Alanine-tRNA Ligase, Mitochondrial

Preferred Label : Alanine-tRNA Ligase, Mitochondrial;

NCIt synonyms : Alanyl-tRNA Synthetase 2, Mitochondrial; AARS2; Alanyl-tRNA Synthetase; AlaRS; Alanyl-tRNA Ligase, Mitochondrial; Alanyl-tRNA Synthetase, Mitochondrial; Alanyl tRNA Ligase 2, Mitochondrial; EC 6.1.1.7; Alanyl-tRNA Synthetase 2; Alanyl--tRNA Ligase, Mitochondrial;

NCIt definition : Alanine-tRNA ligase, mitochondrial (985 aa, 107 kDa) is encoded by the human AARS2 gene. This protein plays a role in mitochondrial aminoacylation of alanyl-tRNA.;

NCI Metathesaurus CUI : CL1374906;

Details

Origin ID

C190307;

UMLS CUI

C5197148;

Automatic exact mappings (from CISMeF team)
- Alanine-tRNA ligase [MeSH Descriptor]
- Alanine-transfer ribonucleic acid ligase (substance) [SNOMED CT concept]
- Alanyl-trna synthetase 1 [OMIM gene]
- Alanyl-trna synthetase 2 [OMIM gene]
- Alare [FMA entity]
- alanine-tRNA ligase activity [GO term]
- alanyl-tRNA synthetase 1 [ORDO Gene]
- alanyl-tRNA synthetase 2, mitochondrial [ORDO Gene]
- alanyl-tRNA synthetase 2, mitochondrial [HGNC gene]
- daminozide [MeSH Supplementary Concept]
OMIM relation
- Alanyl-trna synthetase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- AARS2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- AARS2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrion [NCIt concept]
gene_product_has_biochemical_function
- Aminoacyl-tRNA Ligase Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aminoacyl-tRNA Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- RNA Processing [NCIt concept]
- Translational Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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