Stromelysin-1 - CISMeF

Preferred Label : Stromelysin-1;

NCIt synonyms : Transin-1; Stromelysin 1; MMP3; Proteoglycanase; ST1; Matrix Metalloproteinase-3; Matrix Metalloprotease 3; EC 3.4.24.17; Matrix Metalloprotease-3; SL-1; MMP-3; Matrix Metalloproteinase 3;

NCIt definition : Stromelysin-1 (477 aa, 54 kDa) is encoded by the human MMP3 gene. This protein is involved in cleavage of fibronectin, laminin and proteoglycans.;

Details

Origin ID

C17571;

UMLS CUI

C1723257;

Automatic exact mappings (from CISMeF team)
- 1,2-dihydroxy-4-(nitroethenyl)benzene [MeSH Supplementary Concept]
- Matrix metalloproteinase 3 [OMIM gene]
- SL-1 [MeSH concept]
- ST1 (body structure) [SNOMED CT concept]
- Stromelysin-1 [LOINC component]
- TATA-box binding protein associated factor, RNA polymerase I subunit A [ORDO Gene]
- matrix metalloproteinase 3 [MeSH Descriptor]
- matrix metalloproteinase 3 [MeSH concept]
- obsolete stromelysin 1 activity [GO term]
- proteoglycan-degrading metalloendopeptidases [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Matrix metalloproteinase-3 [MedDRA Preferred Term]
- Stromelysin 1 (substance) [SNOMED CT concept]
- progelatinase [MeSH concept]
- progelatinase [MeSH Supplementary Concept]
OMIM relation
- Matrix metalloproteinase 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MMP3 protein, human [MeSH concept]
- MMP3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MMP3 Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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