Serine Protease HTRA1

Preferred Label : Serine Protease HTRA1;

NCIt synonyms : High-Temperature Requirement A Serine Peptidase 1; Serine Protease 11; EC 3.4.21.-; IGFBP5-Protease; L56; HTRA1;

NCIt definition : Serine protease HTRA1 (480 aa, 51 kDa) is encoded by the human HTRA1 gene. This protein plays a role in the proteolysis of IGF-binding proteins.;

Details

Origin ID

C101311;

UMLS CUI

C1258300;

OMIM relation
- Htra serine peptidase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- HtrA1 protein, human [MeSH concept]
- HtrA1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- HTRA1 Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_chemical_classification
- Extracellular Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- PDZ Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Growth Regulation [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients