclic Phosphodiesterase 9A

Preferred Label : High Affinity cGMP-Specific 3',5'-Cyclic Phosphodiesterase 9A;

NCIt synonyms : Homo sapiens Phosphodiesterase PDE9A2; cGMP-Specific 3',5'-Cyclic Phosphodiesterase Type 9; EC 3.1.4.35; Phosphodiesterase PDE9A21; High Affinity cGMP-Specific 3,5-Cyclic Phosphodiesterase 9A; cGMP-Specific 3,5-Cyclic Phosphodiesterase Type 9; PDE9A;

NCIt definition : High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (593 aa, 68 kDa) is encoded by the human PDE9A gene. This protein plays a role in the conversion of cyclic nucleotide monophosphates to non-cyclic monophosphates.;

NCIt note : High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A may be involved in hypertrophic heart disease. (Nature. 2015; 519:472-476.);

NCI Metathesaurus CUI : CL504232;

Details

Origin ID

C125491;

UMLS CUI

C0760980;

OMIM relation
- Phosphodiesterase 9a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PDE9A protein, human [MeSH Supplementary Concept]
- PDE9A protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PDE9A Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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