Geranylgeranyl Transferase Type-1 Subunit Beta

Preferred Label : Geranylgeranyl Transferase Type-1 Subunit Beta;

NCIt synonyms : GGTI; BGGI; GGTase-I-Beta; Geranylgeranyl Transferase Type I Beta Subunit; PGGT1B; Type I Protein Geranyl-Geranyltransferase Beta Subunit; Protein Geranylgeranyltransferase Type-I Beta Subunit; Geranylgeranyl Transferase Type I Subunit Beta; Protein Geranylgeranyltransferase Type I Beta Subunit; EC 2.5.1.59;

NCIt definition : Geranylgeranyl transferase type-1 subunit beta (377 aa, 42 kDa) is encoded by the human PGGT1B gene. This protein plays a role in protein geranylgeranylation.;

NCIt note : Geranylgeranyl transferase activity is dependent on formation of a complex of geranylgeranyl transferase type-1 subunit beta with protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha. Geranylgeranyl transferase type-1 subunit beta is responsible for substrate recognition. (UniProt);

Details

Origin ID

C41055;

UMLS CUI

C1514546;

OMIM relation
- Protein geranylgeranyltransferase type I, beta subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PGGT1B protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PGGT1B Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_physical_part_of
- Geranylgeranyl Transferase [NCIt concept]
gene_product_plays_role_in_biological_process
- Isoprenylation Process [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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