Lysine-Specific Demethylase 5A

Preferred Label : Lysine-Specific Demethylase 5A;

NCIt synonyms : KDM5A; RBBP-2; EC 1.14.11.-; Retinoblastoma-Binding Protein 2; Jumonji/ARID Domain-Containing Protein 1A; Histone Demethylase JARID1A;

NCIt definition : Lysine-specific demethylase 5A (1690 aa, 192 kDa) is encoded by the human KDM5A gene. This protein plays a role in both histone demethylation and the positive regulation of gene transcription.;

Details

Origin ID

C97597;

UMLS CUI

C0140274;

OMIM relation
- Lysine demethylase 5a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- KDM5A protein, human [MeSH concept]
- KDM5A protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- KDM5A Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
gene_product_has_structural_domain_or_motif
- ARID Domain [NCIt concept]
- PHD Finger [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Histone Demethylation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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