E3 Ubiquitin-Protein Ligase TRAF7

Preferred Label : E3 Ubiquitin-Protein Ligase TRAF7;

NCIt synonyms : EC 6.3.2.-, Formerly; RING Finger and WD Repeat-Containing Protein 1; RING Finger Protein 119; Ring Finger and WD Repeat Domain 1; RING Finger and WD Repeat Domains-Containing Protein 1; TNF Receptor-Associated Factor 7; RING-Type E3 Ubiquitin Transferase TRAF7; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase TRAF7 (670 aa, 75 kDa) is encoded by the human TRAF7 gene. This protein is involved in both protein ubiquitination and MAPK signaling.;

NCIt note : E3 ubiquitin-protein ligase TRAF7 is capable of auto-ubiquitination. (UniProt);

Details

Origin ID

C107648;

UMLS CUI

C1452015;

Automatic exact mappings (from CISMeF team)
- Tnf receptor-associated factor 7 [OMIM gene]
OMIM relation
- Tnf receptor-associated factor 7 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TRAF7 protein, human [MeSH Supplementary Concept]
- TRAF7 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- TRAF7 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membranous Cytoplasmic Organelle [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- WD Repeat [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Positive Regulation of Apoptosis [NCIt concept]
- Signal Transduction Induction [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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