Estradiol 17-Beta-Dehydrogenase 2

Preferred Label : Estradiol 17-Beta-Dehydrogenase 2;

NCIt synonyms : EC 1.1.1.62; 17-Beta-HSD; 17-Beta Hydroxysteroid Dehydrogenase; HSD17B2; Estradiol 17 Beta-Dehydrogenase; Testosterone 17-Beta-Dehydrogenase; 17-Beta-Hydroxysteroid Dehydrogenase Type 2; 17-Beta-HSD 2; 20-Alpha-HSD; Microsomal 17-Beta-Hydroxysteroid Dehydrogenase; Hydroxysteroid 17-Beta Dehydrogenase 2; E2DH; EC 1.1.1.63; 20 Alpha-Hydroxysteroid Dehydrogenase; Hydroxysteroid-17-Beta Dehydrogenase-2;

NCIt definition : Estradiol 17-beta-dehydrogenase 2 (387 aa, 43 kDa) is encoded by the human HSD17B2 gene. This protein is involved in the synthesis of both androgens and estrogens.;

Details

Origin ID

C16254;

UMLS CUI

C2002897;

Automatic exact mappings (from CISMeF team)
- 17-Hydroxysteroid dehydrogenases [MeSH Descriptor]
- 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity [GO term]
- 17-beta-hydroxysteroid dehydrogenase II [OMIM gene]
- 20-alpha-Hydroxysteroid dehydrogenase [MeSH concept]
- 20-alpha-hydroxysteroid dehydrogenase [MeSH Descriptor]
- 20-alpha-hydroxysteroid dehydrogenase (substance) [SNOMED CT concept]
- 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)) [MeSH Supplementary Concept]
- 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)) [MeSH concept]
- 3beta-hydroxysteroid dehydrogenase (substance) [SNOMED CT concept]
- AKR1C13 protein, mouse [MeSH Supplementary Concept]
- AKR1C16 protein, mouse [MeSH Supplementary Concept]
- Akr1c6 protein, mouse [MeSH Supplementary Concept]
- HSD17B1 protein, human [MeSH Supplementary Concept]
- HSD17B2 protein, human [MeSH Supplementary Concept]
- Testosterone 17beta-dehydrogenase (substance) [SNOMED CT concept]
- estradiol 17-beta-dehydrogenase activity [GO term]
- estradiol dehydrogenases [MeSH Descriptor]
- hydroxysteroid 17-beta dehydrogenase 2 [HGNC gene]
- testosterone 17-beta-dehydrogenase (NAD+) activity [GO term]
- testosterone 17beta-dehydrogenase [SNOMED Notion]
- testosterone dehydrogenase (NAD+) activity [GO term]
Currated CISMeF NLP mapping
- 17 beta-Hydroxysteroid dehydrogenases [MeSH concept]
- estradiol 17 beta-Dehydrogenase [MeSH concept]
OMIM relation
- 17-beta-hydroxysteroid dehydrogenase II [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Estradiol 17beta-dehydrogenase (substance) [SNOMED CT concept]
- HSD17B2 protein, human [MeSH concept]
- HSD17B2 protein, human [MeSH Supplementary Concept]
- estradiol 17 beta-Dehydrogenase [MeSH concept]
- estradiol 17beta-dehydrogenase [SNOMED Notion]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- HSD17B2 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Endoplasmic Reticulum [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Disease Marker [NCIt concept]
gene_product_is_element_in_pathway
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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