UDP-Glucuronosyltransferase 1-4

Preferred Label : UDP-Glucuronosyltransferase 1-4;

NCIt synonyms : UGT1.4; UGT1D; UGT1*4; EC 2.4.1.17; UDP-Glucuronosyltransferase 1-D; Bilirubin UDP-Glucuronosyltransferase Isozyme 2; UDPGT 1-4; hUG-BR2; UDP-Glucuronosyltransferase 1A4; Bilirubin-Specific UDPGT Isozyme 2; UGT-1D; UGT1-04; UGT1A4;

NCIt definition : UDP-glucuronosyltransferase 1-4 (534 aa, 60 kDa) is encoded by the human UGT1A4 gene. This protein is involved in glucuronidation of toxins.;

Details

Origin ID

C113634;

UMLS CUI

C5442125;

Automatic exact mappings (from CISMeF team)
- UGT1.4 [MeSH concept]
- Udp-glycosyltransferase 1 family, polypeptide a4 [OMIM gene]
- bilirubin glucuronoside glucuronosyltransferase [MeSH Supplementary Concept]
OMIM relation
- Udp-glycosyltransferase 1 family, polypeptide a4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- UGT1.4 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- UGT1A4 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hepatic Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ascorbate and Aldarate Metabolism Pathway [NCIt concept]
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
- Pentose and Glucuronate Interconversions Pathway [NCIt concept]
- Porphyrin and Chlorophyll Metabolism Pathway [NCIt concept]
- Retinol Metabolism Pathway [NCIt concept]
- Starch and Sucrose Metabolism Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients