Spastin - CISMeF

Preferred Label : Spastin;

NCIt synonyms : Spastic Paraplegia 4 Protein; EC 5.6.1.1; SPAST;

NCIt definition : Spastin (616 aa, 67 kDa) is encoded by the human SPAST gene. This protein is involved in the ATP-dependent depolymerization of polyglutamylated microtubules.;

Details

Origin ID

C208015;

OMIM relation
- Spastin [OMIM gene]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Isomerase Gene [NCIt concept]
- SPAST Gene [NCIt concept]
gene_product_has_associated_anatomy
- Centrosome [NCIt concept]
- Cytosol [NCIt concept]
- Exosome [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
- Nucleoplasm [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- Phosphoglycerate Mutase Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- ATPase Domain [NCIt concept]
- Nuclear Localization Signal [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Microtubule Process [NCIt concept]
- Protein Metabolism Process [NCIt concept]
- Tubulin Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients