Tyrosine 3-Monooxygenase

Preferred Label : Tyrosine 3-Monooxygenase;

NCIt synonyms : Tyrosine 3-Hydroxylase; TH; EC 1.14.16.2;

NCIt definition : Tyrosine 3-monooxygenase (528 aa, 59 kDa) is encoded by the human TH gene. This protein plays a role in the synthesis of dopamine from L-tyrosine.;

Details

Origin ID

C127896;

UMLS CUI

C4285344;

Automatic exact mappings (from CISMeF team)
- Tyrosine 3-monooxygenase (substance) [SNOMED CT concept]
- Tyrosine hydroxylase [OMIM gene]
- dorsal plus ventral thalamus [UBERON concept]
- liver transplantation [MeSH Descriptor]
- therapeutics [MeSH Descriptor]
- tyrosine 3-Monooxygenase [MeSH concept]
- tyrosine 3-Monooxygenase [MeSH Descriptor]
- tyrosine 3-monooxygenase [SNOMED Notion]
- tyrosine hydroxylase [ORDO Gene]
- tyrosine hydroxylase [HGNC gene]
OMIM relation
- Tyrosine hydroxylase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- TH Gene [NCIt concept]
gene_product_expressed_in_tissue
- Adrenal Gland [NCIt concept]
- Brain [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Parkinson's Disease Pathway KEGG [NCIt concept]
- Tyrosine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biogenic Amine Metabolic Process [NCIt concept]
- Biosynthetic Process [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- Racemetyrosine [NCIt concept]
- Racemetyrosine/Methoxsalen/Phenytoin/Sirolimus [NCIt concept]

Keyword's position in hierarchy(ies) :

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