Glutathione S-Transferase Theta-2

Preferred Label : Glutathione S-Transferase Theta-2;

NCIt synonyms : Glutathione S-Transferase Theta 2; Glutathione-S-Transferase T2; GST Class-Theta-2; EC 2.5.1.18; GSTT2;

NCIt definition : Glutathione S-transferase theta-2 (244 aa, 28 kDa) is encoded by the human GSTT2 gene. This protein is involved in the conjugation of glutathione to hydrophobic electrophiles.;

NCI Metathesaurus CUI : CL937864;

Details

Origin ID

C158390;

UMLS CUI

C4761359;

Automatic exact mappings (from CISMeF team)
- Glutathione s-transferase, theta-2 [OMIM gene]
OMIM relation
- Glutathione s-transferase, theta-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GSTT2 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_biochemical_function
- Glutathione S-Transferase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Glutathione Metabolism Pathway [NCIt concept]
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]

Keyword's position in hierarchy(ies) :

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