Glutathione S-Transferase

Preferred Label : Glutathione S-Transferase;

NCIt synonyms : Glutathione S-Aralkyltransferase; EC 2.5.1.18; GST; Glutathione S-Aryltransferase; Glutathione S-Alkyltransferase; S-(Hydroxyalkyl)Glutathione Lyase;

NCIt definition : A class of enzymes that catalyze the reaction of glutathione with an acceptor molecule (an arene oxide) to form an S-substituted glutathione; a key step in detoxification of many substances; start of the mercapturic acid pathway.;

Alternative definition : NCI-GLOSS: A family of enzymes involved in metabolism and in making toxic compounds less harmful to the body.;

Codes from synonyms : CDR0000373012;

Details

Origin ID

C16641;

UMLS CUI

C0017837;

Biochemical function of gene products
- Glutathione S-Transferase A1 [NCIt concept]
- Glutathione S-Transferase A4 [NCIt concept]
- Glutathione S-Transferase Alpha [NCIt concept]
- Glutathione S-Transferase Mu [NCIt concept]
- Glutathione S-Transferase Mu 1 [NCIt concept]
- Glutathione S-Transferase Mu 3 [NCIt concept]
- Glutathione S-Transferase Mu 4 [NCIt concept]
- Glutathione S-Transferase P [NCIt concept]
- Glutathione S-Transferase Theta-1 [NCIt concept]
- Glutathione S-Transferase Theta-2 [NCIt concept]
- Maleylacetoacetate Isomerase [NCIt concept]
- Microsomal Glutathione S-Transferase 2 [NCIt concept]
Currated CISMeF NLP mapping
- Glutathione S-transferase [LOINC component]
- Glutathione transferase (substance) [SNOMED CT concept]
- glutathione transferase [SNOMED Notion]
- glutathione transferase [MeSH Descriptor]
- glutathione transferase [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Glutathione S-transferase [LOINC component]
- Glutathione transferase (substance) [SNOMED CT concept]
- glutathione transferase [MeSH concept]
- glutathione transferase [SNOMED Notion]
- glutathione transferase [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Transferase Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Etanidazole [NCIt concept]
gene_product_has_biochemical_function
- Alkyltransferase and Aryltransferase [NCIt concept]
is_target
- Etanidazole [NCIt concept]

Keyword's position in hierarchy(ies) :

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