PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase 1

Preferred Label : PH Domain Leucine-Rich Repeat-Containing Protein Phosphatase 1;

NCIt synonyms : hSCOP; PH Domain-Containing Family E Member 1; SCN Circadian Oscillatory Protein; EC 3.1.3.16; Pleckstrin Homology Domain-Containing Family E Member 1; Suprachiasmatic Nucleus Circadian Oscillatory Protein; PHLPP1;

NCIt definition : PH domain leucine-rich repeat-containing protein phosphatase 1 (1717 aa, 185 kDa) is encoded by the human PHLPP1 gene. This protein plays a role in both protein dephosphorylation and growth factor-mediated signaling.;

Details

Origin ID

C101358;

UMLS CUI

C0910244;

OMIM relation
- Ph domain and leucine-rich repeat protein phosphatase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PHLPP1 protein, human [MeSH concept]
- PHLPP1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PHLPP1 Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Serine/Threonine Phosphatase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine-Rich Repeat [NCIt concept]
- PH Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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