Histone Acetyltransferase KAT2B

Preferred Label : Histone Acetyltransferase KAT2B;

NCIt synonyms : p300 CBP-Associated Factor; PCAF; P/CAF; CREBBP-Associated Factor; Histone Acetylase PCAF; EC 2.3.1.48; Lysine Acetyltransferase 2B; p300/CBP-Associated Factor; Histone Acetyltransferase PCAF;

NCIt definition : Histone acetyltransferase KAT2B (832 aa, 93 kDa) is encoded by the human KAT2B gene. This protein is involved in both histone acetylation and transcriptional activation.;

Details

Origin ID

C17990;

UMLS CUI

C3887789;

Currated CISMeF NLP mapping
- p300-CBP-associated factor [MeSH concept]
- p300-CBP-associated factor [MeSH Supplementary Concept]
False automatic mappings
- acyl protein synthetase [MeSH Supplementary Concept]
- carbon monoxide-methylene blue oxidoreductase [MeSH Supplementary Concept]
- dextran alpha-(1-2)-debranching enzyme [MeSH Supplementary Concept]
- glycoside hydrolases [MeSH Descriptor]
- hydroxycinnamoyl-CoA anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase [MeSH Supplementary Concept]
- sialidase L [MeSH Supplementary Concept]
OMIM relation
- Lysine acetyltransferase 2b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- KAT2B Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Ligand Binding Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Chromatin Remodeling Complex and Coactivator Pathway [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
- FOXO Transcription Factor Family Signaling Pathway [NCIt concept]
- Gene Expression Regulation by Vitamin D Receptor Pathway [NCIt concept]
- HDAC Class I Signaling Pathway [NCIt concept]
- HDAC Class III Signaling Pathway [NCIt concept]
- IFN-Beta Enhancer Pathway [NCIt concept]
- Notch Signaling Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- Retinoic Acid Receptor Family-Mediated Signaling Pathway [NCIt concept]
- Skeletal Myogenesis Pathway [NCIt concept]
- p53 Pathway for Transcriptional Regulation [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Histone Acetylation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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