Accès restreintPropriété BDBfr

2023
http://www.ncbi.nlm.nih.gov/pubmed/37977719
https://linkinghub.elsevier.com/retrieve/pii/S1701-2163(23)00383-3
Turner S
Allen VM
Carson G
Graves L
Tanguay R
Green CR
Cook JL
10.1016/j.jogc.2023.05.014
AbstractText Label OBJECTIF Présenter aux professionnels de la santé les données probantes concernant l'utilisation des opioïdes et la santé des femmes. Les domaines d'intérêt sont la grossesse et les soins post-partum. /AbstractText AbstractText Label POPULATION CIBLE Toutes les femmes qui utilisent des opioïdes. RéSULTATS: Un dialogue ouvert et éclairé sur l'utilisation des opioïdes améliorera les soins aux patientes. BéNéFICES, RISQUES ET COûTS: L'exploration de l'utilisation d'opioïdes par une approche tenant compte des traumatismes antérieurs donne au professionnel de la santé et à la patiente l'occasion de bâtir une alliance solide, collaborative et thérapeutique. Cette alliance permet aux femmes de faire des choix éclairés. Elle favorise le diagnostic et le traitement possible du trouble lié à l'utilisation d'opioïdes. L'utilisation ne doit pas être stigmatisée, puisque la stigmatisation affaiblit le partenariat (le partenariat entre patiente et professionnel de la santé). Les professionnels de la santé ceus-ci doivent comprendre l'effet potentiel des opioïdes sur la santé les femmes enceintes et les aider à prendre des décisions éclairées sur leur santé. DONNéES PROBANTES: Une recherche a été conçue puis effectuée dans les bases de données PubMed et Cochrane Library pour la période d'août 2018 à mars 2023 des termes MeSH et mots clés suivants (et variantes) : opioids, opioid agonist therapy, illicit drugs, fertility, pregnancy, fetal development, neonatal abstinence syndrome et breastfeeding. MéTHODES DE VALIDATION: Les auteurs ont évalué la qualité des données probantes et la force des recommandations en utilisant le cadre méthodologique GRADE (Grading of Recommendations, Assessment, Development, and Evaluation). Voir l'annexe A en ligne (tableau A1 pour les définitions et tableau A2 pour l'interprétation des recommandations fortes et conditionnelles [faibles]). PROFESSIONNELS CONCERNéS: Tous les professionnels de la santé qui prodiguent des soins aux femmes et aux nouveaux-nés. RéSUMé POUR TWITTER: La consommation d'opioïdes pendant la grossesse coïncide souvent avec des problèmes de santé mentale et est associée à des conséquences néfastes pour la mère, le fœtus et le nouveau-né ; le traitement des troubles liés à la consommation d'opioïdes par agonistes peut être sûr pendant la grossesse lorsque les risques sont plus nombreux que les avantages. DÉCLARATIONS SOMMAIRES: RECOMMANDATIONS. /AbstractText
11
102146
45
dépendance; grossesse; opioïdes; post-partum; santé des femmes; traitement de maintien
Novembre
S1701-2163(23)00383-3
publication papier
Accès restreint
guide de bonnes pratiques

---
2023
http://www.ncbi.nlm.nih.gov/pubmed/37977725
https://linkinghub.elsevier.com/retrieve/pii/S1701-2163(23)00382-1
Turner S
Allen VM
Graves L
Tanguay R
Green CR
Cook JL
10.1016/j.jogc.2023.05.013
11
102145
45
contraception; douleur pelvienne; fertilité; ménopause; opioïdes; santé des femmes
Novembre
S1701-2163(23)00382-1
publication papier
Accès restreint
guide de bonnes pratiques

---
État des lieux de la mise en place en France des entretiens pharmaceutiques en officine : analyse des réponses issues d’un questionnaire.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38158271
https://linkinghub.elsevier.com/retrieve/pii/S0040-5957(23)00195-6
Barat E
Pouant C
Soubieux A
Arrii M
Bardet JD
Chenailler C
Varin R
10.1016/j.therap.2023.11.010
AbstractText Label OBJECTIVE To evaluate the development of pharmaceutical interviews in pharmacies in France, in order to understand the organization implemented, any limitations and the expansion of eligible pathologies. /AbstractText AbstractText Label METHOD A dematerialized questionnaire was designed and distributed between November 2022 and February 2023 to pharmacists and pharmacy students in France (mainland and overseas) via a link to a Google Form. /AbstractText AbstractText Label RESULTS Ninety-four pharmacists from 8 different regions of France responded to the survey. The 94 responses showed that 56% of pharmacists practiced pharmaceutical interviews. Among pharmacists who practiced interviews, pharmacy owners practiced significantly more interviews than other statuses within the pharmacy (67% vs. 38% P 0.014). No other factor, such as dispensary size or geographical area of practice, had a significant impact on whether or not pharmaceutical interviews were carried out. These talks are often carried out at the patient's request, and 89% of them are accompanied by documents for the patient's attention. For pharmacists who do not carry out interviews, time, staffing and remuneration are the 3 main blocking factors found in both quantitative and verbatim variables. Whether or not pharmacists carry out pharmaceutical interviews, this activity received 87% approval from the 94 respondents, and 84% of them would like to include more chronic disease themes. /AbstractText AbstractText Label CONCLUSION The survey shows that pharmacists approve of the pharmaceutical interviewing activity, but it also highlights obvious logistical obstacles linked to a lack of resources. Thus, even among pharmacists who carry out pharmaceutical interviews, this activity is still carried out relatively infrequently on a routine basis, and often by the incumbent pharmacist, who takes on the responsibility of carrying out this activity. /AbstractText
entretiens pharmaceutiques; iatrogeny; iatrogénie; officine; parcours patient; patient pathway; pharmaceutical care; pharmaceutical interviews; pharmacy; soins pharmaceutiques
16
Décembre
S0040-5957(23)00195-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique

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Une hémoptysie.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38158293
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01323-1
El Amrani S
Imrani K
Charlemagne KEM Jr
Moatassim Billah N
Nassar I
10.1016/j.revmed.2023.12.006
angioscanner; ct angiography; hemoptysis; hémoptysie; pulmonary sequestration; séquestration pulmonaire
28
Décembre
S0248-8663(23)01323-1
publication avant impression
Accès restreint
article de périodique

---
Gestion des toxicités des immunothérapies du cancer : challenges et « rechallenges » pour les (jeunes) internistes.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38158294
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01320-6
Guitton R
Lambotte O
Chiche L
10.1016/j.revmed.2023.12.003
1
1-5
45
autoimmune diseases; cancer immunotherapy; effets indésirables immuno-médiés; immune checkpoint inhibitor; immune-related adverse events; immunothérapie anticancéreuse; inhibiteur du point de contrôle; internal medicine; maladies auto-immunes; médecine interne
28
Janvier
S0248-8663(23)01320-6
publication avant impression
Accès restreint
article de périodique
humains
immunothérapie
tumeurs

---
Diagnostic et évaluation de l’hépatopathie stéatosique métabolique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38158295
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)00880-9
Canivet CM
Faure S
10.1016/j.revmed.2023.10.438
Non-alcoholic fatty liver disease (NAFLD) or recently called Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD), is the leading cause of liver disease, with an estimated worldwide prevalence of 25%. MASLD is suspected, in a metabolic condition, in the presence of hepatic steatosis, moderate hepatic cytolysis or hyperferritinemia. The severity of the disease depends on the stage of liver fibrosis, which can be suspected in clinical practice by simple blood tests such as the FIB-4 or NAFLD fibrosis Score. The treatment is based on lifestyle intervention combining weight loss, increased physical activity and a Mediterranean-style diet. Only a small minority of patients with MASLD will develop advanced liver disease and require liver specialist. Given the high prevalence of MASLD, the identification of these patients cannot be envisaged without the taking part in the screening of all physicians (general practitioners and specialists).
1
41-47
45
cirrhose; cirrhosis; fibrose hhépatique; liver fibrosis; masld; metabolic syndrome; nafld; non-invasive liver fibrosis test; syndrome métabolique; test non invasif de fibrose hépatique
28
Janvier
S0248-8663(23)00880-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
Stéatose hépatique non alcoolique
Stéatose hépatique non alcoolique
Stéatose hépatique non alcoolique
maladies métaboliques
médecins généralistes
mode de vie

---
Étude comparative des processus de production et de contrôle analytique des préparations magistrales de mélanges nutritifs parentéraux en néonatalogie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38159720
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(23)00167-0
Bosson A
Durand M
Mazet R
Romaszko MJ
Chennell P
Mounsef F
Quessada T
Choisnard L
Bedouch P
10.1016/j.pharma.2023.12.009
AbstractText Label OBJECTIVES To assess the impact of disparities in production and analytical control processes on the quality of parenteral nutrition (PN) preparations produced in the Auvergne-Rhône-Alpes region. /AbstractText AbstractText Label METHODS This study was carried out in four hospital pharmacies of the Auvergne-Rhône-Alpes region. To assess the impact of production processes, each centre produced ten PN preparations from the same prescription. Analytical controls (sodium, potassium and calcium dosage) were carried out on all the preparations. To assess the impact of the control processes, a batch of ten preparations was produced from the same prescription. Samples were sent to the four hospital pharmacies for analytical control (sodium, potassium and calcium dosage). /AbstractText AbstractText Label RESULTS Measurements of relative production bias show that there is a significant difference between the preparations from the four centres in terms of sodium and potassium content. Each centre had at least one production bias for one of the three electrolytes measured. Concerning analytical controls, there was a significant difference between the four centres in the sodium and potassium levels measured. With the exception of calcium, all the centres reported measurements within the usual specifications of /-10% of the target value. The results obtained have no clinically significant impact. /AbstractText AbstractText Label CONCLUSION The diversity of NP practices has a real impact on the quality of the preparations made. A regional collaboration should be envisaged to standardise patient care. /AbstractText
2
306-317
82
compounding; hospital pharmacy; parenteral nutrition; quality control
28
Mars
S0003-4509(23)00167-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
calcium
sodium
potassium
humains
néonatologie
nutrition parentérale

---
Infarctus du myocarde sans artères coronaires obstructives : rôle central de l’imagerie.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38160097
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)00765-8
Sedoud B
Barone-Rochette G
10.1016/j.revmed.2023.10.455
Myocardial infarction with non-obstructive coronary lesion (MINOCA) represents a non-negligible percentage of the proportion of myocardial infarctions ( 6%). Moreover, the long-term prognosis is poor, with an annual mortality rate of 2%. This high mortality rate may be explained by the fact that MINOCA represents a heterogeneous group, and the diagnosis of pathology is poorly understood. It is essential to be aware of this clinical presentation, and to follow the different diagnostic strategies, in order to identify the etiological mechanism, and thus set up a suitable treatment. Many tools are available to support diagnosis, notably in the fields of imaging, the principal contributors being coronary angiography, coronary physiology and pharmacological testing, as well as endo-coronary imaging and cardiac MRI. This review will provide an update on the definition, epidemiology, diagnostic strategies and treatment options for patients with MINOCA.
cardiovascular imaging; endo-coronary imaging and cardiac mri; imagerie cardiovasculaire; imagerie endocoronaire et irm cardiaque; minoca
29
Décembre
S0248-8663(23)00765-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

---
L’haploinsuffisance de A20 : que doit connaître le clinicien?
2023
http://www.ncbi.nlm.nih.gov/pubmed/38160098
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01321-8
Elhani I
Aouba A
Riller Q
Vergneault H
Boursier G
Rieux-Laucat F
Hentgen V
Georgin-Lavialle S
10.1016/j.revmed.2023.12.004
A20 Haploinsufficiency (HA20) is a monogenic autoinflammatory disease associated with an autosomal dominant mutation in the TNFAIP3 gene. It induces a defect in the inactivation of the pro-inflammatory NF-κB pathway. Less than 200 cases have been described worldwide. The clinical picture of the disease is essentially based on the association of recurrent fever and/or biologic inflammatory syndrome, aphtosis, often bipolar, and cutaneous folliculitis. However, the clinical spectrum of HA20 is very broad, including gastrointestinal (mainly colonic ulceration), articular, cutaneous, pericardial and lymph node involvement, as well as frequent association with organ-specific or non-specific autoimmune manifestations and/or autoantibodies, including antinuclear antibodies and anti-dsDNA. As a result, the diagnosis of a number of systemic or organic disorders, most notably Behçet's disease, Crohn's disease, and sometimes even systemic lupus, has been corrected to HA20 by molecular research for a heterozygous mutation with functional deficiency of TNFAIP3. Although the first signs of the disease often appear in the first years of life, the diagnosis is often made in adulthood and requires the involvement of both paediatric and adult physicians. Treatment for HA20 is not codified and relies on conventional or biological immunomodulators and immunosuppressants adapted to the patient's symptomatology. This review highlights the enormous diagnostic challenges in this autoinflammatory disease.
a20 haploinsufficiency; autoimmunity; autoimmunité; autoinflammatory disease; haploinsuffisance de a20; maladie autoinflammatoire; maladie de behcet; tnfaip3; maladie de crohn
29
Décembre
S0248-8663(23)01321-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

---
Utilisation des anti-infectieux au sein d’un centre hospitalier universitaire mère–enfant au Canada : une étude observationnelle.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38160789
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(23)00170-0
Monnier A
Roy H
Blackburn J
Bussières JF
10.1016/j.pharma.2023.12.012
AbstractText Label INTRODUCTION The proper use of antimicrobials is a challenge in healthcare establishments. /AbstractText AbstractText Label OBJECTIVES Describe the detailed antimicrobial consumption profile in 2021-2022. Describe the annual evolutionary profile of the use of antimicrobials in days of therapy/1000 patient days, antibiotic spectrum index/1000 patients days and according to the proportion of days of therapy administered by parenteral route from 2005-2006 to 2021-2022. /AbstractText AbstractText Label METHOD Descriptive and retrospective study. All patients admitted to our mother-child hospital center between April 1, 2005 and March 31, 2022 were included. The study covers the consumption of all antimicrobials through the AWaRe classification of the World Health Organization and antibiotic spectrum index. /AbstractText AbstractText Label RESULTS A total of 673.9 days of therapy/1000patients days was calculated in 2021-2022, i.e. 550.8 for antibiotics, 46.5 for antivirals, 67.9 for antifungals and 8.7 for others. A total of 2436 ASI/1000 patient days was calculated in 2021-2021. According to the AWaRe classification, in 2021-2022, 52.1% (287/551) of days of therapy/1000patients days referred to the Access group, 47.8% (263/551) to the Watch group and 0.2% (1/551) to the Reserve group. /AbstractText AbstractText Label CONCLUSION This study aims to explore the use of antimicrobials in a mother-child hospital center. It puts into perspective a stable or even slightly decreasing use of a selection of antimicrobials and compares favorably with published data. Antibiotic governance is based in particular on the periodic evaluation of consumption. Our study illustrates different approaches to quantify and describe this use. /AbstractText
2
318-328
82
asi; antibiotic stewardship; antimicrobials; treatment days; utilization
29
Mars
S0003-4509(23)00170-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
étude d'observation
anti-infectieux
antibactériens
humains
études rétrospectives
anti-infectieux
antibactériens
hôpitaux universitaires
Canada
relations mère-enfant

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Surveillance des effets indésirables lors des campagnes de la chimioprévention du paludisme saisonnier chez les enfants de 3-59 mois au Burkina Faso.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172043
Ouoba J
Lankoandé-Haro S
Fofana S
Nacoulma AP
Kaboré L
Sombié I
Rouamba T
Kirakoya-Samadoulougou F
10.3917/spub.235.0121
AbstractText Label INTRODUCTION Seasonal malaria chemoprevention (SMC) by mass administration of sulfadoxine pyrimethamine amodiaquine (SPAQ) reduces the burden of malaria in children aged 3–59 months. The occurrence of adverse drug reaction (ADR) may affect the success of this intervention. There are few studies of SMC adverse event surveillance in sub-Saharan Africa, particularly in Burkina Faso, a highly endemic country. Our main objective was to characterize the ADRs reported during SMC campaigns in Burkina Faso. Secondly, we evaluated the performance of the pharmacovigilance integrated into the SMC program in order to support safe administration of SMC. /AbstractText AbstractText Label METHOD This was a retrospective descriptive study of SMC individual case safety reports recorded in VigiBase in Burkina Faso from 2014 to 2021. We used the P-method for the analysis of preventable serious adverse drug reactions and WHO criteria for assessing the performance of pharmacovigilance integrated into the SMC program. /AbstractText AbstractText Label RESULTS A total of 1,105 SMC individual case safety reports were registered in VigiBase for 23,311,453 doses of SPAQ given between 2014 and 2021. No pharmacovigilance signal was detected. The number of serious cases was 101, of which 23 (22.8%) were preventable. In 38.1% of children, the occurrence of ADRs led to discontinuation of SMC treatment. Vomiting was the most frequently reported adverse drug reaction (48.0%). The proportion of children whose treatment was discontinued due to vomiting was 42.7%, while the proportion of treatment discontinuation for other ADRs was 32.8% (p 0.01). The SMC program contributed at 46.2% to the national pharmacovigilance database. The reporting rate was 0.03 per 1,000 exposed children in 2021. The median completeness score of the ICSRs was 0.7 (IQR: 0.5–0.7), and the median time to register the ICSRs in VigiBase was 204 (IQR: 143–333) days. /AbstractText AbstractText Label... AbstractText Label CONCLUSIONS Les vomissements peuvent nuire à l’objectif de la CPS. Des mesures de gestion de cet effet indésirable doivent être prises pour améliorer le succès de la CPS. Au regard des informations sur le délai de notification et le taux de notification, la notification spontanée devrait être soutenue par une surveillance active, notamment une « cohort event monitoring » au Burkina Faso. /AbstractText
5
121-132
35
seasonal malaria chemoprevention; adverse drug reactions; children under 5 years old; pharmacovigilance; burkina faso
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
antipaludiques
amodiaquine
enfant
humains
nourrisson
antipaludiques
Burkina
études rétrospectives
saisons
paludisme
paludisme
amodiaquine
chimioprévention
effets secondaires indésirables des médicaments
vomissement

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Accès aux soins d’une population d’anciens travailleurs immigrés vivant en foyer.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172044
Bettayeb L
Jaffré Y
Chiaroni J
Ennomany Y
Villani P
Couderc AL
10.3917/spub.235.0013
The Chibanis represent the population of aging former immigrant workers who arrived in France in the 1970s in order to take up employment. Most of them still live in immigrant hostels, which are not appropriate for an older population. This anthropological study was conducted on Chibanis living in an immigrant hostel in the 15th arrondissement of Marseille. The objectives were to assess the medical, economic, and social characteristics of this population, to understand their access to health care, and to measure their adherence to the prevention actions of an association. 67 Chibanis aged 65 and over were included, with a median age of 77: 91% had access to a general practitioner, and 86.6% had more than two chronic diseases. More than half of the Chibanis complained of dental problems, and 20% complained of ophthalmological problems. Only 32.8% of the Chibanis included agreed to follow-up care with the nurses from the association. The population of Chibanis are isolated geographically from their families, live in poor socio-economic conditions, and often have insufficient medico-social coverage. They must “manage” their chronic diseases, as well as costly health problems such as dental or ophthalmic diseases. Improving care pathways for this population requires us to identify their specificities and all the factors hindering prevention actions.Les Chibanis – “cheveux blancs” en arabe dialectal – désignent les anciens travailleurs immigrés arrivés en France dans les années 1970 pour exercer un emploi. Ils vivent encore pour la plupart au sein de foyers construits pour des hommes seuls exerçant une profession et non pour accueillir des hommes en situation de vieillissement. Notre travail anthropologique s’est organisé autour d’une population de Chibanis, vivant dans un foyer dans le 15e arrondissement de Marseille. Les objectifs étaient de mieux connaître cette population d’un point de vue médico-socio-culturel, de connaître les modalités de leur accès aux soins et enfin de connaître leur adhésion aux actions de prévention d’une association. 67 Chibanis 65 ans ont été inclus, avec une médiane de l’âge de 77 ans : 91 % déclaraient avoir un médecin traitant, 86,6 % avaient plus de 2 maladies chroniques. Plus de la moitié des Chibanis souffraient de problèmes dentaires et près de 20 % présentaient des problèmes ophtalmologiques. Seuls 32,8 % des Chibanis inclus ont accepté de réaliser un suivi par les infirmiers. La population des Chibanis, isolée géographiquement de leur famille, économiquement précaire et avec une couverture médico-sociale souvent insuffisante, doit « gérer » ses pathologies chroniques, et des problèmes de santé notamment dentaires et ophtalmiques couteux. L’amélioration de leurs parcours de santé nécessite de mieux comprendre leurs spécificités et les divers facteurs qui peuvent entraver les actions de prévention.
5
13-17
35
fraglity; migration; isolation; chronic diseases prevention
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
vieillissement
émigrants et immigrants
emploi
maladie chronique
accessibilité des services de santé
sujet âgé

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État des lieux de la situation du tabagisme en France : tendances observées et nouveaux enjeux.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172045
Obradovic I
Pasquereau A
Spilka S
Andler R
Douchet MA
Guignard R
Beck F
Nguyen-Thanh V
10.3917/spub.pr1.0021
This article reports changes in tobacco and vaping consumption in France over the last thirty years and the issues they raise for public authorities in terms of prevention and management of the social and health consequences. This report is the result of a joint analysis by Santé publique France (SpF) and the French Monitoring Center for Drugs and Drug Addiction (OFDT). It shows that there has been a “generational shift” in tobacco consumption and social representations of cigarettes since the mid-2010s, with a sharp decline in tobacco initiation among adolescents, which has become less common and reported at an older age, which was one of the objectives of the national tobacco reduction plans. However, smoking remains fairly stable among adults, predominantly among men, with gaps between men and women persisting since the early 2000s. Beyond the gender gap, social disparities in consumption remain significant, both among youth and adults. However, while the prevalence of smoking is no longer increasing, the prevalence of vaping is rising, which is a public health concern since some of these practices involve nicotine consumption. This also entails the risk of a “renormalization” of the act of smoking, a matter of concern for health authorities in France as in other European countries. The analysis concludes that the statistical information system and qualitative surveys need to be adapted to ensure a reliable monitoring of the situation, taking into account the rapid transformations of the market.Cet article fait le point sur les évolutions en matière de consommation de tabac et de produits de vapotage, en France, depuis une trentaine d’années, et les enjeux qu’elles soulèvent pour les pouvoirs publics, en termes de prévention et de prise en charge des conséquences sociosanitaires. Produit d’une analyse conjointe de Santé publique France (SpF) et de l’Observatoire français des drogues et des tendances addictives (OFDT), il montre d’abord un « tournant générationnel » dans la consommation de tabac et les représentations sociales de la cigarette depuis le milieu des années 2010, avec un recul marqué de l’expérimentation parmi les adolescents, qui est devenue à la fois moins courante et plus tardive, ce qui était un des objectifs des plans nationaux de réduction du tabagisme successivement mis en place depuis 2014. Le tabagisme reste néanmoins assez stable parmi les adultes, prédominant chez les hommes, avec des écarts entre hommes et femmes qui se maintiennent depuis le début des années 2000. Au-delà du différentiel de genre, les disparités sociales de consommation restent importantes, parmi les jeunes comme à l’âge adulte. Cependant, si la prévalence du tabagisme ne progresse plus, celle du vapotage augmente, ce qui constitue un point d’attention dès lors qu’une partie de ces pratiques induit une consommation de nicotine. Cela induit également le risque d’une « renormalisation » de l’acte de fumer, qui constitue un point de vigilance des autorités sanitaires, en France comme dans d’autres pays européens. L’analyse se conclut sur la nécessité de continuer à adapter le système d’information statistique et les enquêtes qualitatives pour permettre un suivi épidémiologique de la situation qui reste performant.
5
19-33
35
tobacco; tobacco use; nicotine; electronic cigarette; epidemiology
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
Mâle
adulte
adolescent
humains
Femelle
Dispositifs électroniques d'administration de nicotine
Fumer
produits du tabac
tabac
France

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Les puffs, révélateurs de l’indécision gouvernementale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172046
Basset B
Daimé P
10.3917/spub.pr1.0022
While the value of vaping is the subject of scientific debates, the arrival on the market of a marketing product, puffs, intended for adolescents is a new challenge for the health authorities. How can we prevent young people from entering into nicotine addiction without prohibiting the use of vaping by smokers in order to quit cigarettes?Alors que l’intérêt de la cigarette électronique fait l’objet de débats scientifiques, l’arrivée sur le marché d’un produit marketing, les puffs, destiné aux adolescents est un nouveau défi pour les autorités sanitaires. Comment prévenir l’entrée des jeunes dans la dépendance à la nicotine, sans interdire le recours au vapotage par les fumeurs qui souhaitent arrêter la cigarette ?
5
35-38
35
teenagers; e-cigarette; nicotine addiction; health and environmental challenge; marketing and health
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
adolescent
humains
Dispositifs électroniques d'administration de nicotine
gouvernement

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Éradiquer sans prohiber ? Évolutions internationales des politiques publiques de contrôle du tabac au XXIe siècle.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172047
Taiclet AF
10.3917/spub.pr1.0024
This article offers an analytical synthesis of international trends in public policies to regulate tobacco in the first quarter of the twenty-first century. It begins with a review of the densification of the repertoire of public action and the affirmation of a strategy that consists of encircling tobacco (designated as an enemy) and attacking it through a variety of material and symbolic tactics. Tobacco regulation is a constantly dynamic process, due to the intensity of the exchanges of blows between protagonists: these agonistic interactions are reflected in framing struggles that lead to a diversification of tobacco qualifications. Tobacco is thus framed as a health issue, but also as an environmental problem and a challenge for social justice. Finally, the article shows how, at the end of a quarter-century of diverse mobilizations, the gradual formulation of a paradigm shift is taking shape, in which the objective of public action is no longer simply to control tobacco, but to eliminate it as a commodity.Cet article propose une synthèse analytique des tendances internationales observables dans les politiques publiques de régulation du tabac dans ce premier quart du XXIe siècle. Il revient d’abord sur la densification du répertoire d’actions publiques et l’affirmation d’une stratégie consistant à encercler le tabac (désigné comme un ennemi) et à l’attaquer par le biais de différentes tactiques matérielles et symboliques. La régulation du tabac est un processus en mouvement permanent, du fait de l’intensité des échanges de coups entre protagonistes : ces interactions agonistiques se traduisent dans des luttes de cadrage qui entraînent une diversification des qualifications du tabac, comme problème sanitaire mais aussi environnemental et social. Enfin, l’article montre comment, à l’issue de ce quart de siècle de mobilisations diverses, s’esquisse la formulation progressive d’un changement de paradigme, où l’objectif de l’action publique ne serait plus seulement le contrôle du tabac mais sa disparition comme bien courant.
5
39-49
35
smoking; tobacco control; international policy landscape; endgame strategies; prohibition
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
politique publique

---
Fiction contre fiction.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172048
Ledun M
10.3917/spub.pr1.0027
5
5-6
35
03
Janvier
publication papier
Accès restreint
article de périodique

---
Dénormalisation du tabac et de son industrie par la société civile : mise en œuvre et évaluation de la campagne « Pouvoir de vivre » par l’ACT – Alliance contre le tabac.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172049
de Guiran E
Josseran L
Catellin M
10.3917/spub.235.0051
This article examines the “denormalization” approach, which has gradually gained ground in the field of tobacco control. This process encompasses a wide range of practices and aims to renew tobacco control by extending its scope beyond the usual individual and health considerations; it also considers smoking as a societal problem. This contribution illustrates the implementation of this approach, as embodied in France by the Alliance Contre le Tabac denormalization program launched in 2019, through campaigns addressing a diverse range of themes. The latest campaign, carried out in January 2023, demonstrates that smoking also exacerbates the social and economic difficulties of the most disadvantaged members of society. Its presentation illustrates the deployment of such a campaign, the methodology used, the tools mobilized, and the results obtained by carrying out a post-test.Cet article présente l’approche dite de dénormalisation, qui s’est progressivement imposée dans le champ de la lutte contre le tabac. Cette démarche regroupe un ensemble varié de pratiques et entend renouveler les méthodes de la lutte contre le tabac en élargissant sa portée au-delà des considérations individuelles et sanitaires habituelles ; elle envisage le tabagisme en tant que problématique sociétale. Cette contribution illustre la mise en œuvre de cette approche, incarnée en France par les campagnes de dénormalisation de l’Alliance Contre le Tabac depuis 2019. La dernière campagne réalisée en janvier 2023 démontre que le tabagisme, au-delà de son impact sanitaire, aggrave aussi les difficultés financières quotidiennes des personnes les plus modestes. La présentation de ce dispositif permet d’illustrer le déploiement de ce type de campagne, la méthodologie utilisée, les outils mobilisés et les résultats obtenus, grâce à la réalisation d’un post-test.
5
51-60
35
smoking; denormalization; tobacco; tobacco industry; public health
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
industrie du tabac
Fumer
France

---
Le tabac chauffé est-il un outil de réduction des risques ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172050
Thomas D
10.3917/spub.pr1.0023
Heated tobacco (HT), a new tobacco product, is presented by the tobacco industry as an effective and safe alternative to cigarettes. Even if the quantities of harmful compounds emitted by HT are lower than those found in cigarette smoke, this reduction in exposure cannot be equated with a reduction in risk. No study has provided evidence that switching from cigarettes to HT reduces the risk of tobacco-related diseases. HT cannot be considered as a cigarette cessation product and was even designed as a product to initiate or return to tobacco consumption. To promote this product, the tobacco industry essentially exploits the concept of harm reduction and, as such, tries in its commercial communication to create confusion between HT and electronic cigarettes, despite these two products having nothing in common. This promotion is based, on the one hand, on the data of internal studies in contradiction with those of independent studies, and, on the other, illegally, on social networks and communication in contradiction with the statements of regulation authorities. HT is a new lure offered by the tobacco industry, intended to maintain its profits in a world that is moving away from “traditional” cigarettes. It should be strictly advised against for both non-smokers and smokers.Le tabac chauffé (TC), nouveau produit du tabac, est présenté par l’industrie du tabac comme une alternative efficace et sûre à la cigarette. Même si les quantités de composés nocifs pour la santé émises par le TC sont inférieures à celles trouvées dans la fumée de cigarette, cette diminution d’exposition ne peut être assimilée à une réduction des risques. Aucune étude n’a apporté la preuve que le passage de la cigarette au TC réduisait le risque des maladies liées au tabac. Le TC ne peut pas être considéré comme un produit de sevrage de la cigarette et a même été conçu comme un produit pour entrer dans la consommation de tabac ou y revenir. Pour faire la promotion de ce produit, l’industrie du tabac exploite essentiellement le concept de réduction des risques et, à ce titre, essaie dans sa communication commerciale de créer la confusion entre le TC et la cigarette électronique alors que ces deux produits n’ont rien à voir. Cette promotion s’appuie, d’une part, sur les données d’études internes contradictoires avec celles d’études indépendantes, d’autre part, de façon illégale, sur les réseaux sociaux et une communication en contradiction avec les avis des autorités de régulation. Le TC est un nouveau leurre de l’industrie du tabac, destiné à assurer le maintien de ses profits dans un monde qui s’éloigne de la cigarette « traditionnelle ». Il doit être formellement déconseillé, tant aux non-fumeurs qu’aux fumeurs.
5
61-67
35
smoking; tobacco; heated tobacco product; electronic nicotine delivery system; harm reduction; tobacco industry; public health
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
réduction des dommages
Dispositifs électroniques d'administration de nicotine
Arrêter de fumer
communication
comportement en matière de santé

---
Tabac et précarité : l’enjeu central de l’accès aux soins.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172051
Delile JM
10.3917/spub.pr1.0025
La prévalence et la sévérité du tabagisme sont particulièrement élevées dans les populations en situation de précarité et font du tabagisme un déterminant essentiel des inégalités sociales de santé, du fait de son impact particulièrement catastrophique sur la santé de ces populations. La réduction générale du tabagisme, moins importante dans les populations défavorisées, contribue à accroître encore ces inégalités et le tabagisme a tendance à se concentrer dans les populations les plus vulnérables. Les relations entre tabac et précarité sont examinées en identifiant, sur la base d’une revue de la littérature, les principaux facteurs communs de vulnérabilité : stress et adversité sociale, auto-stigmatisation, faible sentiment d’auto-efficacité, fonction sociale du tabagisme, ambivalence de la demande, addictions associées, sévérité de la dépendance au tabac, éloignement des dispositifs d’aide et de soins… Une attention spécifique est prêtée à certaines conditions particulières : troubles mentaux, addictions (hors-tabac), mal-logement, détention, migrations. Sur cette base, des pistes d’actions sont proposées pour améliorer l’accès aux soins et leur efficacité chez les personnes concernées. Un accent particulier est porté sur la mobilisation des professionnels qui ont souvent tendance à négliger les questions de tabagisme au regard de la sévérité immédiate des problèmes à l’origine de la demande des personnes accueillies. Une offre d’accompagnement à la réduction des risques (vapotage notamment) semble particulièrement adaptée à la demande souvent ambivalente des personnes. L’importance du travail en réseau et de l’implication des CSAPA/CAARUD est également soulignée. Sur le plan systémique, tout ceci doit s’accompagner d’un plaidoyer politique pour réduire ces inégalités et déterminants sociaux de santé.
5
69-80
35
tobacco use disorder; precariousness; social and economic status; social determinants; harm reduction; mental health
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
Fumer
troubles mentaux
facteurs socioéconomiques
Arrêter de fumer
accessibilité des services de santé

---
Élaboration par méthode du consensus simple d’un outil d’aide au déclenchement d’un hélicoptère au SAMU 14.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172052
Hermilly M
Michel F
Hanouz JL
Macrez R
Aubrion A
Clanet R
10.3917/spub.235.0007
The main objective of this work was to develop a tool to assist the activation of a helicopter emergency medical service (HEMS) for the SAMU 14. We opted for a methodology based on “guidelines of good professional practice.” Simple consensus was used. A multidisciplinary working group (pilots, medical regulation assistants, doctors) was created. Subgroup meetings (pilots, medical regulation assistants, doctors) developed subparts of the tool. The assembly of the tool’s subparts was reviewed by the working group and then by an independent reading group. This work enabled the consensual creation of a tool to support the use of the helicopter emergency medical service (HEMS) for the SAMU 14. It is composed of maps, a protocol, and a written procedure of activation. This methodology by “simple consensus” allowed the development of a tool rationalizing the activation of the helicopter emergency medical service (HEMS) for the SAMU 14. It was the first work of this type within the SAMU 14. This simple and transposable methodology could be used in other emergency centers or for other multidisciplinary protocols.L’objectif principal de ce travail était la création d’un outil d’aide au déclenchement d’un SMUR héliporté au SAMU 14. Nous avons opté pour une méthodologie type « recommandations de bonnes pratiques professionnelles » (RBPP). Le consensus simple a été utilisé. Un groupe de travail multidisciplinaire (pilotes, assistant de régulation médicale [ARM], médecins) a été créé. Des réunions en sous-groupe (pilote, ARM et médecins) ont permis d’élaborer des sous-parties de l’outil. L’assemblage des sous-parties de l’outil a été relu par le groupe de travail puis par un groupe de lecture autonome et validé en réunion de service. Ce travail a permis la création consensuelle d’un outil d’aide à l’emploi du vecteur héliporté en SMUR primaire au sein du SAMU 14. Il est composé de cartes, d’une fiche réflexe et d’une procédure écrite de déclenchement. Cette méthodologie par consensus simple a permis la création d’un outil rationalisant le déclenchement du vecteur héliporté pour le SAMU 14. Il s’agissait du premier travail de ce type au SAMU 14. Cette méthodologie simple et transposable pourrait être utilisée dans d’autres centres 15 ou pour d’autres protocoles multidisciplinaires.
5
7-12
35
guidelines of good professional practice; simple consensus; working group; multidisciplinary; tool; helicopter; helicopter emergency medical service
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
ambulances aéroportées
consensus
véhicules de transport aérien
services des urgences médicales
auxiliaires de santé

---
Liens entre le statut tabagique et la situation vis-à-vis de l’emploi : analyse transversale de la cohorte CONSTANCES.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172053
El Haddad R
Renuy A
Wiernik E
Goldberg M
Zins M
Airagnes G
10.3917/spub.pr1.0026
This study aims to estimate the prevalence of tobacco use in 2017 and 2019 in the French population covered by the Régime Général d’Assurance Maladie according to employment status. From the French national CONSTANCES cohort, 18,008 randomly recruited volunteers aged between 18 and 69 years, affiliated to the Régime Général d’Assurance Maladie and enrolled in 2017, were included in the analysis. The prevalence of tobacco use according to employment status was estimated. Estimates of these prevalence data were calculated in 2017 and 2019 after correction for selection bias at inclusion and non-response at follow-up. In 2019, smoking prevalence was higher among unemployed people (29.2% among men and 20.7% among women) than among employed people (16.5% among men and 13.8% among women). Smoking prevalence was highest among those not in work for health reasons (38.5% among men and 35.8% among women). Smokers were more likely to be unemployed than non-smokers (OR 2.63 [95% confidence interval (CI): 1.79; 3.85] in men and OR 1.55 [95% CI: 1.08; 2.22] in women). Among men, the prevalence of employed people among light smokers ( 10 cigarettes/day) significantly decreased between 2017 (87.1%) and 2019 (74.8%). These results underline the importance of reinforcing smoking prevention campaigns among the unemployed, particularly for health reasons.Estimer les prévalences d’usage de tabac en 2017 et en 2019 en population française couverte par le Régime Général d’Assurance Maladie en fonction du statut vis-à-vis de l’emploi. À partir d’un échantillon de 18 008 volontaires inclus en 2017 dans CONSTANCES, une cohorte nationale en population générale française ayant recruté de manière aléatoire des volontaires de 18-69 ans affiliés au Régime Général d’Assurance Maladie, les prévalences d’usage du tabac en fonction de du statut vis-à-vis de l’emploi ont été estimées en 2017 et en 2019 après correction pour les biais de sélection à l’inclusion et de non-réponse au suivi. En 2019, la prévalence du tabagisme était plus élevée chez les actifs inoccupés (29,2 % chez les hommes et 20,7 % chez les femmes) par rapport aux actifs occupés (16,5 % chez les hommes et 13,8 % chez les femmes). La prévalence du tabagisme la plus élevée concernait les personnes sans activité professionnelle pour raisons de santé (38,5 % chez les hommes et 35,8 % chez les femmes). Les fumeurs étaient plus à risque d’être actifs inoccupés comparativement aux non-fumeurs (OR 2,63 [95 % Intervalle de confiance [IC] : 1,79 ; 3,85] chez les hommes et OR 1,55 [95 % IC : 1,08 ; 2,22] chez les femmes). Chez les hommes, la prévalence d’actifs occupés parmi les petits fumeurs ( 10 cigarettes/jour) a baissé entre 2017 (87,1 %) et 2019 (74,8 %). Ces analyses soulignent l’importance d’intensifier les campagnes de prévention sur le tabagisme parmi les actifs inoccupés et les inactifs, en particulier pour raisons de santé.
5
81-94
35
tobacco use; employment; unemployment; french population
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
Mâle
humains
Femelle
adolescent
jeune adulte
adulte
adulte d'âge moyen
sujet âgé
études transversales
emploi
Usage de tabac
Fumer
chômage
prévalence

---
Les facteurs contextuels pour comprendre l’hétérogénéité des résultats d’une politique d’exemption du paiement des soins au Tchad.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38172054
Manoufi D
Ridde V
10.3917/spub.235.0095
Chad has one of the highest maternal and infant mortality rates in the world. Efforts to reduce these rates have led to the introduction of fee exemption and community involvement initiatives to further encourage the use of health services. Despite the introduction of these initiatives, inequalities in access to and use of health facilities persist. The aim of this study is to understand why and how the same action, implemented in a quasi-homogeneous way, produced contrasting results in different health centers. A multiple, contrasting case study was used to analyze the outcomes of pediatrics consultations and deliveries in four health centers in the Bénoye and Beinamar districts. Data were collected through individual interviews (n 26) and focus groups (n 22) with women beneficiaries, community health workers, and health care providers. The qualitative software QDA Miner was used to process the data. The study revealed that the organizational and managerial capacities of the providers and community actors would explain the heterogeneity of the results observed. Contextual factors such as the remoteness of services or the impassability and dangerousness of roads accentuated the disparities in the results observed. The results of this study show that human and contextual factors would explain the heterogeneity of the observed effects.Le Tchad a l’un des taux de mortalité maternelle et infantile les plus élevés au monde. Les efforts visant à réduire ces taux ont conduit à la mise en place d’une politique d’exemption du paiement des soins, associée à l’implication des communautés pour encourager l’utilisation des services. Malgré l’introduction de cette initiative, des inégalités dans l’accès et l’utilisation des établissements de santé persistent. L’objectif de cette étude est de comprendre pourquoi et comment cette politique d’exemption, mise en œuvre de manière quasi homogène, a donné des résultats contrastés dans plusieurs centres de santé. Une étude de cas multiples contrastés a été utilisée pour analyser les résultats des consultations pédiatriques et des accouchements dans quatre centres de santé des districts de Bénoye et Beinamar. Les données ont été recueillies lors des entretiens individuels (n 26) et des groupes de discussion (n 22) auprès des femmes bénéficiaires, des agents de santé communautaire et des prestataires de soins. Le logiciel QDA Miner a été utilisé pour traiter les données. L’étude a révélé que les capacités organisationnelles et managériales des prestataires et des acteurs communautaires expliqueraient l’hétérogénéité des résultats observés. Des facteurs contextuels tels que l’éloignement des services ou l’impraticabilité et la dangerosité des routes ont accentué les disparités des résultats observés. Dans la mise en place des politiques de santé, il est important de tenir compte des facteurs humains et contextuels, car ils participent à l’explication de l’hétérogénéité des effets observés et renforcent la pertinence de ce type d’études.
5
95-119
35
heterogeneity of effects; contextual factors; health service utilization; community health; qualitative study; chad
03
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
Femelle
enfant
grossesse
Tchad
politique de santé
Groupes de discussion
établissements de santé
mortalité infantile
services de santé maternelle

---
La Commission de la transparence de la Haute Autorité de santé.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38176970
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00485-X
Lengliné E
10.1016/j.bulcan.2023.12.002
The Transparency Committee (TC) in France plays a crucial role in the evaluation of post-market authorization (MA) drugs for reimbursement by the social security system. Although its organization has evolved since its creation, the principle of its existence has persisted since the establishment of the social security system. The TC, transitioning from the Medicines Agency to the Haute Autorité de santé in 2005, focuses on the medico-scientific evaluation of drugs, influencing decisions on reimbursement eligibility and price negotiations. It assesses the benefit and added medical value of drugs. Comprising experts with no conflicts of interest with pharmaceutical companies, the TC conducts a scientific evaluation of submissions by pharmaceutical laboratories. Recently, it has also been involved in evaluating requests for early access authorization prior to MA.
2
228-234
111
drugs; evaluation; health technology assessment; industrie pharmaceutique; médicament; pharmaceutical industry; régulation; évaluation
03
Février
S0007-4551(23)00485-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
préparations pharmaceutiques
humains
France

---
Corrigendum à l’article « Nouvelles AMMs européenne : utilisation du zanubrutinib en monothérapie dans le traitement de la leucémie lymphoïde chronique » [Bull Cancer 2023;110:744–745].
2024
http://www.ncbi.nlm.nih.gov/pubmed/38182437
Thiam M
Cavalieri D
10.1016/j.bulcan.2023.12.001
04
Janvier
S0007-4551(23)00483-6
publication avant impression
Accès restreint
erratum publié

---
Regards croisés des proches aidants, des professionnels de la santé et des prestataires de soutien concernant les enjeux de partenariat en psychiatrie adulte.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38182537
Alves M
Skuza K
Coloni-Terrapon C
Lê Van K
Wenger D
Rexhaj S
10.3917/rsi.154.0013
AbstractText Label CONTEXT Family caregivers play an essential role in the continuity of care for patients with mental health problems. However, the lack of consideration for their role and difficulties in their collaboration with health professionals impact their involvement. /AbstractText AbstractText Label OBJECTIVE The purpose of this study is to identify the issues underlying the family-professional partnership. /AbstractText AbstractText Label METHOD A qualitative and exploratory study is used to collect data from providers of support services, family caregivers of patients with psychiatric disorders, and mental health professionals. Semi-structured interviews and focus groups conducted from October 2017 to August 2018 were analyzed to determine key issues surrounding this partnership. /AbstractText AbstractText Label RESULTS A total of thirty-two family caregivers, nine healthcare professionals, and eleven providers participated in the study. The central concerns related to the partnership are information, continuity of care, and the relationship between patients, family members, and professionals. The relational dimension appears to be an important element for all three groups of participants, who nevertheless point out difficulties with regard to their positioning in this tripartite relationship. /AbstractText AbstractText Label DISCUSSION/CONCLUSION In the context of the current healthcare system, the concept of partnership creates obstacles to family caregivers being able to contribute their expertise while feeling recognized by the other actors. /AbstractText
3
13-28
154
caregivers; partnership; psychiatry; collaboration; care
05
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
adulte
humains
aidants
personnel de santé
psychiatrie
émotions
famille

---
La socioesthétique auprès des sans-abri : agir sur le corps et l’identité des « grands marginaux ».
2024
http://www.ncbi.nlm.nih.gov/pubmed/38182538
Besozzi T
10.3917/rsi.154.0029
This article explores the relevance of the psycho-corporal mediation that interventions based on social aesthetics allow when working with the homeless, particularly regarding the specific nature of their identities and bodies. Based on an ethnographic survey conducted in an experimental shelter for extremely marginalized people (named the “Integration Village”), we detail the health, body, and identity issues related to this type of care. The scientific literature and the social aestheticians we interviewed also indicate that the bodily and psychological dimensions of this type of treatment are closely intertwined. After specifying the modalities for the implementation of social aesthetics sessions in the Village, we focus on the perceptions and expectations of homeless patients toward this potential care approach. Finally, we observe the effects of a social aesthetics-based approach on homeless individuals in order to test the hypothesis that socio-aesthetic care is beneficial to them (at different levels and in different ways), both in terms of their relationship with their bodies and their self-esteem.
3
29-42
154
homeless; social aesthetics; relation to the body; identity; ethnography
05
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
anthropologie culturelle
concept du soi

---
Élaboration d’un outil d’évaluation des compétences en stage des étudiants infirmiers en pratique avancée, mention psychiatrie et santé mentale à partir d’une méthode Delphi.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38182539
Mayen S
Roman C
Cermolacce M
Colson S
10.3917/rsi.154.0043
AbstractText Label INTRODUCTION In France, advanced practice for psychiatric and mental health nurses has been developing since 2019. The acquisition of clinical skills by advanced practice nursing students requires monitoring and evaluation. This article outlines the process for creating an internship logbook. /AbstractText AbstractText Label OBJECTIVE To develop and verify a tool for assessing the skills of advanced practice nursing students specializing in psychiatry and mental health during the internship stage. /AbstractText AbstractText Label METHOD The Delphi method described by Hasson was used, with the aim of obtaining a consensus of over 80% of the experts consulted. /AbstractText AbstractText Label RESULTS A panel of ten experts, all internship tutors at partner healthcare establishments of Aix Marseille University, was consulted twice. The internship logbook was composed of 68 items. /AbstractText AbstractText Label DISCUSSION This tool is the product of a multidisciplinary process including nurses and psychiatric nurses. It can be adapted to a variety of learning environments and helps tutors track the acquisition of clinical skills during the internships, both through external and self-assessment. /AbstractText AbstractText Label CONCLUSION A new Delphi consultation will foster uptake of this tool. Advanced practice nurses in psychiatry and mental health will be included in the group of experts. /AbstractText
3
43-54
154
internship tutoring; advanced practice nursing; educational measurement; clinical competence; professional skills
05
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
élève infirmier
internat et résidence
santé mentale
méthode Delphi
psychiatrie

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La prise de décision infirmière : l’importance de nommer une compétence peu visible.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38182540
Cartron E
Quindroit P
10.3917/rsi.154.0005
3
5
154
05
Janvier
publication papier
Accès restreint
article de périodique
humains
prise de décision
soins

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Les connaissances infirmières mobilisées en phase aigüe de l’accident vasculaire cérébral : une étude exploratoire qualitative descriptive.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38182541
Setnikar A
Lecordier D
10.3917/rsi.154.0055
AbstractText Label INTRODUCTION Strokes represent a major public health issue in which nurses are involved, both in care and in research. The literature reveals a description of their activities in treating the disease and the altered functions in which it results, as well as in managing the experience of the sufferer. The aim of this work was to describe the knowledge upon which nurses draw when caring for patients in the acute phase of stroke. /AbstractText AbstractText Label METHODS This exploratory qualitative descriptive multicentric survey was carried out via non-directive interviews with nurses working in neurovascular units. Thematic qualitative analysis was used to describe their activities and to highlight the knowledge and skills used. /AbstractText AbstractText Label RESULTS The results show that the nurses express themselves with ease when discussing their medical knowledge, and with more difficulty concerning knowledge from the human, social, and nursing sciences. However, they often combine this knowledge in a nursing perspective. /AbstractText AbstractText Label DISCUSSION This work opens up prospects with regard to supporting the nursing knowledge already leveraged and developing the nursing knowledge (concepts and theory of care) relevant to the particular context of strokes. The results also encourage a reflective analysis of nurses’ experience. /AbstractText
3
55-69
154
stroke; nursing care; knowledge; clinical skills; nursing science
05
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
accident vasculaire cérébral
Savoir
santé publique
recherche qualitative

---
Qu’est-ce qui se rétablit ? Réflexion sur la place de la perception, du temps et de la norme dans le rétablissement en santé.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38182542
Bastiani F
10.3917/rsi.154.0006
The notion of recovery is frequently evoked in healthcare, but it carries with it a number of ambiguities: do we envisage a return to a state that preceded the illness, or a way of composing a new way of living based on the illness? In order to think more precisely about recovery, this paper proposes to take a philosophical look at the notion of norm and to develop its importance through an approach to time, body and world. This analysis will make it possible to clarify the existential aspects involved in health recovery, and to describe the issues at stake in the care relationship in terms of these dimensions of subjective experience.
3
6-12
154
recovery; standard of care; normativity; lived experience; professional-patient relations
05
Janvier
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
perception du temps
récupération fonctionnelle

---
Qu’est-ce que 2023 aura permis de changer dans nos pratiques en cancérologie ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38184423
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00486-1
Bay JO
Auberger B
Bouleuc C
Cohen R
Delom F
Firmin N
Gandemer V
L'Allemain G
Magne N
De Nonneville A
Orbach D
Pellier I
Rodrigues M
Wislez M
pour le comité de rédaction du Bulletin du Cancer
10.1016/j.bulcan.2023.12.003
In 2023, the improvement of our therapeutic management has largely taken shape. The aim of our article is to highlight the major advances that will change our practices. These are not only in the field of treatment, but also in the improvement of supportive care. Here, we present these new developments organ by organ, cancer by cancer. You can read everything or concentrate on the cancers that are your areas of expertise. But this exhaustiveness should be representative of our current state of progress.
1
18-32
111
actualités 2023 en cancérologie; new treatments in oncology; nouveaux traitements; updates in 2023
05
Janvier
S0007-4551(23)00486-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
tumeurs
oncologie médicale

---
Éditorial.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38185513
https://linkinghub.elsevier.com/retrieve/pii/S0294-1260(23)00166-8
Bustamante K
10.1016/j.anplas.2023.12.001
1
1
69
Janvier
S0294-1260(23)00166-8
publication papier
Accès restreint
éditorial

---
Le Collège national des enseignants de cancérologie (CNEC) : missions, organisation et projets.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38185534
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00488-5
Huguet F
Tlemsani C
Pierga JY
Curtit E
Deluche E
Domblides C
Guimbaud R
Laprie A
Marchal F
Massard C
Spano JP
10.1016/j.bulcan.2023.12.004
The National College of Cancerology Teachers (CNEC) was created in September 1986. Its missions are to develop the teaching of oncology, to promote educational actions in the discipline, to participate in the development of teaching content and the definition of curricula and the control of knowledge for the training of medical students and specialists, to develop and validate educational documents relating to the above teaching, to ensure the representation of oncology teaching to of the National University Council (CNU) and administrative authorities, to ensure and coordinate relations with other university disciplines, scientific societies, national, European, and international professional groups, and to contribute to the development of research in the discipline. The current office was elected in September 2022 for three years.
2
133-141
111
education; enseignement; fst; medical studies; oncologie; oncology; reform; réforme; simulation; études médicales
06
Février
S0007-4551(23)00488-5
publication avant impression
Accès restreint
éditorial
résumé en anglais
humains
universités
programme d'études
étudiant médecine

---
Désarticulation scapulo-thoracique, une conséquence d’un échec de traitement traditionnel chez une adolescente: à propos d’un cas.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38188885
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10768548
https://www.panafrican-med-journal.com/content/article/46/49/full/
Tapsoba WT
Ouédraogo SMF
Béré B
Ganamé SNO
Koundia T
Zampou O
Isso O
Emile B
10.11604/pamj.2023.46.49.41650
Scapulothoracic dissociation due to a trauma is exceptional. The purpose of this study was to share our experience with a case of scapulothoracic dissociation and to explain the advantages of our approach. We report the case of a 12-year-old right-handed schoolgirl admitted to hospital with a blunt trauma to the right thoracic limb complicated by infection after a week of traditional treatment (massage, bandaging with reed splints). Surgical neck fracture of the right humerus complicated by wet gangrene of the entire limb and severe anaemia was diagnosed. Blood transfusion, triple antibiotic therapy and scapulohumeral disarticulation were required. Progressive excision of necrotic tissue followed by scapulectomy (day 24) for scapular necrosis made it possible to sterilise the site and to perform a skin graft (day 43). The patient was discharged after 2 months. Physiotherapy was combined with psychological treatment and the patient had a simple post-operative course during the 7-month follow-up period. Failure of conventional treatment for limb fractures can be life-threatening and cause severe sequelae.La désarticulation scapulo-thoracique pour une pathologie traumatique est exceptionnelle. La présentation de ce cas clinique vise à partager notre expérience à propos d'un cas de désarticulation scapulo-thoracique et situer l'intérêt d'une telle indication. Il s'est agi d'une patiente de 12 ans, de latéralité droite, scolarisée, qui a été hospitalisée pour traumatisme fermé du membre thoracique droit compliqué d'une infection après une semaine de traitement traditionnel (massage, bandage avec attelles en roseau). Le diagnostic de fracture du col chirurgical de l'humérus droit compliquée d'une gangrène humide de tout le membre et d'une anémie sévère, a été posé. Une transfusion sanguine, une triple antibiothérapie et une désarticulation scapulo-humérale ont été nécessaires. Une excision progressive de tissus nécrotiques puis une scapulectomie (à J24) pour nécrose scapulaire ont permis d'aseptiser le foyer et de réaliser une greffe cutanée (à J43). La patiente, sortie après 2 mois d'hospitalisation, avec un suivi conjoint en psychologie et en kinésithérapie, a présenté des suites opératoires simples sur un recul de 7 mois. L'échec du traitement traditionnel des fractures de membre peut mettre en jeu le pronostic vital et occasionner de graves séquelles.
49
46
disarticulation; case report; child; gangrene; scapulo-thoracic
PAMJ-46-49
publication électronique
Accès restreint
présentations de cas
résumé en anglais
Femelle
adolescent
humains
enfant
médecine
arthrodèse
désarticulation
évolution de la maladie
main

---
RE: “Conversation between a clinical biologist and an artificial intelligence on prostate cancer biomarkers”.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38189337
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2023.1849
Daungsupawong H
Wiwanitkit V
10.1684/abc.2023.1849
6
660-661
81
24
Février
abc.2023.1849
publication avant impression
Accès restreint
article de périodique
Mâle
humains
prostate
communication
tumeurs

---
La révision de la loi de bioéthique, deux ans après : grands principes et conséquences pour la pratique au laboratoire de biologie de la reproduction.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38189359
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2023.1847
Rivet-Danon D
Ly A
Prades-Borio M
Berthaut I
Ogouma-Aworet L
Panissard C
Bachelot G
Lévy R
Dupont C
Sermondade N
10.1684/abc.2023.1847
Since 1994, in France, bioethics law has set the regulatory framework for Medically Assisted Reproduction (MAR). The latest revision of the law of August 2, 2021, is characterized by major upheavals in the field of MAR and intervenes in several areas: the purpose and conditions to access to MAR, access to origins in the case of gamete or embryo donation, and gametes cryopreservation without medical indication. Indeed, the law authorizes, because of a strong societal demand, the extension of sperm donation to couples of women and unmarried women, as well as the possibility for any person to preserve his/her gametes if he/she meets the age criteria defined by decree. Finally, the law opens the possibility for people born following gamete or embryo donation to have access, from their 18th anniversary, to identifying and/or non-identifying data. These new measures have led to a very important number of MAR requests to fertility and donation centers, and have required the implementation of new circuits in order to harmonize care, without discrimination or prioritization.
6
621-627
81
anonymity; assisted reproductive technologies; bioethics law; gamete donation; sperm donation
24
Février
abc.2023.1847
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Mâle
Femelle
techniques de reproduction assistée
mise à disposition d'embryon
sperme
bioéthique
biologie

---
Un bilan alarmant : un plasma sanglant !
2024
http://www.ncbi.nlm.nih.gov/pubmed/38189363
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2023.1850
Labasque J
Marchand D
Lhomme C
Lavisse J
Maboudou P
Grzych G
10.1684/abc.2023.1850
A 35-year-old patient with a metabolic pathology was hospitalized for programmed fibroscopy under general anesthesia for investigation and management of portal hypertension. Following the operation, he showed signs of sepsis and was transferred to intensive care unit. Biological analyzes carried out and generated automaton alarms for certain parameters. A visual check of the appearance of the sample revealed an unusual color of plasma. Additional informations obtained from the clinical department did not provide any explanation for this coloration. Additional assays confirmed an overdose of vitamin B12 related to the treatment of his pathology and which is responsible for the interference observed. Hence the interest of checking the reaction curves in the event of suspected interference and, if necessary, of making dilutions in order to reduce the effects on the biological assays.
6
653-656
81
biochemistry; cobalamin; colorimetric methods; interference; spectrophotometry
24
Février
abc.2023.1850
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
vitamine B12
Mâle
humains
adulte
vitamine B12

---
Découverte d’un phénotype érythrocytaire rare suite à une difficulté de groupage : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38189423
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/abc.2023.1848
Aissa W
Chouaieb S
Bellil N
Kaabi H
Hmida S
10.1684/abc.2023.1848
ABO typing is essential for preventing ABO incompatibility transfusion reactions. Discrepancy exists when reactions in forward grouping do not match with reverse grouping. Any discrepancies reported should be investigated so that correct blood group is reported minimizing the chances of transfusion reaction. The most common causes of ABO discrepancy are cold autoantibodies and missing serum reactivity. We report a rare alloantibody anti-PP1Pk discovered during the resolution of a grouping difficulty with a positive control. Anti-PP1Pk is associated with hemolytic transfusion reactions. In our observation, we were faced with transfusional impasse because of the unavailability of a national rare blood bank or a compatible donor on the registry of individuals with a rare blood phenotype.
6
645-648
81
anti-pp1pk; blood group discrepancy; blood grouping; rare blood group
24
Février
abc.2023.1848
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
système ABO de groupes sanguins
humains
système ABO de groupes sanguins
transfusion sanguine
groupage sanguin et épreuve de compatibilité croisée
phénotype
donneurs de tissus

---
Quelle réponse apporter à un refus obstiné de soins lors de l’accouchement ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38190966
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00004-7
Lepercq J
Khoury L
Marcel P
Tsatsaris V
Goffinet F
10.1016/j.gofs.2023.12.009
Our team was confronted with a situation of stubborn refusal of care, including the indication of a cesarean section for an adult patient able to express her wishes. This refusal was formulated during pregnancy follow-up, during the discussion of the birth plan and during delivery, the patient having accepted the indication of a possible emergency cesarean section under general anesthesia only in the occurrence of severe fetal heart rate abnormalities. The impasse forced caregivers to violate the rules of good clinical practice, which indicated the performance of a cesarean section, and to wait for a complication to arise in order to be able to act, taking the risk of intervening too late. This situation has led to direct risks to the health of the mother and the unborn child, without putting the life of either of them in imminent danger. Finally, the time devoted to this patient in a tense organization was to the detriment of the care of other patients.
2
109-113
52
refus de soins; refusal of care; accouchement; cesarean delivery; césarienne; delivery; grossesse; medicolegal; médicolégal; pregnancy
06
Février
S2468-7189(24)00004-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
adulte
grossesse
humains
Femelle
césarienne
prise en charge prénatale
anesthésie générale
Refus du traitement

---
Actualisation des indications et des techniques de prise en charge du lymphœdème après chirurgie du cancer du sein.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38190967
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00001-1
Azuar AS
Uzan C
Mathelin C
Vignes S
10.1016/j.gofs.2023.12.008
AbstractText Label OBJECTIVES Upper limb lymphedema secondary to breast cancer treatment is the leading cause of lymphedema in France. Despite improved surgical practices and de-escalation of radiotherapy, the risk of lymphedema after breast cancer still affects 5-20% of patients, with this variation depending on the measurement method used and the population studied. Lymphedema has a negative impact on quality of life and body image, and their possible occurrence remains a major concern for all women treated for breast cancer. The Sénologie Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF) asked four specialists in breast surgery or lymphology to prepare a summary on the prevention, medical and surgical management of lymphedema after breast cancer treatment, and to discuss the medical and surgical innovations currently being evaluated. /AbstractText AbstractText Label METHODS This synthesis was based on national and international guidelines on the management of upper limb lymphedema after breast surgery and a recent review of the literature focusing on the years 2020-2023. /AbstractText AbstractText Label RESULTS From a preventive point of view, the restrictive instructions imposed for a long time (reduction in physical activity or the carrying of loads, air travel, exposure to the sun or cold, etc.) have altered patients' quality of life and should no longer be recommended. A good understanding of risk factors enables us to target preventive actions. Examples include obesity, a sedentary lifestyle, axillary clearance, radiotherapy of the axillary fossa in addition to axillary clearance, total mastectomy, taxanes or anti-HER-2 therapies in the adjuvant phase. Resumption of physical activity, minimally invasive axillary surgery, de-escalation of radiotherapy and breast-conserving surgical procedures have all demonstrated their preventive value. When lymphedema does occur, early management, through complete decongestive physiotherapy, can help reduce its volume and prevent its long-term worsening. /AbstractText AbstractText Label CONCLUSION Surgical (lymph node transplants, lympho-vascular anastomoses) and medical (prolymphangiogenic growth factors) approaches to lymphedema treatment are numerous, but require long-term evaluation of their efficacy and adverse effects. /AbstractText
3
142-148
52
breast cancer; compression; drainage; lymphedema; microsurgery
06
Mars
S2468-7189(24)00001-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Femelle
tumeurs du sein
mastectomie
qualité de vie
région mammaire
lymphoedème
lymphoedème

---
Peut-on surseoir au curage axillaire en cas de carcinome mammaire invasif avec envahissement ganglionnaire ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38190968
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00003-5
Brousse S
Lafond C
Schmitt M
Guillermet S
Molière S
Mathelin C
10.1016/j.gofs.2023.12.010
AbstractText Label OBJECTIVES The indications and modalities of breast and axillary surgery are undergoing profound change, with the aim of personalizing surgical management while avoiding over-treatment. To update best practices for axillary surgery, four questions were selected by the Senology Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF), focusing on 1) the definition and evaluation of targeted axillary dissection (TAD) techniques, 2) the possibility of surgical de-escalation in case of initial lymph node involvement while performing initial surgery, 3) in case of surgery following neo-adjuvant systemic therapy (NAST), 4) contraindications to de-escalation of axillary surgery to allow access to particular adjuvant systemic therapies. /AbstractText AbstractText Label METHODS The Senology Commission based its responses primarily on an analysis of the international literature, clinical practice recommendations and national and international guidelines. /AbstractText AbstractText Label RESULTS 1) TAD is a technique that combines excision of clipped metastatic axillary node(s) and the axillary sentinel lymph nodes (ASLNs). The detection rate and sensitivity are increased but it still needs to be standardized and practices better evaluated. 2) TAD represents an alternative to axillary clearance in cases of metastatic involvement of a single node that can be resected. 3) Neither TAD nor ASLN alone is recommended in France after NAST outside of clinical trials, although it is used in several countries in cases of complete pathological response in the lymph nodes, and when at least 3 lymph nodes have been removed. 4) As some adjuvant targeted therapies are indicated in cases of lymph node invasion of more than 3 lymph nodes, the place of TAD in this context remains to be defined. /AbstractText AbstractText Label CONCLUSION Axillary surgical de-escalation can limit the morbidity of axillary clearance. Having proved that TAD does not reduce patient survival, it will most probably replace axillary clearance in well-defined indications. This will require prior standardization of the method and its indications and contraindications, particularly to enable the use of new targeted therapies. /AbstractText
3
132-141
52
axillary lymph node dissection; breast cancer; cancer du sein; chirurgie; curage axillaire; dissection axillaire ciblée; ganglion sentinelle; sentinel lymph node; surgery; targeted axillary dissection
06
Mars
S2468-7189(24)00003-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Femelle
lymphadénectomie
noeuds lymphatiques
tumeurs du sein
région mammaire
association thérapeutique

---
Les actualités en génétique oncologique mammaire pour la population féminine et masculine.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38190969
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00002-3
Taris N
Luporsi E
Osada M
Thiblet M
Mathelin C
10.1016/j.gofs.2023.12.007
AbstractText Label OBJECTIVES Breast oncology genetics emerged almost 30 years ago with the discovery of the BRCA1 and BRCA2 genes. The evolution of analytical practices has progressively allowed access to tests whose results now have a considerable impact on the management of both female and male breast cancers.The Sénologie Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF) asked five specialists in breast surgery, oncology and oncological genetics to draw up a summary of the oncogenetic testing criteria used and the clinical implications for the female and male population of the test results, with or without an identified causal variant. In the case of proven genetic risk, surveillance, risk-reduction strategies, and the specificities of surgical and medical management (with PARP inhibitors in particular) were updated. /AbstractText AbstractText Label METHODS This summary was based on national and international guidelines on the monitoring and therapeutic management of genetic risk, and a recent review of the literature covering the last five years. /AbstractText AbstractText Label RESULTS Despite successive technical developments, the probability of identifying a causal variant in a situation suggestive of a predisposition to breast and ovarian cancer remains around 10% in France. The risk of breast cancer in women with a causal variant of the BRCA1, BRCA2, PALB2, TP53, CDH1 and PTEN genes is estimated at between 35% and 85% at age 70. The presence of a causal variant in one of these genes is the subject of different recommendations for men and women, concerning both surveillance, the age of onset and imaging modalities of which vary according to the genes involved, and risk-reduction surgery, which is possible for women as soon as their risk level exceeds 30% and remains exceptionally indicated for men. In the case of breast cancer, PARP inhibitors are a promising new class of treatment for BRCA germline mutations. /AbstractText AbstractText Label CONCLUSION A discipline resolutely focused on understanding molecular mechanisms, screening and preventive medicine/surgery, oncology genetics is currently also involved in new medical/surgical approaches, the long-term benefits/risks of which will need to be monitored. /AbstractText
3
149-157
52
brca; breast canceroncog; enetics; predisposition; risk-reducing mastectomy
06
Mars
S2468-7189(24)00002-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique
Femelle
humains
Mâle
sujet âgé
prédisposition génétique à une maladie
tumeurs du sein
tumeurs du sein
tumeurs du sein
gène BRCA2
facteurs de risque

---
Évaluation de la structure factorielle et des qualités psychométriques de l'Échelle de Fatigue Pandémique parmi la population adulte québécoise.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38193199
https://journals.sagepub.com/doi/10.1177/07067437231223331?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub 0pubmed
Marleau JD
Landaverde E
Généreux M
10.1177/07067437231223331
AbstractText Label OBJECTIVE The objective of the study is to evaluate the factorial structure and the psychometric qualities of the Pandemic Fatigue Scale among the Quebec adult population. /AbstractText AbstractText Label METHOD The data analyzed come from a web survey conducted in October 2021 among 10 368 adults residing in Quebec. The scale's factor structure and invariance by gender, age and language used to complete the questionnaire were tested using confirmatory factor analyses. Convergent and divergent validity were also assessed. Finally, the reliability of the scale was estimated from the alpha and omega coefficients. /AbstractText AbstractText Label RESULTS The analyzes suggest the presence of a bidimensional structure in the sample of Quebec adults with informational fatigue and behavioral fatigue. The invariance of the measure is noted for sex, for age subgroups and for the language used for the questionnaire. The results of convergent and divergent validity provide additional evidence for the validity of the scale. Finally, the reliability of the scale scores is excellent. /AbstractText AbstractText Label CONCLUSION The results support the presence of a bidimensional structure as in the initial work of Lilleholt et al. They also confirm that the scale has good psychometric qualities and that it can be used among the adult population of Quebec. /AbstractText AbstractText Label OBJECTIF L’objectif de l’étude est d’évaluer la structure factorielle et les qualités psychométriques de l’Échelle de Fatigue Pandémique parmi la population adulte québécoise. /AbstractText AbstractText Label MÉTHODE Les données analysées proviennent d’une enquête Web réalisée en octobre 2021 auprès de 10 368 adultes résidant au Québec. La structure factorielle de l’échelle et l’invariance selon le sexe, l’âge et la langue utilisée pour le questionnaire ont été testées à l’aide d’analyses factorielles confirmatoires. La validité convergente et divergente ont aussi été évaluées. Enfin, la fidélité de l’échelle a été estimée à partir des coefficients alpha et oméga total. /AbstractText AbstractText Label RÉSULTATS Les analyses suggèrent la présence d’une structure bidimensionnelle dans l’échantillon d’adultes québécois avec la fatigue informationnelle et la fatigue comportementale. L’invariance de la mesure est notée pour le sexe, pour les groupes d’âge et pour la langue utilisée pour la complétion du questionnaire. Les résultats de la validité convergente et divergente apportent des preuves supplémentaires à la validité de l’échelle. Enfin, la fidélité des scores de l’échelle est excellente. /AbstractText AbstractText Label CONCLUSION Les résultats appuient la présence d’une structure bidimensionnelle comme dans les travaux initiaux de Lilleholt et coll. Ils permettent également d’affirmer que l’échelle possède de bonnes qualités psychométriques et qu’elle peut être utilisée parmi la population adulte québécoise. /AbstractText
7067437231223331
quebec adults; adultes québécois; analyse factorielle exploratoire et confirmatoire.; behavioral fatigue; exploratory and confirmatory factor analysis; fatigue comportementale; fatigue informationnelle; fatigue pandémique; informational fatigue; pandemic fatigue; validity and reliability; validité et fidélité
09
Janvier
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Doit-on prendre en compte le stress informationnel de l’oncologue médical ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38199834
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00444-7
Penel N
Mailliez A
Pannier D
Ducrocq C
10.1016/j.bulcan.2023.11.008
Information overload, informational stress and its deleterious consequences constitute a subject of growing interest in the way of work. This is quite well documented among anesthesiologists. Studies have also been carried out on cancer patients or on the general public in terms of cancer prevention. After having defined the concepts and the consequences, we hypothesize the presence of informational stress among medical oncologists. We illustrate this hypothesis regarding adjuvant treatment of breast cancer. Specific studies (qualitative and quantitative ones) would be particularly interesting in oncology.
2
222-227
111
hyperconnexion; informational stress; medical decision-making; prise de décision médicale; stress informationnel
09
Février
S0007-4551(23)00444-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
Femelle
prise de décision
tumeurs du sein
oncologie médicale

---
Une chambre des erreurs comme moyen d’apprentissage dans une faculté de pharmacie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38204507
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754409
Ayed A
Zribi K
10.4212/cjhp.3436
1
e3436
77
danger; educational workshop; medicine; safety
cjhp-77-1-3436
publication électronique
Accès restreint
résumé en anglais
article de périodique

---
: Le modèle de la publication continue.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38204509
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754411
Shalansky S
10.4212/cjhp.3571
1
e3571
77
cjhp-77-1-3571
publication électronique
Accès restreint
éditorial

---
Pronostic obstétrical et néonatal des patientes ayant un antécédent de mutilation génitale féminine.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38211770
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00006-0
Selides S
Nallet C
Vouga M
Mottet N
Ramanah R
10.1016/j.gofs.2024.01.002
AbstractText Label OBJECTIVE Female genital mutilation (FGM) covers all procedures involving partial or total removal of the external genitalia for non-therapeutic purposes. The period of pregnancy and childbirth is probably more at risk of complications for these women. The main aim of this study was to compare obstetrical, maternal and neonatal outcomes in patients with a history of female genital mutilation with patients without such a history. /AbstractText AbstractText Label METHODS All deliveries taking place between January 2005 and June 2022 at Besançon University Hospital in patients with a history of FGM were included. This group was compared with a randomly selected group of deliveries of patients with no history of FGM. A total of 87 deliveries with a history of FGM were included and compared with 696 deliveries with no history of FGM. /AbstractText AbstractText Label RESULTS There were significantly more instrumental deliveries (27.6% vs. 17.5%, p 0.01), more caesarean sections (23% vs. 14.1%, p 0.01), more episiotomies (9.2% vs. 0.7%, p 0.01), more first-degree perineal tears (30.8% vs. 20.8%, p 0.02), second-degree (13.9% vs. 5.3%, p 0, 01), third-degree (3.1% vs. 0.2%, p 0.02), more anterior perineal tears (23.1% vs. 2.5%, p 0.01), increased duration of pushing efforts (13 mins vs. 10 mins, p 0.05) and greater blood loss (297 cc vs. 165 cc, p 0.01) in the group with a history of FGM. There was no statistically significant difference in neonatal outcome. /AbstractText AbstractText Label CONCLUSION The obstetrical prognosis of patients with a history of FGM is significantly poorer. Neonatal prognosis remains unchanged. /AbstractText
excision; female genital mutilation; infibulation; prognosis
09
Janvier
S2468-7189(24)00006-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Une cause inhabituelle de masse palpébrale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38212205
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00570-3
Sarubbi C
Simonin M
Gauthier AS
Solecki L
10.1016/j.jfo.2023.104038
2
104038
47
10
Février
S0181-5512(23)00570-3
publication avant impression
Accès restreint
lettre
humains
tumeurs de la paupière
tumeurs de la paupière
paupières
blépharoptose

---
Caractéristiques et profils évolutifs des patients avec un diagnostic récent d’artérite à cellules géantes, étude NEWTON.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38216390
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(23)01322-X
Goncalves L
Tran VT
Chauffier J
Bourdin V
Nassarmadji K
Vanjak A
Bigot W
Burlacu R
Champion K
Lopes A
Depont A
Borrero BA
Mangin O
Adle-Biassette H
Bonnin P
Boutigny A
Bonnin S
Neumann L
Mouly S
Sène D
Comarmond C
10.1016/j.revmed.2023.12.005
AbstractText Label INTRODUCTION The management of giant cell arteritis (GCA) has evolved with the arrival of tocilizumab (TCZ) and the use of PET/CT. Our objective is to describe the characteristics and followup of patients with recent diagnosis of GCA in current care. /AbstractText AbstractText Label PATIENTS AND METHODS The NEWTON cohort is a monocentric retrospective cohort based on data collected from 60 GCA patients diagnosed between 2017 and 2022 according to the ACR/EULAR 2022 criteria. /AbstractText AbstractText Label RESULTS The median age at diagnosis was 73 [68.75; 81] years old. At diagnosis, the main manifestations were unusual temporal headaches in 48 (80 %) and an inflammatory syndrome in 50 (83 %) patients. Temporal artery biopsy confirmed the diagnosis in 49/58 (84 %) patients. Doppler of the temporal arteries found a halo in 12/23 (52 %) patients. The PET/CT found hypermetabolism in 19/43 (44 %) patients. Prednisone was stopped in 17.5 [12.75; 24.25] months. During follow-up, 22 (37 %) patients received TCZ. At least one complication of corticosteroid therapy was observed in 22 (37 %) patients. After a median follow-up of 24 [12; 42] months, 25 (42 %) patients relapsed. At the end of the follow-up, 29 (48.3 %) patients were weaned from corticosteroid therapy and 15 (25 %) were on TCZ. /AbstractText AbstractText Label CONCLUSION Despite the increasing use of TCZ in the therapeutic arsenal and of the PET/CT in the imaging tools of GCA patients, relapses and complications of corticosteroid therapy remain frequent, observed in more than a third of patients. /AbstractText
artérite à cellules géantes; giant cell arteritis; large vessel; pet scanner; positron emisson tomography; rechute; relapse; tocilizumab; vascularite des gros vaisseaux
11
Janvier
S0248-8663(23)01322-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Une rétinopathie peut en cacher une autre.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38216406
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00578-8
Timoumi R
Giocanti-Aurégan A
Fajnkuchen F
Torres-Villaros H
10.1016/j.jfo.2023.104046
3
104046
47
11
Mars
S0181-5512(23)00578-8
publication avant impression
Accès restreint
lettre
humains
nouveau-né
rétinopathie du prématuré

---
1. Adénome vésiculaire d’architecture papillaire.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38216435
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(23)00235-3
Guyétant S
10.1016/j.annpat.2023.12.007
2
96-100
44
11
Mars
S0242-6498(23)00235-3
publication avant impression
Accès restreint
article de périodique
humains
tumeurs de la thyroïde
adénocarcinome folliculaire

---
Localisation hépatique isolée d’une histiocytose langerhansienne : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38216436
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(23)00229-8
Allaume P
Meneyrol E
Bernard G
Houssel-Debry P
Emile JF
Turlin B
10.1016/j.annpat.2023.12.001
Langerhans cell histiocytosis (LCH) is a disease whose physiopathology remains unclear, involving both inflammatory processes and clonal proliferation. It is observable at any given age, although about ten times more frequent in children than adults. Hepatic involvement is not rare, mostly part of a systemic disease, and linked to a poor prognosis. We report here a case of LCH with solitary hepatic involvement in a 74 year-old patient. This case demonstrated molecular anomaly of the MAPK pathway, BRAF N486_P490del. Through this observation, we precise the epidemiological and histological aspects and diagnostic criteria of this rare disease.
1
69-74
44
cholangite; cholangitis; foie; histiocytose; histiocytosis; langerhans; liver; mapk
11
Février
S0242-6498(23)00229-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
adulte
enfant
humains
sujet âgé
histiocytose à cellules de langerhans
maladies rares
foie

---
trimestre de la grossesse en population à bas risque?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218336
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00005-9
Quarello E
10.1016/j.gofs.2024.01.001
11
Janvier
S2468-7189(24)00005-9
publication avant impression
Accès restreint
éditorial

---
Agents antibactériens et lutte contre la résistance aux antibiotiques: analyse de la consommation et des dépenses d'une entreprise italienne de soins de santé dans le monde réel.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218426
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00001-4
Ferrara F
Capuozzo M
Pasquinucci R
Langella R
Trama U
Nava E
Zovi A
10.1016/j.pharma.2024.01.001
antibiotic resistance; antibiotics; appropriateness; assessment; consumption; defined daily dose
11
Janvier
S0003-4509(24)00001-4
publication avant impression
Accès restreint
article de périodique

---
L'insuffisance rénale chronique en Amérique, en Afrique et en Asie: aperçu des coûts et des options de traitement.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218427
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00002-6
Mourchid R
Yassine A
Bellahcen M
Cherrah Y
Serragui S
10.1016/j.pharma.2024.01.002
Chronic kidney disease (CKD) is one of the non-infectious diseases that threaten patients' lives on a daily basis. Its prevalence is high, but under-reported by patients and those living with the disease, as it is silent and asymptomatic in the early stages. Kidney disease increases the risk of heart and vascular disease. These problems can manifest themselves slowly, over a long period of time. Early detection and treatment can often prevent chronic kidney disease from worsening. As kidney disease progresses, it can lead to kidney failure, requiring dialysis or a kidney transplant to stay alive. in this narrative review we will mainly discuss different treatment option costs in different countries and how much they cost healthcare systems in countries in three different continents.
chronic kidney disease (ckd); cost; coût; dialyse; dialyse péritonéale; dialysis; hemodialysis; hémodialyse; maladie rénale chronique (mrc); options de traitement; peritoneal dialysis; treatment options
11
Janvier
S0003-4509(24)00002-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

---
La littératie en santé, quels enjeux en santé mentale ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218614
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00195-0
Liné C
10.1016/j.spsy.2023.11.001
350
1
45
S0241-6972(23)00195-0
publication papier
Accès restreint
éditorial
humains
compétence informationnelle en santé
santé mentale

---
Quelle place pour l’éthique en psychiatrie ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218615
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00197-4
Arcas PM
10.1016/j.spsy.2023.11.003
At a time when healthcare establishments are facing sensitive financial and institutional challenges, how can ethics be given a place in psychiatry? In society, ethical debates focus on surrogate motherhood, active euthanasia or assisted suicide, and embryo research. In psychiatry, the question often crystallizes around violent incidents that are hardly representative of the daily lives of professionals and patients. Militant discourse prevails over listening to the people concerned. The law requires establishments to reflect on the ethical issues raised by the reception and medical care of patients, without specifying the boundaries. Ethics in healthcare facilities focuses on care situations - what is possible or desirable - with no single theoretical model to serve as an example to follow.
350
10-13
45
autonomie; autonomy; collegiality; collégialité; discussion; ethical reflection; multidisciplinarity; pluridisciplinarité; réflexion éthique
S0241-6972(23)00197-4
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
psychiatrie
prestations des soins de santé

---
Psy le comité nous était conté.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218616
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00199-8
d'éthique C
10.1016/j.spsy.2023.11.004
Speaking on behalf of others is no easy task. When 30 members of a psychiatric hospital's ethics committee rely on three of them to explain its functions and roles to neophytes, and to put into words what the committee represents in their eyes, the mission is a delicate one. We have to remain as faithful to our own thinking as we are to the spirit of the group. We will try to answer these questions as best we can, to shed light on the origins, missions and specific features of an ethics committee in a psychiatric hospital, without betraying our own thinking or that of our colleagues.
350
14-16
45
collectif; collective; comité; committee; exchange; moral; morale; reflection; réflexion; valeur; value; échange
S0241-6972(23)00199-8
publication papier
Accès restreint
résumé en anglais
article de périodique
propargite
cyclohexanes
humains
hôpitaux psychiatriques
comités d'éthique clinique

---
Du soin psychiatrique au soin psychique, pour une éthique de la retenue.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218617
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00200-1
Hazif-Thomas C
10.1016/j.spsy.2023.11.005
This analysis of the ethical issues raised by the relationship between caregiver and patient is based on the history of psychiatry and sensitivity to the ethical tensions that run through the field of psychiatry and mental health. Taking a step back from the injunction to treat well, not fetishizing it, adopting a holistic approach, equipping ourselves to counter the stigmatization and self-stigmatization that so often accompany psychic and/or psychosocial disability, and inviting reflection on proportionality in mental health are all ethical priorities that are insufficiently invested in psychiatric clinics.
350
17-21
45
care; droit; empathie; empathy; ethics; law; mental health; proportionality; proportionnalité; santé mentale; soin; éthique
S0241-6972(23)00200-1
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
troubles mentaux
psychiatrie
psychothérapie
santé mentale

---
Autonomie revendiquée et aide médicale à mourir, la place de la psychiatrie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218618
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00201-3
Chastang F
10.1016/j.spsy.2023.11.006
Autonomy has become the highest value in our society, and while it is having an impact on the debate on a future law on medical assistance in dying, it is also opening the door to a reflection on vulnerability. Although seemingly unaffected, at least initially, psychiatry could join the field of this reflection and bring out the avenues of renewal.
350
22-25
45
autonomie; autonomy; ethics; mental suffering; physician-assisted suicide; psychiatric disorder; souffrance psychique; suicide médicalement assisté; trouble psychiatrique; éthique
S0241-6972(23)00201-3
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
suicide assisté
autonomie personnelle
psychiatrie
prévision

---
Au cœur du management du soin, la relation.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218619
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00202-5
Monteil PO
10.1016/j.spsy.2023.11.007
The prevalence of management concerns in hospitals and a highly normative conception of health care are converging today in a standardization of care. The latter is undoubtedly at the root of the current malaise among caregivers. Indeed, the New Public Management approach is encouraging them, despite themselves, to carry out their missions to the detriment of the values of care. A more appropriate form of management would, on the contrary, be based on a continuity to be sought between care values and management values, around the notion of support. This would mean reinstating concern for interpersonal relationships at the heart of care management missions.
350
26-28
45
authority; autorité; care; cooperation; coopération; gestion; hospital; hôpital; management; soin
S0241-6972(23)00202-5
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
hôpitaux
prestations des soins de santé

---
Réflexions éthiques autour des enfants vivant auprès de leurs mères incarcérées.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218620
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00203-7
Ogrizek A
Radjack R
Moro MR
10.1016/j.spsy.2023.11.008
In France, pregnant women or women with children under the age of 18 months, and in exceptional cases 24 months, can serve their prison sentences in specially equipped nurseries or mother-child cells. This situation is likely to have a negative impact on the child's health, and on the quality of the bond with the mother over the longer or shorter term. The benefits of maintaining this bond are indisputable, whatever the setting. Improvements to this system could be considered and implemented.
350
29-32
45
cellule mère-enfant; ethics; lien mère-enfant; mother-child bond; mother-child unit; nurserie carcérale; prison nursery; psychological health; santé psychique; éthique
S0241-6972(23)00203-7
publication papier
Accès restreint
résumé en anglais
article de périodique
grossesse
Femelle
humains
nourrisson
mères
France

---
Envisager la question de l’isolement et de la contention en psychiatrie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218621
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00204-9
Picquet G
10.1016/j.spsy.2023.11.009
In an ever-changing environment, the question of the meaning of care within a caring, ethical framework is of paramount importance. The development of a patient-centred approach relies on an understanding of the Other. Caring and empathy are the essential foundations of this approach. An attempt to analyze practices through a few notions of ethics can be proposed.
350
33-37
45
care; commodification; dignity; dignité; empathie; empathy; responsabilité; responsibility; réification; vulnerability; vulnérabilité
S0241-6972(23)00204-9
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
troubles mentaux
isolement du patient
psychiatrie
contention physique
patients
empathie

---
La santé mentale, une question écosystémique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218622
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00205-0
Lambrette G
10.1016/j.spsy.2023.11.010
The question of mental health can be approached using the three-dimensional model. In the light of the biological, environmental and circumstantial ingredients characterizing it, a critical analysis of both diagnosis and treatment can be proposed. The environment, like the individual, is both a factor and a player in psychological suffering. Treating one as well as the other is therefore the challenge of an ecosystemic approach.
350
40-42
45
diagnosis; diagnostic; ecosystem; mental health; modèle tridimensionnel; santé mentale; three-dimensional model; traitement; treatment; écosystème
S0241-6972(23)00205-0
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
santé mentale
écosystème
troubles mentaux
anxiété

---
Une enquête auprès des IPA parcours psychiatrie et santé mentale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218623
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00206-2
Gakou S
Vlasie M
10.1016/j.spsy.2023.11.011
A survey was conducted in June 2022 among the graduate RPNs in the field of psychiatry and mental health. 48 people responded and gave their views on their implementation and job satisfaction. The results were generally positive.
350
44-47
45
advanced practice nurse; enquête; implantation; implementation; infirmier en pratique avancée; psychiatrie et santé mentale; psychiatry and mental health; satisfaction; survey
S0241-6972(23)00206-2
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
santé mentale
pratique infirmière avancée
psychiatrie

---
Éthique et psychiatrie, de la manière de vivre à la manière de prendre soin.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38218624
https://linkinghub.elsevier.com/retrieve/pii/S0241-6972(23)00196-2
Peroche C
10.1016/j.spsy.2023.11.002
350
9-38
45
S0241-6972(23)00196-2
publication papier
Accès restreint
éditorial
humains
psychiatrie

---
Évolution du taux d’épisiotomies et des lésions obstétricales du sphincter de l’anus depuis les recommandations de 2018.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38219814
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00007-2
Leclercq C
Braund S
Verspyck E
10.1016/j.gofs.2024.01.003
AbstractText Label OBJECTIVES There is a progressive reduction in the rate of episiotomies since the recommendations of the french college of gynaecologists. Our objective was to study the evolution of the rate of episiotomies and Obstetric Anus Sphincter Injury (OASI) since the restriction of episiotomies in our department. /AbstractText AbstractText Label METHODS Observational monocentric retrospective study performed at the Rouen University Hospital. The inclusion criteria were monofetal pregnancies, delivery at a term greater than or equal to 37 weeks of amenorrhea of a living, viable child and by cephalic presentation. We compared two periods corresponding to before and after the 2018 recommendations. We used logistic regression modelling to identify factors associated with the risk of episiotomies and of obstetrical anal injuries, overall and in case of instrumental delivery. /AbstractText AbstractText Label RESULTS We included 3329 patients for the 1st period and 3492 for the 2nd period, and the rate of instrumental deliveries were respectively of 16,4 % (n 547) and 17,9% (n 626). Multivariate analysis showed a significant decrease in the rate of episiotomies in the 2nd period (OR 0,14, IC 95% [0,12 ; 0,16], p 0,0001). Main factors associated with the risk of OASI were primiparity (OR 6,21, IC 95% [3,19 ; 12,11]) and the use of forceps (OR 4,23, IC 95% [2,17 ; 8,27]) overall; and instrumental delivery using forceps (OR 3,25, IC 95% [1,69 ; 6,22]) and delivery during the 2nd period (OR 1,98, IC 95% [1,01 ; 3,88]) in case of instrumental delivery. /AbstractText AbstractText Label CONCLUSIONS Our study confirms that the voluntary reduction in the episiotomy rate does not seem to be associated with an increased risk of OASI, overall and in case of instrumental delivery. However, we show an increase in the rate of OASI in case of instrumental delivery since the latest recommendations. /AbstractText
2
95-101
52
oasi; episiotomy; instrumental delivery; severe perineal tear; vaginal delivery
12
Février
S2468-7189(24)00007-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
étude d'observation
Femelle
enfant
grossesse
humains
épisiotomie
canal anal
études rétrospectives
facteurs de risque
accouchement (procédure)
Complications du travail obstétrical
nouveau-né

---
La sénologie à l’ère de la désescalade et de la personnalisation des soins.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38219815
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00010-2
Mathelin C
10.1016/j.gofs.2024.01.006
3
123-124
52
breast cancer; cancer du sein; activité physique; chirurgie; chirurgie axillaire ciblée; lymphoedema; lymphœdème; physical activity; surgery; target axillary dissection
12
Mars
S2468-7189(24)00010-2
publication avant impression
Accès restreint
éditorial

---
Nouveautés dans la prise en charge de l’hyperkaliémie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38220492
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00004-3
Lefevre F
Mousseaux C
Bobot M
10.1016/j.revmed.2024.01.004
Hyperkalemia is common in everyday clinical practice, and is a major risk factor for mortality. It mainly affects patients with chronic renal failure (CKD), diabetes or receiving treatment with inhibitors of the renin-angiotensin-aldosterone system (iRAAS). Therapeutic management aims not only to avoid the complications of hyperkalemia, but also to avoid discontinuation of cardio- and nephroprotective treatments such as iRAAS. The use of polystyrene sulfonate, widely prescribed, is often limited by patient acceptability. Recent data have cast doubt on its safety, particularly in terms of digestive tolerance. Two new potassium exchange molecules have appeared on the market: patiromer and zirconium sulfonate. Their value in clinical practice, and their acceptability in the event of prolonged prescription, remain to be demonstrated. The combination of a thiazide diuretic or an inhibitor of the sodium-glucose cotransporter type 2 (iSGLT2) with iRAAS therapy in CKD, may also improve control of kalemia. At present, there are no recommendations for the positioning of the various hypokalemic treatments. The choice of these treatments must be adapted to the patient's pathologies and consider the other expected effects of these molecules.
hyperkalemia; hyperkaliémie; patiromer; polystyrene sulfonate; polystyrène sulfonate; potassium; sodium zirconium cyclosilicate; therapeutics; thérapeutique
13
Janvier
S0248-8663(24)00004-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
A propos de 39 cas de diverticules sous-urétraux de la femme: expérience monocentrique sur 30 ans.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38223879
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10787138
https://www.panafrican-med-journal.com/content/article/46/51/full/
Lachkar S
Ibrahimi A
Boualaoui I
El Sayegh H
Nouini Y
10.11604/pamj.2023.46.51.41246
We here report a retrospective analysis of 30 years experience with 39 female patients suffering from suburethral diverticula. The average age of patients was 37 years of age (24-56 years). The average parity was 2 (1-7); 65% of deliveries were complicated by dystocia, with forceps used in 43% of cases. All patients had a history of urological or gynaecological infections. The revealing symptoms were heterogeneous but recurrent urinary tract infections (26 cases), pollakiuria (23 cases), post-micturition urethral discharge (21 cases), vaginal pain (17 cases) and a sensation of vaginal bulge (15 cases) were mostly reported. Radiological assessment were performed, including intravenous urography, retrograde and micturition urethrography, ultrasound, or MRI. Transvaginal diverticulectomy was the treatment of choice for all patients, with no reported intraoperative complications. At 4 years of follow up outcome was satisfactory. Four patients developed recurrence of diverticulitis. These data provide important information about clinical features, diagnostic results and long-term outcomes of transvaginal diverticulectomy, enabling better management of this rare condition.
51
46
suburethral diverticulum; recurrent urinary tract infections; transvaginal diverticulectomy
PAMJ-46-51
publication électronique
Accès restreint
présentations de cas
résumé en anglais
Femelle
humains
adulte
jeune adulte
adulte d'âge moyen
maladies de l'urètre
maladies de l'urètre
maladies de l'urètre
études rétrospectives
radiographie
infections urinaires
diverticule
diverticule

---
Cartographier les activités de recherche en responsabilité sociale en santé d’une communauté internationale en émergence.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38226299
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10787869
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38226299/
Dubé T
Beaulieu MD
Fourati M
Benaskeur I
10.36834/cmej.76320
6
114-117
14
Décembre
CMEJ-14-114
publication électronique
Accès restreint
résumé en anglais
article de périodique
responsabilité sociale
recherche

---
Le coaching narratif collaboratif en médecine : une étude de cas avec une médecin résidente et une médecin en pratique à l’urgence.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38226307
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10787870
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38226307/
Truong S
Rodrigue F
Culver D
10.36834/cmej.75601
In recent years, many postgraduate medical institutions are transitioning to a competency based medical education (CBME). This paradigm shift offers many advantages but has also been criticized for its potentially reductionist approach of targeting competency as the end goal. In this context, coaching may be an interesting intervention as it has been employed with success in other professional settings to go beyond achieving competency with a focus on continuous development. Currently there is little published data on this intervention in the medical field. Our study aims to describe a coaching intervention between two dyads of a coach and physician as well as exploring the repercussions of the intervention on their professional practice by analyzing interviews conducted per the value creation framework. Results of our study show the unique learning journeys of both dyads as well as the creation of value in each cycle for both participants. In conclusion, coaching in medicine is an interesting intervention with the potential to complement the existing medical training programs in order to achieve optimal professional development.Au courant des dernières années, plusieurs programmes de résidence ont modifié leur structure vers une approche basée sur les compétences. Ce changement de paradigme a plusieurs avantages, mais l’approche axée sur les compétences est aussi critiquée pour son caractère potentiellement réductionniste en ciblant seulement les compétences. Afin de pallier à cette fin, le coaching est une intervention employée dans divers champs professionnels avec succès parce qu’il permet d’aller au-delà de la compétence en ciblant plutôt le développement des professionnels. Toutefois, peu de données existent sur ce type d’intervention dans le domaine médical. Le but de notre étude est d’explorer la co-création de valeur du coaching chez deux médecins. Cette étude de cas décrit le processus d’accompagnement de deux dyades coach-médecin en plus d’explorer les répercussions générées par cette intervention sur la pratique professionnelle des participantes à l’aide de l’analyse d’entrevues selon le cadre de création de valeurs. Les résultats démontrent que l’approche permet l’émergence de deux parcours d’apprentissages uniques en plus de créer de la valeur pour chacune des apprenantes. En conclusion, le coaching en médecine est un outil pédagogique intéressant qui bonifie la structure médicale actuelle afin de contribuer au développement professionnel des médecins.
6
51-65
14
Décembre
CMEJ-14-051
publication électronique
Accès restreint
résumé en anglais
article de périodique
humains
modèle de compétence attendue
médecine
enseignement médical
médecins

---
François Gros : Une personnalité de premier plan, un homme secret.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38226441
https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.142
https://doi.org/10.5802/crbiol.142
Robert B
10.5802/crbiol.142
I joined François Gros' laboratory in 1975, to study mechanisms of gene expression in eukaryotes. Despite the lack of powerful tools, that would be brought later by genetic engineering, I obtained publishable results and was allowed to defend a third cycle thesis. Thereafter, I joined Margaret Buckingham's group, which was empowering within François' laboratory. I maintained regular meetings with François, a leading figure but a secretive man, who did not readily open up. It was my privilege, over the more than 45 years I have been around him, to have glimpses over what had been really significant to him. This has been a rich and very precious experience.cycle. Après cela, j’ai rejoint le groupe de Margaret Buckingham, qui s’autonomisait dans le laboratoire de François. J’ai continué à avoir des rencontres régulières avec François, personnalité de premier plan mais homme secret, qui ne se livrait pas volontiers. J’ai eu le privilège, au cours des 45 ans et plus où je l’ai côtoyé, d’avoir quelques aperçus de ce qui l’avait marqué, l’avait formé, lui importait vraiment. Ça été une expérience riche et très précieuse.
S2
41-43
346
françois gros; homme secret; personnalité de premier plan; premières expériences de recherche
29
Mars
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
Mâle
Récit personnel
article historique

---
Les plans d’action écrits pour l’asthme : quel usage en font les pneumologues en France ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38228440
http://www.em-consulte.com/retrieve/pii/S0761-8425(24)00001-9
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00001-9
Soumagne T
Chenivesse C
Didier A
Giovannini-Chami L
Magnan A
Taillé C
et les investigateurs du groupe d’étude PAE
10.1016/j.rmr.2024.01.001
AbstractText Label INTRODUCTION Despite evidence of the benefits of the written asthma action plans (WAP) in asthma control, they remain poorly applied. The aim of our study was to assess the practices of French-speaking pulmonologists and paediatricians in their use of WAP for asthma control and to analyse the contents of several WAPs routinely consulted in treatment of asthma patients. /AbstractText AbstractText Label METHODS Members of three French medical societies (SPLF, G2A, SP2A) were requested to share their WAPs for asthma patients and to participate in an online survey about the possible influence of these documents on their practices. /AbstractText AbstractText Label RESULTS Most (95%) of the 41 WAPs taken into consideration were symptom-based and 34% included peak expiratory flow measurement. All of these action plans were in full compliance with current guidelines. Among the 110 survey respondents, while 65% systematically provided a WAP to their asthma patients, only 30% often or always supplemented the written document with therapeutic education sessions. In almost every case, it was the doctor who presented the WAP to the patient, generally devoting to less than 10minutes to explanation of what they were handing out. /AbstractText AbstractText Label CONCLUSIONS In France, WAPs are generally presented to the patient by the physician, which probably limits the time devoted to explanation of their contents. Furthermore, WAPs are rarely reinforced with therapeutic education. The current study suggests ways of improving the utilization of WAPs in asthma care and treatment. /AbstractText
2
102-109
41
action plan; asthma; asthme; education; plan d’action; éducation
15
Février
S0761-8425(24)00001-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
asthme
asthme
Observance par le patient
autosoins
France

---
À propos d’une e-Hypercalcémie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38228453
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00003-1
Guillaud P
Vest P
Billhot M
Doutrelon C
Hejl C
10.1016/j.revmed.2024.01.002
AbstractText Label INTRODUCTION Hypercalcemia is a common biological abnormality. The etiologies are mainly represented by hyperparathyroidism and neoplastic causes. The other causes, including poisoning, are rare, but should not be neglected. /AbstractText AbstractText Label OBSERVATION An 82-year-old female patient presented to the emergency room for repeated falls at home, confusion, drowsiness and digestive symptoms. The initial assessment showed hypercalcemia above 3mmol/L. The etiological exploration revealed a very high concentration of 25OH-vitamin D. After repeated interrogations, it appeared that the cause of this intoxication was the intake of a food supplement purchased on the internet, following a prescription from her dentist. /AbstractText AbstractText Label CONCLUSION Intoxication due to a food supplement containing vitamin D is possible and potentially serious. Raising the awareness of patients and healthcare professionals is necessary in order to prevent this type of poisoning and/or to diagnose it as soon as possible. /AbstractText
3
142-146
45
auto-médication; complément alimentaire; dietary supplements; hypercalcemia; hypercalcémie; hypervitaminose d; hypervitaminosis d; self-medication
15
Mars
S0248-8663(24)00003-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
vitamine D
vitamines
Femelle
humains
sujet âgé de 80 ans ou plus
hypercalcémie
hypercalcémie
compléments alimentaires

---
, mais sans diabète, est-ce que le sémaglutide diminue le risque de mortalité cardiovasculaire, d’infarctus du myocarde ou d’AVC comparativement au placebo tout en étant sécuritaire ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38228454
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00007-9
Lanthier L
Langlois MF
Plourde MÉ
Cauchon M
10.1016/j.revmed.2024.01.006
3
178-179
45
15
Mars
S0248-8663(24)00007-9
publication avant impression
Accès restreint
lettre
sémaglutide
hypoglycémiants
peptides glucagon-like
adulte
humains
maladies cardiovasculaires
indice de masse corporelle
infarctus du myocarde
infarctus du myocarde
accident vasculaire cérébral
diabète de type 2
diabète de type 2
hypoglycémiants

---
Face au désenchantement des étudiants en médecine, les facultés sont prêtes à innover.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231091
https://doi.org/10.53738/REVMED.2024.20.856-7.05
Geissbühler A
Pascual M
10.53738/REVMED.2024.20.856-7.05
856-7
5-8
20
17
Janvier
RMS0856-7-001
publication papier
Accès restreint
entretien
humains
étudiant médecine

---
Addictions: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231092
https://doi.org/10.53738/REVMED.2024.20.856-7.12
Zullino D
Vogel M
Meyer M
Simon O
Bisson M
Corino T
Penzenstadler L
10.53738/REVMED.2024.20.856-7.12
Addiction medicine is currently facing new challenges, such as drug epidemics and open drug scenes. It is responding to these challenges with a range of innovations: 1. The commercialization of opioid-assisted treatment (OAT) is a major step forward. 2. In Geneva, a community outreach project involving mental health peer practitioners targets the emerging crack scene, demonstrating its effectiveness in directing this marginalized population towards care. 3. In Switzerland, two projects in French-speaking Switzerland are testing hybrid models of cannabis regulation. Evaluation of these projects will guide the best approach to cannabis regulation.L’addictologie est actuellement confrontée à des nouveaux défis, tels que des épidémies de consommation et des scènes de drogues ouvertes. Elle répond à ces défis par différentes innovations. 1. La commercialisation du traitement assisté par opioïdes (TAO) en dépôt est une avancée majeure. 2. À Genève, un projet communautaire de maraudes, impliquant des pairs praticiens en santé mentale, cible la scène de consommation de crack émergente, montrant son efficacité pour orienter cette population marginalisée vers les soins. 3. En Suisse, deux projets romands testent des modèles hybrides de régulation du cannabis. L’évaluation de ces projets guidera la meilleure approche pour la régulation du cannabis.
856-7
12-14
20
17
Janvier
RMS0856-7-002
publication papier
Accès restreint
résumé en anglais
article de périodique
analgésiques morphiniques
hallucinogènes
humains
Comportement toxicomaniaque
cannabis
épidémies

---
Angiologie et hémostase: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231093
https://doi.org/10.53738/REVMED.2024.20.856-7.15
Casini A
Robert-Ebadi H
Glauser F
Blondon M
Fontana P
Righini M
10.53738/REVMED.2024.20.856-7.15
We discuss four topics among the angiology and hemostasis studies of importance in 2023. The BASIL-2 study provides new data for the management of chronic limb-threatening ischemia by comparing surgical and endovascular treatment. The new classification of antiphospholipid antibody (aPL) syndrome integrates new clinical elements and gives a different weight among the isotype and titer of aPL. Concizumab, an antibody targeting the tissue factor pathway inhibitor, broadens the therapeutic arsenal for hemophilia A and B as evidenced by the results of the EXPLORER 7 study. The PREVENT-CLOT and CASTING study focus on the prevention of thrombosis after trauma, by testing the role of aspirin or the lack of thromboprophylaxis, respectively.Parmi les sujets d’angiologie et d’hémostase qui ont marqué l’année 2023, quatre ont retenu notre attention. L’étude BASIL-2 apporte de nouvelles données pour la prise en charge de l’ischémie critique des membres inférieurs en comparant les traitements chirurgical et endovasculaire. La nouvelle classification du syndrome des anticorps antiphospholipides (aPL) intègre de nouveaux items cliniques et donne un poids différent aux isotypes et titres des aPL. Le concizumab, un anticorps ciblant l’inhibiteur de la voie du facteur tissulaire, vient élargir l’arsenal thérapeutique pour les hémophilies A et B comme en témoignent les résultats de l’étude EXPLORER 7. Les études PREVENT-CLOT et CASTING s’intéressent à la prévention de la thrombose après traumatisme, en testant la place de l’aspirine ou l’absence de thromboprophylaxie.
856-7
15-18
20
17
Janvier
RMS0856-7-003
publication papier
Accès restreint
résumé en anglais
article de périodique
anticoagulants
humains
thromboembolisme veineux
hémophilie A
cardiologie
hémostase

---
Cardiologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231094
https://doi.org/10.53738/REVMED.2024.20.856-7.19
Salihu A
Meier D
Kilani N
Burdet O
Tzimas G
Antiochos P
Masi A
Teres C
Ascione C
Rosset S
Daux A
Domenichini G
Ladouceur M
Yerly P
Schwitter J
Monney P
Rutz T
Bouchardy J
Pruvot E
Muller O
Fournier S
10.53738/REVMED.2024.20.856-7.19
The year 2023 has been extremely rich in new publications in the various subfields of cardiology. Furthermore, the European Society of Cardiology (ESC) has issued revised guidelines focused on the management of acute coronary syndrome (ACS) and endocarditis, as well as an update on the recommendations for the management of heart failure and cardiovascular prevention. The most significant updates according to the Cardiology Department of CHUV are summarized in this review article.L’année 2023 a été extrêmement riche en nouvelles publications dans les différents sous-domaines de la cardiologie. De plus, la Société européenne de cardiologie (ESC) a formulé des directives révisées axées sur le management du syndrome coronarien aigu (SCA) et de l’endocardite ainsi qu’une mise à jour des recommandations sur la prise en charge de l’insuffisance cardiaque et la prévention cardiovasculaire. Les nouveautés les plus importantes selon l’équipe du Service de cardiologie du CHUV sont résumées dans cet article de synthèse.
856-7
19-24
20
17
Janvier
RMS0856-7-004
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
cardiologie
défaillance cardiaque
défaillance cardiaque
syndrome coronarien aigu
syndrome coronarien aigu
endocardite

---
Chirurgie viscérale: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231095
https://doi.org/10.53738/REVMED.2024.20.856-7.25
Sleiman MJ
Jelip A
Douissard J
Koessler T
Jung MK
Toso C
10.53738/REVMED.2024.20.856-7.25
In 2023, robotic surgery has witnessed an expansion in the number of surgical procedures and in the number of platforms on the market. We illustrate the phenomenon, by exploring parietal, œso-gastric and liver robotic surgery. Surgical innovation aligns with advancements in oncology. Immunotherapy now enables watch and wait strategies for patients with colorectal cancer, and decreases recurrence rate and improves survival after liver surgery for hepatocellular carcinoma and œso-gastric surgery. The multidisciplinary field of obesity management has seen the development of new medications, diversifying the treatment options, while surgery continues to deliver the best weight-loss outcomes.En 2023, la chirurgie robotique a poursuivi son expansion avec une augmentation du nombre d’interventions et la mise sur le marché de nouvelles plateformes. Ce phénomène est illustré dans cet article par la description des chirurgies robotique pariétale, œsogastrique et hépatique. L’innovation en chirurgie accompagne aussi celle de l’oncologie. L’immunothérapie permet maintenant une stratégie « watch and wait » chez les patients avec un cancer colorectal, diminue le risque de récidive et améliore la survie après chirurgie hépatique pour un carcinome hépatocellulaire et chirurgie œsogastrique. Le domaine multidisciplinaire de la prise en charge de l’obésité a aussi vu l’arrivée de nouveaux traitements médicamenteux, qui viennent diversifier les options thérapeutiques, où la chirurgie continue d’apporter les meilleurs résultats en termes de perte de poids.
856-7
25-31
20
17
Janvier
RMS0856-7-005
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
Interventions chirurgicales robotisées
carcinome hépatocellulaire
immunothérapie
tumeurs du foie

---
Diabétologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231096
https://doi.org/10.53738/REVMED.2024.20.856-7.32
Gariani K
Jornayvaz FR
10.53738/REVMED.2024.20.856-7.32
Diabetology is a continuously evolving discipline, many molecules are developed and treatment recommendations change often according to the latest published studies. It is therefore often difficult for the primary care physician to be up to date. After lifestyle measures that must always be preferred before any drug, metformin remains the pharmacological basis of treatment. Current recommendations favor the introduction of an SGLT2 inhibitor or a GLP-1 receptor agonist after metformin because these molecules have shown beneficial cardiovascular and renal effects. The purpose of this article is to guide the primary care physician to choose the most suitable pharmacological treatment for each patient, in the light of the 2023 novelties in the field of diabetes.La diabétologie est une discipline en évolution continue, de nombreuses molécules sont développées et les recommandations de traitement changent fréquemment en fonction des dernières études publiées. Il est donc souvent difficile pour le médecin de premier recours d’être à jour. Après les mesures du style de vie qu’il faut toujours privilégier avant toute approche médicamenteuse, la metformine reste la base pharmacologique du traitement. Les recommandations actuelles préconisent d’instaurer un inhibiteur du SGLT2 ou un agoniste du récepteur du GLP-1 après la metformine car ces molécules ont montré des effets bénéfiques cardiovasculaires et rénaux. Le but de cet article est de fournir une aide au médecin de premier recours dans le choix du traitement pharmacologique le plus adapté à chaque patient, à la lumière des nouveautés 2023 dans le domaine du diabète.
856-7
32-34
20
17
Janvier
RMS0856-7-006
publication papier
Accès restreint
résumé en anglais
article de périodique
metformine
humains
rein
mode de vie

---
Endocrinologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231097
https://doi.org/10.53738/REVMED.2024.20.856-7.36
Ameti A
Chouchane K
Fontana E
Papadakis GE
10.53738/REVMED.2024.20.856-7.36
This overview provides a selection of studies published in 2023 with an impact on clinical practice. In reproductive endocrinology, important studies have addressed fertility preservation in men with Klinefelter's syndrome, the cardiovascular safety of testosterone replacement therapy, and a novel therapy, fezolinetant, for vasomotor symptoms of menopause. The updated European recommendations concerning adrenal incidentalomas will considerably modify current clinical practice. Based on a solid epidemiological work, the prevalence of pituitary adenomas has been confirmed to affect about 1 per 1000 individuals. Finally, a large British study allows to refine the benefit-risk profile of the three options available for the treatment of hyperthyroidism.Cet aperçu présente une sélection d’études publiées en 2023 ayant un impact sur la pratique clinique. En endocrinologie de reproduction, des études importantes ont abordé la préservation de la fertilité chez les hommes avec un syndrome de Klinefelter, la sécurité cardiovasculaire du traitement substitutif par testostérone et une nouvelle thérapie, fezolinetant, pour les symptômes vasomoteurs de la ménopause. La mise à jour des recommandations européennes concernant les incidentalomes surrénaliens va considérablement modifier la pratique clinique. Grâce à un travail épidémiologique solide, la prévalence des adénomes hypophysaires est confirmée à environ 1 cas pour 1000 individus. Enfin, une large étude britannique permet de raffiner le profil bénéfices-risques des trois options disponibles pour le traitement de l’hyperthyroïdie.
856-7
36-41
20
17
Janvier
RMS0856-7-007
publication papier
Accès restreint
résumé en anglais
article de périodique
Mâle
Femelle
humains
tumeurs de la surrénale
endocrinologie
hormonothérapie substitutive
préservation de la fertilité
ménopause
revue de la littérature

---
Gastroentérologie et hépatologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231098
https://doi.org/10.53738/REVMED.2024.20.856-7.42
Fraga M
Wakim El-Khoury J
Oumrani S
Godat S
Vionnet J
Schoepfer A
Vieira Barbosa J
10.53738/REVMED.2024.20.856-7.42
2023 has been marked by numerous advancements in the fields of hepatology, liver transplantation, gastroenterology, and interventional endoscopy. These developments hold the promise of changing our daily practice while enhancing the diagnosis and treatment of various hepatic and gastroenterological conditions. Additionally, the European Association for the Study of the Liver (EASL) has issued recommendations for the management of hepatitis delta, acute-on-chronic liver failure, liver diseases of pregnancy, and intrahepatic cholangiocarcinoma. Risankizumab was approved by Swiss Authorities for patients with Crohn's disease and dupilumab was approved for patients with eosinophilic esophagitis. The European Society of Gastrointestinal Endoscopy (ESGE) has revised its recommendations regarding Barrett's esophagus.2023 a été marquée par de nombreuses avancées dans le domaine de l’hépatologie, de la transplantation hépatique, de la gastroentérologie et de l’endoscopie interventionnelle. Ces développements promettent de changer notre pratique quotidienne dans le but d’améliorer le diagnostic et le traitement de nombreuses affections hépatiques et gastroentérologiques. En outre, la Société européenne d’hépatologie (EASL) a émis des recommandations pour la prise en charge de l’hépatite delta, de l’insuffisance hépatique aiguë sur chronique, des complications hépatiques de la grossesse et du cholangiocarcinome intrahépatique. Le risankizumab a été approuvé par Swissmedic pour le traitement de la maladie de Crohn et le dupilumab pour les patients avec œsophagite à éosinophiles. La Société européenne d’endoscopie a mis à jour ses recommandations concernant l’œsophage de Barrett.
856-7
42-46
20
17
Janvier
RMS0856-7-008
publication papier
Accès restreint
résumé en anglais
article de périodique
Femelle
grossesse
humains
gastroentérologie
Insuffisance hépatique aigüe sur chronique
tumeurs des canaux biliaires
conduits biliaires intrahépatiques

---
Immunologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231099
https://doi.org/10.53738/REVMED.2024.20.856-7.47
Ringwald M
Ribi C
10.53738/REVMED.2024.20.856-7.47
Systemic lupus erythematosus (SLE) is a complex autoimmune disease affecting various organs and characterized by profound immune disturbances. Monoclonal antibodies such as anifrolumab, targeting type I interferon, and belimumab, targeting a cytokine that activates B-cells and plasmocytes, have shown efficacy in SLE. Voclosporine, a novel calcineurin inhibitor, improves renal outcomes when combined with standard immunosuppression in lupus nephritis. Other approaches like obinutuzumab and CAR-T cells offer hope for refractory patients. These advances diversify SLE management, though their long-term efficacy remains to be established. It is crucial to emphasize basic measures in patients with SLE, including smoking cessation, sun protection, and early use of hydroxychloroquine.Le lupus érythémateux systémique (LES) est une maladie auto-immune complexe pouvant toucher tous les organes et marquée par des altérations profondes du système immunitaire. De nouvelles thérapies telles que l’anifrolumab, ciblant l’interféron de type I, et le bélimumab, bloquant une cytokine stimulant les cellules B et plasmocytes, ont montré leur efficacité. Un nouvel inhibiteur de la calcineurine, la voclosporine, s’avère utile en adjonction au traitement classique dans la néphrite lupique. D’autres approches comme l’obinutuzumab et les cellules CAR-T sont un espoir pour les cas réfractaires. Ces récentes avancées diversifient la prise en charge du LES mais leur utilité à long terme reste à établir. Rappelons l’importance de mesures de base: arrêt du tabac, protection solaire et utilisation de l’hydroxychloroquine dès le diagnostic.
856-7
47-50
20
17
Janvier
RMS0856-7-009
publication papier
Accès restreint
résumé en anglais
article de périodique
anticorps monoclonaux
cytokines
humains
lupus érythémateux disséminé
anticorps monoclonaux
maladies auto-immunes
lymphocytes B

---
Maladie d’Alzheimer: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231100
https://doi.org/10.53738/REVMED.2024.20.856-7.51
Donayre D
Graf C
Frisoni G
Lathuilière A
10.53738/REVMED.2024.20.856-7.51
The increasing prevalence of Alzheimer's disease in the general population presents a number of medical, economic and social challenges for the years to come. After 20 years of research with no new treatment option, a new class of drugs is set to be introduced in Europe. Anti-amyloid drugs, which are already available in the United-States, slow the disease progression by targeting the biological processes causing the disease, unlike the symptomatic treatments that are currently available. However, their precise indications and the monitoring of their adverse events are still to be defined. Several other drugs are in advanced stages of development, such as those targeting the tau protein or neuroinflammation, suggesting that the management of the disease will be quite different in the years to come.L’augmentation du nombre de personnes atteintes de la maladie d’Alzheimer présente des enjeux médicaux, économiques et sociaux pour les années à venir. Après 20 années de recherche sans nouveauté médicamenteuse, une nouvelle classe de molécules est sur le point d’arriver sur le marché en Europe. Les traitements antiamyloïde, déjà commercialisés aux États-Unis, ralentissent le déclin cognitif en ciblant le processus biologique qui en est à l’origine, contrairement aux traitements symptomatiques disponibles actuellement. Cependant, leurs indications précises et la gestion de leurs effets indésirables restent encore à définir. D’autres traitements sont dans des phases avancées d’élaboration, comme ceux ciblant la protéine tau ou l’inflammation, laissant envisager que la prise en charge de la maladie sera bien différente dans les années à venir.
856-7
51-54
20
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Janvier
RMS0856-7-010
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
maladie d'Alzheimer
maladie d'Alzheimer
maladie d'Alzheimer
évolution de la maladie
Europe

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Maladies infectieuses: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231101
https://doi.org/10.53738/REVMED.2024.20.856-7.55
D'Incau S
Voide C
Berthod D
Catho G
Bellini C
Bally F
Emonet S
10.53738/REVMED.2024.20.856-7.55
The year 2023 saw the publication of several studies in various areas of infectious diseases. The administration of corticosteroids decreased mortality in severe community-acquired pneumonia. Administration of doxycycline post-exposure prophylaxis reduced the risk of bacterial sexually transmitted infections at the risk of resistance selection. An herbal preparation decreased mortality in sepsis. A meta-analysis concludes that oseltamivir does not significantly reduce the risk of hospitalisation for influenza. Discontinuation of antibiotic prophylaxis during dental procedures in Sweden did not increase the incidence of viridans group Streptococcus endocarditis. Several studies have led to the introduction of RSV (Respiratory Syncytial Virus (RSV) vaccination. 2023 also saw the resurgence of invasive Group A Streptococcal infections, of which clinicians must be wary.L’année 2023 est marquée par la publication d’études touchant des domaines variés de l’infectiologie. La mortalité de pneumonies communautaires sévères est diminuée par l’administration de corticostéroïdes. Lors de rapport sexuel à risque, l’administration de doxycycline en prophylaxie postexpositionnelle diminue le risque d’infections sexuellement transmissibles bactériennes, cependant au risque de sélectionner des bactéries résistantes. Une préparation de plantes diminue la mortalité du sepsis. Une méta-analyse conclut que l’oseltamivir ne diminue pas significativement le risque d’hospitalisation lors de grippe. L’arrêt de la prophylaxie antibiotique lors d’intervention dentaire en Suède n’a pas augmenté l’incidence d’endocardite à streptocoques du groupe viridans. Plusieurs études ont mené à l’introduction de la vaccination VRS (virus respiratoire syncytial humain). 2023 a aussi vu la résurgence d’infections invasives à streptocoques du groupe A dont le clinicien doit se méfier.
856-7
55-58
20
17
Janvier
RMS0856-7-011
publication papier
Accès restreint
résumé en anglais
article de périodique
méta-analyse
doxycycline
humains
maladies transmissibles
sepsie
infections à streptocoques
grippe humaine

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Médecine de l’adolescence. Expliquer la douleur chronique fonctionnelle aux adolescents.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231102
https://doi.org/10.53738/REVMED.2024.20.856-7.59
Ambresin AE
Wosinski B
10.53738/REVMED.2024.20.856-7.59
There is a growing body of scientific understanding surrounding the topic of functional chronic pain. Numerous studies have highlighted a persistent low-grade inflammation within the fascial and central nervous systems, coupled with detrimental neuroplasticity involving substantial remodeling of pain pathways in the spinal cord and brain. These findings provide a more concrete basis for explaining functional chronic pain to adolescents, simplifying the establishment of trust and the justification of proposed treatments in the process.Il y a de plus en plus de compréhension scientifique autour du thème de la douleur chronique fonctionnelle. Plusieurs études mettent en évidence une inflammation de bas grade, persistante, au niveau des systèmes fascial et nerveux central, ainsi qu’une neuroplasticité délétère avec un remodelage majeur des voies douloureuses de la moëlle épinière et du cerveau. Tous ces éléments permettent une meilleure compréhension des mécanismes qui sous-tendent la douleur chronique fonctionnelle et donnent ainsi la possibilité de l’expliquer plus concrètement aux adolescents comme partie intégrante de la prise en charge. Créer le lien de confiance devient plus simple, de même que la justification des traitements proposés.
856-7
59-62
20
17
Janvier
RMS0856-7-012
publication papier
Accès restreint
résumé en anglais
article de périodique
adolescent
humains
douleur chronique
médecine de l'adolescent
système nerveux central
encéphale
confiance

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Médecine d’urgence: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231103
https://doi.org/10.53738/REVMED.2024.20.856-7.63
Cahen D
Gay M
Jogna F
Garcia E
Adler MA
Truong P
Desmettre T
Darioli V
Fehlmann CA
10.53738/REVMED.2024.20.856-7.63
Research in prehospital and in-hospital emergency medicine is essential to the development of this discipline. By calling certain practices into question (thrombolysis for minor strokes, use of coagulation factors for patients with severe polytrauma), providing access to new technologies (video-laryngoscopy, POCT troponins in pre-hospital care) or questioning new practices (double defibrillation, pulmonary US in pneumonia), research enables emergency physicians to adapt their day-to-day practice.La recherche en médecine d’urgence, tant sur le plan préhospitalier qu’hospitalier, est nécessaire et même indispensable à la fois au développement de cette discipline, mais également à la reconnaissance de ses spécificités. Par la remise en question de certaines pratiques (thrombolyse pour les AVC mineurs, utilisation de facteurs de la coagulation pour le polytraumatisé sévère), l’accès à de nouvelles technologies (vidéo-laryngoscopie, troponines POCT en préhospitalier) ou le questionnement sur de nouvelles pratiques (double défibrillation, US pulmonaire dans la pneumonie), la recherche permet aux urgentistes d’adapter leur pratique quotidienne à l’état de l’art.
856-7
63-66
20
17
Janvier
RMS0856-7-013
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
médecine d'urgence
hôpitaux
laryngoscopes
polytraumatisme
accident vasculaire cérébral

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Néphrologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231104
https://doi.org/10.53738/REVMED.2024.20.856-7.67
De Seigneux S
Haidar F
Jaques D
Masson G
Nachit M
Saudan P
10.53738/REVMED.2024.20.856-7.67
Molecules such as sparsentan and budesonide look promising to treat proteinuric IGA nephropathy. SLGT2 inhibitors have a prominent place in nephroprotection and could be used in the treatment of acute kidney injury due to heart failure as well. High volume hemodiafiltration compared to hemodialysis improves survival in dialysis patients. Lessening dialysate temperature does not improve hemodynamic stability during the dialysis session. Sodium bicarbonate does not seem to protect renal function in renal transplant patients. SGLT2 inhibitors may have a beneficial effect in these patients in terms of nephroprotection.Dans les formes protéinuriques de néphropathie à IgA, le sparsentan et le budésonide semblent être des molécules prometteuses. Les inhibiteurs du SGLT2 (iSGLT2) confirment leur place primordiale dans la néphroprotection et pourraient être utilisés dans le traitement de l’insuffisance rénale aiguë (IRA) liée à l’insuffisance cardiaque. En hémodialyse, l’hémodiafiltration à haut-débit comparée à l’hémodialyse diminue la mortalité d’environ 22 %. Abaisser la température du dialysat n’améliore pas la stabilité cardiovasculaire durant la séance d’hémodialyse. Le bicarbonate de sodium ne semble pas avoir d’effet néphroprotecteur sur la fonction rénale des greffés rénaux alors que les iSGLT2 pourraient avoir un effet bénéfique.
856-7
67-71
20
17
Janvier
RMS0856-7-014
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
néphrologie
atteinte rénale aigüe
défaillance cardiaque
transplantation rénale
dialyse rénale

---
Neurologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231105
https://doi.org/10.53738/REVMED.2024.20.856-7.72
Pizzarotti B
Buhler-Heintze A
Allali G
Rouaud O
Bally J
Michel P
Hirt L
Théaudin M
Pot Kreis C
Ryvlin P
Sokolov A
Rossetti A
Novy J
Du Pasquier R
10.53738/REVMED.2024.20.856-7.72
The year 2023 is marked by the arrival on the market of lecanemab for the treatment of Alzheimer's disease. New biomarkers have demonstrated their usefulness in monitoring peripheral neuropathies and diagnosing synucleinopathies. A genetic study has highlighted the role of nervous system cells in the risk of progression of multiple sclerosis (MS). The adverse effects of anticonvulsant treatments after prenatal exposure and on lipid metabolism have been clarified. New anti-CGRP treatments have demonstrated their efficacy in migraine attacks and chronic migraines. The criteria for thrombectomy have been further broadened. And finally, rehabilitation is refining the management of cerebrovascular patients and those with secondary progressive MS.L’année 2023 est marquée par l’arrivée sur le marché du lécanémab pour le traitement de la maladie d’Alzheimer. De nouveaux biomarqueurs ont démontré leur utilité dans le suivi des neuropathies périphériques ou dans le diagnostic des synucléinopathies. Une étude génétique a mis en évidence le rôle des cellules du système nerveux dans le risque de progression de la sclérose en plaques (SEP). Les effets indésirables des traitements anticonvulsivants lors d’exposition prénatale ou sur le métabolisme des lipides ont été précisés. De nouveaux traitements anti-CGRP ont démontré leur efficacité dans les crises migraineuses et les migraines chroniques. Les critères de thrombectomie se sont encore élargis. Et enfin, la réhabilitation affine la prise en charge des patients cérébrovasculaires et de ceux atteints d’une SEP secondaire progressive.
856-7
72-75
20
17
Janvier
RMS0856-7-015
publication papier
Accès restreint
résumé en anglais
article de périodique
anticonvulsivants
Femelle
grossesse
humains
neuropathies périphériques
neurologie
médecine
maladie d'Alzheimer

---
Nutrition-obésité. Nouveau programme ciblant les enjeux comportementaux de la perte de poids à l’aide de la chirurgie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231106
https://doi.org/10.53738/REVMED.2024.20.856-7.76
Somers F
Toumanova A
Lanza Von Haller L
Campos S
Jung MK
Pataky Z
10.53738/REVMED.2024.20.856-7.76
Bariatric surgery is an effective treatment to improve metabolic health as long as behavioural changes are made. Opting for this therapeutic choice represents a real commitment on the part of patients which is complementary to the informative bariatric surgery consultation. After all, what practitioner has not been confronted with an urgent request from patients suffering from obesity who are over-investing in this operation? Therapeutic Patient Education offers the opportunity to work with patients to develop their status as committed actors through a new outpatient educational program. Increased feelings of self-efficacy and socio-cognitive conflict are ingredients that allow patients to invest in long-term changes.Pour perdre du poids en situation d’obésité, la chirurgie bariatrique est un traitement efficace améliorant la santé métabolique sous réserve de changements comportementaux. Opter pour ce choix thérapeutique représente un véritable travail sur l’engagement des patients qui s’inscrit en complément de la consultation informative de chirurgie bariatrique. En effet, quel praticien n’a-t-il pas été confronté à l’impasse d’une demande urgente par des patients en souffrance surinvestissant cette intervention ? L’éducation thérapeutique du patient offre l’opportunité de travailler avec les patients à leur statut d’acteur engagé au travers d’un nouveau programme éducatif ambulatoire. L’augmentation du sentiment d’auto-efficacité et le conflit sociocognitif sont des ingrédients qui permettent aux patients en réflexion d’investir les changements à long terme.
856-7
76-79
20
17
Janvier
RMS0856-7-016
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
obésité
état nutritionnel
Chirurgie bariatrique
perte de poids
patients en consultation externe

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Oncologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231107
https://doi.org/10.53738/REVMED.2024.20.856-7.80
Jankovic J
Abdelhamid K
Berthold D
Desbaillets N
Bouchaab H
Dei Tos G
Demicheli R
Diciolla A
Digklia A
Ferraro DA
Florez L
Galli-Vareia I
Hottinger A
Latifyan S
Liapi A
Mederos N
Giacomuzzi Moore B
Sakr R
Stamatiou A
Wagner AD
Peters S
Sarivalasis A
Vanniere F
Zaman K
Stravodimou A
10.53738/REVMED.2024.20.856-7.80
The oncology field continues its remarkable evolution over the years, with promising advances leading to innovative and individualized treatments. The development of new molecules, the identification of new therapeutic targets and the search for new sequences or combinations promise to revolutionize cancer treatments and contribute to improving survival rates, patients' quality of life and to open new perspective in oncology research. In this article, the newest data released in 2023 are reviewed.Le domaine de l’oncologie poursuit son évolution remarquable au fil des années, avec des avancées prometteuses ouvrant la voie à des traitements novateurs et individualisés. L’élaboration de nouvelles molécules, l’identification de nouvelles cibles thérapeutiques et la recherche de nouvelles séquences ou combinaisons de traitements promettent de révolutionner la prise en charge du cancer et de contribuer à améliorer les taux de survie, la qualité de vie des patients et à ouvrir de nouvelles perspectives dans la recherche en oncologie. Dans cet article, les nouveautés parues en 2023 sont passées en revue.
856-7
80-87
20
17
Janvier
RMS0856-7-017
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
qualité de vie
oncologie médicale

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ORL. Endoscopie du sommeil induit par les médicaments (DISE): indications et bénéfices.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231108
https://doi.org/10.53738/REVMED.2024.20.856-7.88
Schürmann G
Liu M
Glasson N
Chatelain S
Lambercy K
10.53738/REVMED.2024.20.856-7.88
Obstructive sleep apnea (OSA) is a common condition that can cause daytime or nocturnal symptoms with long-term impact on the patient's health. Various therapies and surgeries have been introduced over the years, and patient wishes and compliance are essential factors in the success of treatment. Drug-induced sleep endoscopy (DISE) is a procedure that assesses the opening and closing of the upper airway in real time. This article summarizes the indications and contraindications of DISE, with a review of sedation methods and the VOTE classification system, in order to facilitate the use of a common nomenclature based on a protocol applied at the CHUV.Le syndrome d’apnées obstructives du sommeil (SAOS) est une affection courante pouvant provoquer des symptômes diurnes ou nocturnes ayant un impact à long terme sur la santé du patient. Diverses thérapies et chirurgies ont été introduites au fil des années et les souhaits des patients et l’observance thérapeutique sont des facteurs essentiels dans le succès du traitement. L’endoscopie du sommeil induit par les médicaments (DISE: drug-induced sleep endoscopy) permet d’évaluer l’ouverture et la fermeture des voies respiratoires supérieures en temps réel. Cet article résume les indications et contre-indications de la DISE avec un rappel des méthodes de sédation et le système de classification VOTE, afin de faciliter l’utilisation d’une nomenclature commune basée sur un protocole appliqué au CHUV.
856-7
88-91
20
17
Janvier
RMS0856-7-018
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
endoscopie
anesthésie
larynx
sommeil

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Pédiatrie. Consultation en pédiatrie pour les enfants victimes de violence conjugale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231109
https://doi.org/10.53738/REVMED.2024.20.856-7.92
Sangsue J
Sandoz V
Kabwiku E
Depallens S
10.53738/REVMED.2024.20.856-7.92
Exposure to domestic violence affects a significant number of minors and is recognized as psychological abuse of children, with harmful consequences for their health in the absence of protection. The identification of such situations by professionals remains a major challenge, given the culture of secrecy that often prevails in such circumstances. When the situation of children or adolescents exposed to domestic violence is known, it is essential to set up an assessment. A brief intervention led by psychologists has recently been developed within the CHUV's Pediatrics Department. Considering the family context and the type of violence, this service assesses the needs of minors and guides them, placing them at the heart of the support process.L’exposition à la violence conjugale concerne un nombre important de mineurs et est reconnue comme une maltraitance psychologique envers les enfants, avec des conséquences néfastes pour leur santé en l’absence de protection. Le repérage de ces situations par des professionnels demeure un défi majeur en raison de la culture du secret qui règne souvent dans ces circonstances. Lorsque la situation d’enfants ou d’adolescents exposés à la violence conjugale est connue du médecin, il est essentiel de mettre en place une évaluation. Une intervention brève conduite par des psychologues a récemment été développée au sein du Service de pédiatrie du CHUV. Tenant compte du contexte familial et du type de violences, cette prestation met l’accent sur l’évaluation des besoins des mineurs et sur leur orientation, en les plaçant au centre de la démarche de soutien.
856-7
92-95
20
17
Janvier
RMS0856-7-019
publication papier
Accès restreint
résumé en anglais
article de périodique
adolescent
enfant
humains
violence domestique
coeur
orientation vers un spécialiste

---
Pharmacovigilance. Sevrage et effet rebond: pas seulement avec les psychotropes.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231110
https://doi.org/10.53738/REVMED.2024.20.856-7.96
Marouf R
Chtioui H
Girardin FR
Buclin T
Diezi L
10.53738/REVMED.2024.20.856-7.96
The list of drugs whose abrupt discontinuation is likely to induce withdrawal symptoms or a rebound in the pathology being treated is not limited to psychotropic drugs. It includes a number of somatic drugs (e.g. proton pump inhibitors, opioids, triptans, fingolimod, corticosteroids, antiepileptics, nootropics, antiparkinsonians, denosumab, beta-blockers, laxatives, nasal vasoconstrictors, etc.). This type of unintended effect, often underestimated, generally results from a drug-induced homeostatic imbalance that persists after the drug has been discontinued. Taking this risk into account right from the initial prescription should make it possible to prevent such complications, by encouraging intermittent use of the drug, or by applying a very gradual reduction in dosage when a regular treatment is stopped.La liste des médicaments dont l’arrêt brusque est susceptible d’entraîner des symptômes de sevrage ou un rebond de la pathologie traitée ne se limite pas aux psychotropes, mais inclut un certain nombre de médicaments somatiques (inhibiteurs de la pompe à protons, opioïdes, triptans, fingolimod, corticostéroïdes, antiépileptiques, nootropes, antiparkinsoniens, dénosumab, bêtabloquants, laxatifs, vasoconstricteurs nasaux, etc.). Ce type d’effet indésirable, souvent méconnu, résulte en général d’un déséquilibre homéostatique causé par le médicament, persistant après son interruption. La prise en compte de ce risque dès la prescription initiale devrait permettre de prévenir ces complications, en privilégiant un recours intermittent au médicament ou en prévoyant une diminution très progressive des posologies au moment de mettre un terme à un traitement continu.
856-7
96-101
20
17
Janvier
RMS0856-7-020
publication papier
Accès restreint
résumé en anglais
article de périodique
psychoanaleptiques
analgésiques morphiniques
anticonvulsivants
humains
pharmacovigilance
psychoanaleptiques

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Rhumatologie: ce qui a changé en 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231111
https://doi.org/10.53738/REVMED.2024.20.856-7.102
Lauper K
Finckh A
Genevay S
Girard-Guyonvarc'h C
Guemara R
Nissen MJ
Iudici M
10.53738/REVMED.2024.20.856-7.102
In rheumatology, this year has been characterized by a broader knowledge of the pathogenesis of rheumatoid arthritis and mechanisms involved in the onset and persistence of low back pain. Studies relevant to the management of of gout, axial spondyloarthritis, autoinflammatory diseases and systemic vasculitides were published. New data on the safety of JAK inhibitors have been published. The ASAS-EULAR recommendations for the treatment of axial spondyloarthritis were updated, and the 2023 EULAR/PReS guidelines for the diagnosis and treatment of systemic juvenile idiopathic arthritis and adult-onset Still's disease are now available. New molecules and different glucocorticoid sparing strategies were introduced for giant cell arteritis.En 2023, en rhumatologie, une avancée des connaissances sur la pathogenèse de la polyarthrite rhumatoïde et des mécanismes impliqués dans l’apparition et la persistance des lombalgies a été notée. Des études relevantes pour le traitement de la goutte, de la spondylarthrite axiale, des maladies auto-inflammatoires et des vascularites systémiques ont été publiées. De nouvelles données concernant la sécurité des inhibiteurs de Janus kinase sont disponibles. Les directives ASAS-EULAR pour le traitement de la spondylarthrite axiale ont été actualisées et les recommandations EULAR/PReS 2023 pour le diagnostic et le traitement de l’arthrite juvénile idiopathique systémique et de la maladie de Still de l’adulte sont désormais disponibles. De nouvelles molécules et différentes stratégies d’épargne des glucocorticoïdes ont été proposées pour l’artérite à cellules géantes.
856-7
102-105
20
17
Janvier
RMS0856-7-021
publication papier
Accès restreint
résumé en anglais
article de périodique
adulte
humains
rhumatologie
arthrite juvénile
polyarthrite rhumatoïde
artérite à cellules géantes
artérite à cellules géantes

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Supplémentation en thiamine pendant le sevrage alcoolique: relation entre dose, voie d’administration et fonction cognitive.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231112
https://doi.org/10.53738/REVMED.2024.20.856-7.106
Amana E
10.53738/REVMED.2024.20.856-7.106
856-7
106
20
17
Janvier
RMS0856-7-022
publication papier
Accès restreint
actualités
humains
alcoolisme
syndrome de sevrage
cognition
compléments alimentaires

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Candide et les réalités non ordinaires.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231113
https://doi.org/10.53738/REVMED.2024.20.856-7.106
Martin J
10.53738/REVMED.2024.20.856-7.106
856-7
106-107
20
17
Janvier
RMS0856-7-023
publication papier
Accès restreint
lettre

---
Pilule contraceptive: gare aux AINS.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231114
https://doi.org/10.53738/REVMED.2024.20.856-7.107
Abellan C
10.53738/REVMED.2024.20.856-7.107
856-7
107
20
17
Janvier
RMS0856-7-024
publication papier
Accès restreint
actualités
contraceptifs
anti-inflammatoires non stéroïdiens
humains

---
Protéger le monde, mais quel monde ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231115
https://doi.org/10.53738/REVMED.2024.20.856-7.108
Kiefer B
10.53738/REVMED.2024.20.856-7.108
856-7
108
20
17
Janvier
RMS0856-7-025
publication papier
Accès restreint
éditorial

---
Vaccination ARN messager (ARNm), modèle de transition de la biologie fondamentale à la médecine.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38231390
https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.129
https://doi.org/10.5802/crbiol.129
Sansonetti PJ
10.5802/crbiol.129
Sixty years elapsed between the discovery of messenger RNA (mRNA) and the use of this molecule in an unprecedented global vaccination campaign that brought the Covid-19 pandemic under control. Sixty years of doubts for some and certainties for others about the possibility of using mRNA-an example of synthetic biology-in therapeutic medicine and vaccinology. Years of translational research and development have culminated in the success of anti-Covid-19 mRNA vaccines and the promise of more to come against emerging pathogens. A new paradigm in vaccinology, enabling pandemics to be tackled as they emerge. A lesson to be learned: medical progress is less a question of time than of the critical nature of the biological discovery that underpins it. Before leaving us, François Gros, who played a key role in the discovery of mRNA, was able to appreciate the relevance of this obvious fact.Soixante ans ont séparé la découverte de l’ARN messager (ARNm) et l’utilisation de cette molécule dans une campagne planétaire inédite de vaccination ayant permis le contrôle de la pandémie de Covid-19. Soixante ans de doutes chez certains et de certitudes chez d’autres sur la possibilité d’utiliser l’ARNm — un exemple de biologie de synthèse — en médecine thérapeutique et en vaccinologie. Des années de recherche et de développement « translationnels » pour aboutir au succès de vaccins à ARNm anti-Covid-19 et à la promesse d’autres à venir contre de nouveaux pathogènes émergents. Un nouveau paradigme de la vaccinologie permettant d’attaquer les pandémies dans le temps de leur émergence. Une leçon à tirer, le progrès médical est moins affaire de temps que de la nature décisive de la découverte biologique qui le sous-tend. François Gros, acteur de la découverte de l’ARNm a pu, avant de nous quitter, juger de la pertinence de cette évidence.
S2
69-74
346
arnm; biologie synthétique; covid-19; vaccins
29
Mars
publication avant impression
Accès restreint
résumé en anglais
article de périodique
ARN messager
humains
pandémies
ARN messager
vaccination
biologie
article historique

---
Pathologie thyroïdienne. Actualités et problèmes pratiques. Introduction.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38233234
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00002-6
Guyétant S
10.1016/j.annpat.2023.12.009
2
90-91
44
16
Mars
S0242-6498(24)00002-6
publication avant impression
Accès restreint
article de périodique

---
Une curieuse lésion biphasique du sein.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38233235
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00004-X
Schoelinck J
Heinemann M
Pissaloux D
Franceschi T
Treilleux I
10.1016/j.annpat.2023.12.011
Adenomyoepithelioma represents 0.5% of breast tumors in postmenauposal women. Prognosis is good when the tumor is benign. However, its malignant variant is associated with a poor prognosis with local recurrences and metastatic potential. We present the case of a malignant adenomyoepithelioma, expose the 2019 WHO classification issues and propose a classification in three categories: benign, atypical and malignant adenomyoepitheliomas (in situ and invasive).
adénomyoépithéliome atypique; adénomyoépithéliome malin; atypical adenomyoepithelioma; epithelial/myoepithelial proliferation; malignant adenomyoepithelioma; prolifération épithéliale/myoépithéliale
16
Janvier
S0242-6498(24)00004-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Bethesda 2023: nouvelle terminologie en cytopathologie thyroïdienne.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38233236
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(23)00236-5
Cochand-Priollet B
Vielh P
10.1016/j.annpat.2023.12.008
A third update of The Bethesda System for Reporting Thyroid Cytopathology has been published in 2023 following the first (2010) and second (2017) versions. The main modifications are the following 1) a new co-Editor, 2) 4 associate editors, 3 of them from Europe, 3) the inclusion of 65 co-authors, 19 of them from Europe, 4) 2 new chapters: one dealing with pediatrics thyroid cytopathology and the other one describing molecular cytopathology profiling, 5) updated risks of malignancy (ROM), 6) a terminology in line with the 2022 WHO classification of thyroid tumors, 7) diagnostic categories now defined by a unique name, 8) 2 subtypes in the Atypia of Undetermined Significance category with corresponding ROM.
1
30-35
44
cytopathologie; cytopathologie moléculaire; cytopathology; molecular cytopathology; terminologie; terminology; thyroid; thyroïde
16
Février
S0242-6498(23)00236-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
enfant
cytoponction
tumeurs de la thyroïde
tumeurs de la thyroïde
nodule thyroïdien
nodule thyroïdien
adénocarcinome folliculaire
études rétrospectives

---
Intérêt des réunions de concertation pluridisciplinaires dédiées à l’endométriose : à partir d’une série de 682 patientes.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38237734
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00009-6
Osada M
Faller E
Lecointre L
Boisrame T
Martel C
Gabriele V
Akladios C
Host A
10.1016/j.gofs.2024.01.005
AbstractText Label OBJECTIVE We decided to conduct a study based on these multidisciplinary team (MDT) in order to investigate their impact at the University Hospitals of Strasbourg and look for ways to improve this MDT. /AbstractText AbstractText Label METHODS This is a retrospective study of the 682 patients presented to endometriosis MDT from its inception in March 2017 to December 2020 Results: The MDT decision was different from that initially proposed by the patient's referent for 406 patients (60%). Surgery was chosen for 417 patients (61%) and assisted reproduction for 261 patients (38%). A review of the MRI by a referring radiologist was carried out for 348 cases (51%), with a modification of the results for 255 patients (73%). Initial underestimation of lesions was noted in 198 cases. /AbstractText AbstractText Label CONCLUSION Our study has shown the importance of MDT in endometriosis, since the therapeutic proposal was modified in 60% of cases. In addition, we supported the importance of radiologists specializing in this field, since they made a modification in two-thirds of the MRIs reread. These results show the importance of collegial discussions, which can modify the decisions of medical teams. This underlines the importance of setting up endometriosis networks. /AbstractText
endométriose; chirurgie; endometriosis; infertility; infertilité; medically assisted procreation; multidisciplinary consultation meeting; procréation médicalement assistée; réunion de concertation pluridisciplinaire; surgery
16
Janvier
S2468-7189(24)00009-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Autogreffe de cellules souches périphériques dans la sclérodermie systémique : un progrès important, mais il faut tempérer notre enthousiasme !
2024
http://www.ncbi.nlm.nih.gov/pubmed/38238136
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00002-X
Mouthon L
10.1016/j.revmed.2024.01.001
Three prospective randomized studies have demonstrated the efficacy of autologous hematopoietic stem cell (HSC) transplantation in systemic sclerosis (SSc) on survival. These results encourage us to offer this therapy to patients who have a rapidly progressive disease and who have early symptoms but no advanced visceral involvement. HSC autograft can thus be discussed in patients with diffuse cutaneous SSc with a duration of the disease since the first visceral manifestations (cutaneous, cardiac, digestive, pulmonary, or renal) excluding Raynaud's phenomenon of less than 5 years. However, the indications for HSC autograft in SSc validated at European level and in the national diagnostic and care protocol (PNDS) are broader and some of these indications are debatable, in particular in patients with worsening diffuse interstitial lung disease. These indications are discussed in a reasoned way, taking into account the level of evidence and the toxicity of the HSC autograft.
2
100-103
45
interstitial lung disease; morbidity; mortality; peripheral stem cell transplantation; systemic scleroderma; autogreffe de cellules souches hématopoïétiques; morbidité; mortalité; pneumopathie interstitielle diffuse; sclérodermie systémique diffuse
17
Février
S0248-8663(24)00002-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
transplantation de cellules souches de sang périphérique
études prospectives
sclérodermie systémique
sclérodermie systémique
transplantation de cellules souches hématopoïétiques
transplantation autologue

---
What about a transmission of SARS-CoV-2 through a viral biofilm?
2023
http://www.ncbi.nlm.nih.gov/pubmed/38239024
https://www.jle.com/10.1684/vir.2023.1029
Thoulouze MI
Inizan C
10.1684/vir.2023.1029
6
85-88
27
01
Décembre
vir.2023.1029
publication papier
Accès restreint
article de périodique
humains

---
Et si le SARS-CoV-2 se transmettait sous forme de biofilm viral ?
2023
http://www.ncbi.nlm.nih.gov/pubmed/38239025
https://www.jle.com/10.1684/vir.2023.1027
Thoulouze MI
Inizan C
10.1684/vir.2023.1027
6
313-316
27
01
Décembre
vir.2023.1027
publication papier
Accès restreint
article de périodique
humains

---
Vincent Deubel.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38239026
https://www.jle.com/10.1684/vir.2023.1026
Desprès P
Flamand M
Stubljar I
Marianneau P
Murri S
Tordo N
10.1684/vir.2023.1026
6
317-319
27
01
Décembre
vir.2023.1026
publication papier
Accès restreint
article de périodique

---
Rôle des protéines HBe et HBc du virus de l’hépatite B dans l’hépatocarcinogenèse.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38239027
https://www.jle.com/10.1684/vir.2023.1025
Lefeuvre C
Ducancelle A
10.1684/vir.2023.1025
Chronic hepatitis B virus (HBV) infection is one of the most common factors associated with hepatocellular carcinoma (HCC). However, the pathogenesis of HBV-mediated hepatocarcinogenesis is not clearly defined. Persistence of HBV infection is associated with HCC pathogenesis, and various HBV proteins appear to be involved in promoting this persistence. Currently available data suggest that the core protein, a structural component of the viral nucleocapsid, and the HBe protein, a non-structural HBV protein that can act as both a tolerogen and an immunogen, play a potential role in the development of HCC. Research shows that both proteins are capable of disrupting various pathways involved in liver carcinogenesis, including the sustenance of proliferative signaling, resistance to cell death, tumor-promoting inflammation and avoid immune destruction. This review summarizes the various signaling pathways by which HBc and HBe proteins (and their precursors) can promote hepatocarcinogenesis.
6
320-332
27
core protein; hepatitis b e protein; hepatitis b virus; hepatocarcinogenesis; hepatocellular carcinoma; signaling pathways
01
Décembre
vir.2023.1025
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
virus de l'hépatite B
carcinome hépatocellulaire
carcinome hépatocellulaire
tumeurs du foie
tumeurs du foie
tumeurs du foie
hépatite B chronique
carcinogenèse

---
Le virome cutané : de la virologie à la médecine personnalisée.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38239028
https://www.jle.com/10.1684/vir.2023.1028
Dominguez-Lafage C
Laganà M
Gesbert F
Marin-Esteban V
Schlecht-Louf G
Bachelerie F
Deback C
10.1684/vir.2023.1028
The virome of the skin, defined as all viruses detected in the skin, represents a significant part of the microbiota. A much more recent discovery than the bacterial flora, the existence of the cutaneous virome has been revealed by recent metagenomic studies. The normal human skin virome is dominated by bacteriophages, Papillomaviridae, whose genomic diversity has proved extraordinary, and Polyomaviridae. Many yet unknown viral genomes within this virome await identification. The composition of the virome of the skin has been shown to be strictly individual and relatively stable over time, resulting from adaptation to everyone's genetics, lifestyle and mechanisms of immunological tolerance finely selected over the course of evolution. Yet little studied, the virome of the skin and all its interactions with other microbiota and the host are attracting growing interest. Indeed, constitutional or acquired alterations in the homeostasis between the commensal virome and the skin, ranging from sub-clinical viral dysbiosis to severe transformation of keratinocytes or adnexal cells, have been observed. These recent observations are stimulating the search for innovative solutions aimed at measuring or even modulating its pathological expression, with a view to personalized medicine.
6
333-354
27
papillomavirus; polyomavirus; skin; virome
01
Décembre
vir.2023.1028
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
Médecine de précision
virus
bactériophages
peau

---
Appel à candidatures : ANRS Maladies infectieuses émergentes, Société française de virologie (SFV).
2023
http://www.ncbi.nlm.nih.gov/pubmed/38239029
https://www.jle.com/10.1684/vir.2023.1030
10.1684/vir.2023.1030
6
355-356
27
01
Décembre
vir.2023.1030
publication papier
Accès restreint
article de périodique

---
Lumière bleue et implants intraoculaires : croyances et réalités.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38241770
https://linkinghub.elsevier.com/retrieve/pii/S0181-5512(23)00575-2
Desmettre T
Baillif S
Mathis T
Gatinel D
Mainster M
10.1016/j.jfo.2023.104043
The first intraocular lenses (IOLs) used for cataract surgery transmitted both ultraviolet (UV) radiation and visible light to the retina. Colorless UV-blocking IOLs were introduced and rapidly adopted in the 1980s. Yellow-tinted blue-blocking (also known as blue-filtering) IOLs were marketed in the early 1990s. Blue-blocking IOLs were intended to simulate age-related crystalline lens yellowing to reduce the cyanopsia that some patients experienced after cataract surgery. When blue-filtering IOLs were introduced in North America, however, blue-blocking chromophores were advocated as a way to protect patients from age-related macular degeneration (AMD) despite the lack of evidence that normal environmental light exposure causes AMD. The blue light hazard is a term that describes the experimental finding that acute, abnormally intense light exposures are potentially more phototoxic to the retina when short rather than long wavelengths are used. Thus, in brief exposures to intense light sources such as welding arcs, ultraviolet radiation is more hazardous than blue light, which is more hazardous than longer wavelength green or red light. International commissions have cautioned that the blue light hazard does not apply to normal indoor or outdoor light exposures. Nonetheless, the hazard is used for commercial purposes to suggest misleadingly that ambient environmental light can cause acute retinal phototoxicity and increase the risk of AMD. Very large epidemiological studies show that blue-blocking IOLs do not reduce the risk or progression of AMD. Additionally, blue-filtering IOLs or spectacles cannot decrease glare disability, because they decrease image and glare illuminance in the same proportion. Blue light is essential for older adults' scotopic photoreception needed to reduce the risk of nighttime falling and related injuries. It is also critical for circadian photoreception that is essential for good health, sleep and cognitive performance. Unfortunately, age-related pupillary miosis, retinal rod and ganglion cell photoreceptor degeneration and decreased outdoor activity all reduce the amount of healthful blue light available to older adults. Blue-restricting IOLs further reduce the available blue light at a time when older adults need it most. Patients and ophthalmologists are exposed to hypothesis-based advertisements for blue-filtering optical devices that suppress short wavelength light critical for vision in dim lighting and for good physical and mental health. Spectacle and intraocular lens selections should be based on scientific fact, not conjecture. Ideal IOLs should improve photoreception rather than limit it permanently. Practice efficiency, surgical convenience and physician-manufacturer relationships may eliminate a patient's opportunity to choose between colorless blue-transmitting IOLs and yellow-tinted, blue-restricting IOLs. Cataract surgeons ultimately determine whether their patients have the opportunity to make an informed choice about their future photoreception.
2
104043
47
age; blue light; cataract; cataracte; chirurgie; cristallin; dégénérescence maculaire liée à l’âge/épidémiologie; lens; light; lumière; macular degeneration/epidemiology; prevention; prévention; surgery; vieillissement; control; contrôle; lumière bleue
18
Février
S0181-5512(23)00575-2
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
sujet âgé
rayons ultraviolets
lentilles intraoculaires
lumière
dégénérescence maculaire
dégénérescence maculaire
dégénérescence maculaire
troubles de la vision
cataracte

---
La littératie en santé : un concept à s’approprier.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242611
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00388-3
Kinuthia G
10.1016/j.revinf.2023.11.003
297
1
73
Janvier
S1293-8505(23)00388-3
publication papier
Accès restreint
éditorial
humains
compétence informationnelle en santé

---
La chirurgie non programmée en traumatologie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242612
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00389-5
Benazzouz M
10.1016/j.revinf.2023.11.004
297
15
73
Janvier
S1293-8505(23)00389-5
publication papier
Accès restreint
éditorial
humains

---
L’accueil du patient traumatisé grave.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242613
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00390-1
Mougne A
Ancelot L
10.1016/j.revinf.2023.11.005
Severe trauma accounts for around 15% of all traumas, but remains the leading cause of death in people under 45. The organization of networked care for severe trauma is becoming a necessity in France. Thanks to this kind of organization, it is possible to speed up the care of these patients, and optimize their referral to the most appropriate reception center. The Bicêtre University Hospital (CHU) is one of six trauma centers in the Île-de-France region, all working to the same specifications set out by the Île-de-France regional health agency.
297
16-18
73
choc hémorragique; défaillance vitale; hemorrhagic shock; nursing care; prise en charge infirmière; severe trauma; trauma center; traumatisé sévère; vital failure
Janvier
S1293-8505(23)00390-1
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
France
centres de traumatologie

---
L’organisation au bloc opératoire des urgences.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242614
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00391-3
Chateau L
10.1016/j.revinf.2023.11.006
The structure and organization of operating theatres vary from one healthcare facility to another. Some establishments have a multi-disciplinary operating theatre, with shared operating theatres and staff, while others have separate operating theatres, often divided by discipline. Emergencies are therefore dealt with in the operating theatres for scheduled surgery. However, some university hospitals also have emergency operating theatres.
297
19-20
73
bloc opératoire; care; chirurgie; emergency; operating theatre; organisation; organization; prise en charge; surgery; urgence
Janvier
S1293-8505(23)00391-3
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
blocs opératoires
service hospitalier d'urgences
hôpitaux universitaires

---
Prise en charge en urgence d’un patient jeune victime du syndrome de la queue-de-cheval.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242615
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00392-5
Jean-Baptiste Y
10.1016/j.revinf.2023.11.007
A 31-year-old man was brought to the emergency department because, for the past two days, he had been experiencing paresthesia-like sensory disturbances in his lower limbs, with dorsal pain that was not relieved by analgesics, as well as the appearance of sphincter disturbances and increasing difficulty in mobilization due to balance disturbances and pain. Presentation of this clinical case.
297
21-23
73
emergency; management; paresthesia; paresthésie; ponytail syndrome; prise en charge; sensory disturbance; syndrome de la queue-de-cheval; trouble sensitif; urgence
Janvier
S1293-8505(23)00392-5
publication papier
Accès restreint
résumé en anglais
article de périodique
présentations de cas
Mâle
humains
adulte
syndrome
douleur

---
Retour d’expérience sur un circuit dédié pour la chirurgie non programmée.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242616
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00393-7
Chrif K
10.1016/j.revinf.2023.11.008
A few months ago, the Pitié-Salpêtrière orthopedics department set up a specific circuit for trauma patients. Here's a look back at this innovation, which highlights the importance of multidisciplinary work for patients.
297
24-25
73
chirurgie non programmée; circuit dédié; coordination; dedicated circuit; multidisciplinary staff; staff pluridisciplinaire; trauma emergency; unscheduled surgery; urgence traumatologique
Janvier
S1293-8505(23)00393-7
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
rétroaction
procédures orthopédiques
plaies et blessures

---
Le rôle de l’assistant social en service d’orthopédie et traumatologie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242617
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00394-9
Pèdre A
10.1016/j.revinf.2023.11.009
Trauma patients often lose their autonomy in the aftermath of an accident. This handicap adds to the burden of other social problems that pre-existed the trauma. The social worker's role with these patients is therefore essential.
297
26-27
73
city-hospital coordination; coordination ville-hôpital; multidisciplinarity; pluridisciplinarité; precariousness; prise en charge sociale; précarité; social care; traumatologie; traumatology; vulnerability; vulnérabilité
Janvier
S1293-8505(23)00394-9
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
traumatologie
orthopédie

---
La formation par simulation in situ des équipes médico-chirurgicales à la prise en charge des traumatisés sévères.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242618
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00395-0
Paris R
de Lesquen H
Bernaudon É
Chouvier J
Martin É
10.1016/j.revinf.2023.11.010
In the management of severe trauma, the aim is to assess the patient's clinical stability as quickly as possible, enabling referral to imaging (whole-body CT scan, embolization if necessary) or the operating room, or even the decision to perform in situ surgery (resuscitation thoracotomy). To cope with these critical situations, team training is essential, with the aim of ensuring the reproducibility of the difficulties encountered. High-fidelity in situ simulation is the ideal tool for meeting this training challenge.
297
28-29
73
crew ressource management; crew resource management; debriefing; débriefing; immersion; leadership; life-threatening emergency; realism; réalisme; simulation; teamwork; travail d’équipe; urgence vitale
Janvier
S1293-8505(23)00395-0
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
reproductibilité des résultats
compétence clinique
équipe soignante
réanimation

---
La place du psychologue dans le service d’orthopédie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242619
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00396-2
Medina O
10.1016/j.revinf.2023.11.011
The essential place of the psychologist in the orthopedics department of Pitié-Salpêtrière is to relieve the suffering of polytraumatized patients, to work in a multidisciplinary manner, to participate in the staff of the department to have complete information of the patients, to give an informed opinion on the psychological state of the patient, so as to help in the discussion for making decisions on their trajectory. The role of the psychologist is part of the overall care of patients, care which sometimes extends to the family, the patient's loved ones and the teams who care for them.
297
30-31
73
accompagnement; accompaniement; altered body image; altération de l’image corporelle; post-traumatic stress; stress post-traumatique; trauma; traumatisme
Janvier
S1293-8505(23)00396-2
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
anxiété
orthopédie
psychologie
polytraumatisme

---
Cerner les besoins du patient ou du résident.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242620
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00397-4
Forest B
10.1016/j.revinf.2023.11.012
Patients, residents, all have needs linked to their situation. Identifying them makes it possible to increase their physical or psychological comfort and thus improve the quality of the caregiver-patient relationship. This objective requires increased attention, particularly towards requests, behaviors, and emotions.
297
32-34
73
besoin; bien-être; comfort; communication; confort; emotion; healer-healed relationship; need; relation soignant-soigné; well-being; émotion
Janvier
S1293-8505(23)00397-4
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
émotions
Relations entre professionnels de santé et patients

---
États des lieux des plateformes de transition ado-adulte.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242621
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00398-6
Bourgninaud M
Bottius S
Madaoui F
Dupont F
Castillo M
Clair A
10.1016/j.revinf.2023.11.013
Transition support is an integral part of the care of adolescents in clinical services. To avoid disruptions in the care pathway, transition spaces in pediatric and adult hospitals are emerging. There are currently fifteen in France. The professionals working there and the tools and methods used are heterogeneous, but with a common challenge which is the reduction of the major risk of disruption of the care pathway and support for the life course.
297
35-38
73
adolescence; chronic pathology; disability; handicap; jeune adulte; pathologie chronique; plateforme de transition; transition; transition platform; young adult
Janvier
S1293-8505(23)00398-6
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
adulte
humains
enfant
adolescent
transition aux soins pour adultes
hôpitaux
France

---
Visibilité des patients et respect de leur intimité : concilier des impératifs apparemment contraires en service de réanimation.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242622
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00399-8
Aparicio C
Lemaire-Brunel D
Siami S
10.1016/j.revinf.2023.11.014
Rigorous monitoring of vital functions in intensive care requires optimal visibility of patients and their environment. Conversely, respect for privacy is an ethical imperative to respect. Liquid crystal electrical film is a device that can be applied to windows and can take opaque or transparent form on demand. Its use could satisfy the visibility of patients and respect for their privacy.
297
39-40
73
dignity; dignité; film à cristaux liquides; intensive care unit; intimité; liquid crystal film; privacy; unité de soins intensifs; visibility; visibilité
Janvier
S1293-8505(23)00399-8
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
vie privée
unités de soins intensifs
Soins de réanimation
patients

---
Le partage culturel et relationnel dans la prise en charge des patients en Afrique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242623
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00400-1
Nouri E
Nzobadila-Loufouma D
Samassi M
Thiam BK
10.1016/j.revinf.2023.11.015
Nursing students from a nursing training institute (Ifsi) in Seine-Saint-Denis, we had the opportunity to experience an intercultural internship in Africa. It is this experience that we wish to convey through this article, by highlighting the cultural encounter and the richness of the various existing relationships, shared through this unique experience.
297
41-44
73
africa; afrique; compétence culturelle; cultural competence; interculturality; interculturalité; nursing student; relational care; soin relationnel; étudiant en soins infirmiers
Janvier
S1293-8505(23)00400-1
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
enseignement infirmier
Afrique
élève infirmier
internat et résidence
soins aux patients

---
La pratique avancée infirmière en France.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242624
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00401-3
Videloup L
10.1016/j.revinf.2023.11.016
297
45-46
73
Janvier
S1293-8505(23)00401-3
publication papier
Accès restreint
article de périodique
humains
France
soins

---
Le psychotraumatisme, conséquence des violences subies.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242625
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00402-5
Fourneau C
10.1016/j.revinf.2023.11.017
297
47-48
73
Janvier
S1293-8505(23)00402-5
publication papier
Accès restreint
article de périodique
humains
violence

---
De l’idée jusqu’à la valorisation de l’étude : retour d’expérience.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242626
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00403-7
Tomadesso C
10.1016/j.revinf.2023.11.018
297
49-50
73
Janvier
S1293-8505(23)00403-7
publication papier
Accès restreint
article de périodique
humains
rétroaction

---
Le bon usage des insulines.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242627
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00404-9
Landoas A
Grévy A
Trochet C
Baudrant M
Gibert P
Chanoine S
10.1016/j.revinf.2023.11.019
297
51-52
73
Janvier
S1293-8505(23)00404-9
publication papier
Accès restreint
article de périodique
insulines
humains
insulines

---
L’organisation des soins à l’heure du développement durable.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242628
https://linkinghub.elsevier.com/retrieve/pii/S1293-8505(23)00405-0
Masia S
10.1016/j.revinf.2023.11.020
297
53-54
73
Janvier
S1293-8505(23)00405-0
publication papier
Accès restreint
article de périodique
humains
prestations des soins de santé

---
La version 2022 du Système de Paris : quoi de neuf ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242741
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00003-8
Courtade-Saïdi M
10.1016/j.annpat.2023.12.010
The second version of the Paris System for reporting urine cytology was published in 2022. It follows the first version of 2016, which was very successful and widely adopted by many cytopathologists from different countries. Thus, numerous publications using the Paris System have made possible to refine the criteria as well as discussing the limits. The diagnostic accuracy of urinary cytology is high for detection of high-grade urothelial carcinoma, but not for low-grade carcinoma where there are few cytological abnormalities. So, the chapter individualizing low-grade urothelial neoplasms was deleted; the latter were included in the category negative for high-grade urothelial carcinoma. Indeed, the risk of malignancy is replaced by the risk of high-grade urothelial carcinoma. A new chapter has been devoted to urothelial tumors of the upper tract. Finally, the pitfalls linked to cellular degeneration are discussed for each category. The risk of high-grade malignancy associated with each category will help communication with the clinician and help patient care.
carcinome urothélial; cytologie urinaire; système de paris; the paris system; urinary cytology; urothelial carcinoma
18
Janvier
S0242-6498(24)00003-8
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
La thérapie cellulaire dans tous ses états.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38242769
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00005-5
Dougé A
Caux C
Bay JO
10.1016/j.bulcan.2024.01.001
Immunotherapy strategies have revolutionized the management of a significant number of patients in recent years, whether they are undergoing treatment for hematologic malignancies or solid tumors. This therapeutic class is extensive, ranging from antibodies targeting immune checkpoint molecules to adoptive cell therapy strategies, including bispecific antibodies and anticancer vaccines. All these strategies are currently in active development. Adoptive cell therapy involves the infusion of normal or genetically modified immune cells into a patient with the aim of restoring strong antitumor immunity, primarily associated with the cytotoxicity of T lymphocytes. Currently, there are three major adoptive cell therapy strategies: allogeneic hematopoietic stem cell transplantation, CAR-T cell therapy, and TCR-T cell therapy. The objective of this article is to describe the mechanisms of action of these three strategies as well as their current advantages, limitations and constraints.
2
213-221
111
allo-csh; allo-hsct; car-t cell; cell therapy; cellule car-t; cellule tcr-t; cytotoxic t cell; effet gvl; gvl effect; immunotherapy; immunothérapie; lymphocyte t cytotoxique; tcr-t cell; thérapie cellulaire
18
Février
S0007-4551(24)00005-5
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
transplantation de cellules souches hématopoïétiques
lymphocytes T
tumeurs hématologiques
immunothérapie adoptive
thérapie cellulaire et tissulaire

---
Évaluation d’une pratique d’auto-administration médicamenteuse mise en place dans un service de rééducation.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38244678
https://linkinghub.elsevier.com/retrieve/pii/S0003-4509(24)00004-X
Vanhaecke M
Hennion-Coussemacq M
Dervaux B
Accaoui P
Pruvost A
Ferret L
Lehmann L
Verryser F
Hiver Q
10.1016/j.pharma.2024.01.004
AbstractText Label UNLABELLED Objectives : Self-administration consists in the administration of medications by the patient himself during his hospitalization. The order of October 10, 2022 (1) modified the April 6, 2011 regulation to allow and regulate self-administration practices in hospital units. This evolution opens new perspectives for patient autonomy. The objective of this study is, firstly, to evaluate the rate of medication errors from patients under self-administration and secondly, to evaluate the satisfaction of patients and caregivers. /AbstractText AbstractText Label MATERIAL AND METHODS Eligible patients were recruited from a locomotor and polyvalent rehabilitation unit. After verification of eligibility, explanation given to the patient about the hospital self-administration of medication procedure and signature of the compliance agreement, patients started self-administration. Medication errors were reported during seven days. Evaluations of patient and staff satisfaction were also carried out. /AbstractText AbstractText Label RESULTS Of the 83 patients admitted to the care service, 32 were able to experiment self-administered medication procedure during their hospitalization. To assess the safety of this practice, 1235 drug intakes were analyzed. 94 administration errors were noted: 98% of them concerned analgesic drugs. All of these errors were omissions and none of them were rated as serious. The 20 patients questioned were all satisfied with self-administration. The 14 carers interviewed were satisfied with this change in practice. /AbstractText AbstractText Label CONCLUSION The medication self-administration process set up in the rehabilitation unit did not lead to serious medication errors. Patients and caregivers reported being satisfied with this new hospital practice. /AbstractText
2
329-341
82
: self-administration; auto-administration; evaluation des pratiques professionnelles; evaluation of professional practices; rehabilitation; rééducation
18
Mars
S0003-4509(24)00004-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique
préparations pharmaceutiques
humains
Erreurs de médication
hospitalisation
hôpitaux

---
Comment l’activité physique pourrait-elle réduire le risque de survenue et de récidive des cancers du sein ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38244776
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00008-4
Meneu A
Lavoué V
Guillermet S
Levêque J
Mathelin C
Brousse S
10.1016/j.gofs.2024.01.004
AbstractText Label OBJECTIVES Breast cancer is the most frequent and deadly cancer among women. In France, 50% of adults are currently overweight, mostly as a result of a sedentary lifestyle. Numerous studies have highlighted overweight, obesity and lack of physical activity as risk factors for the occurrence and prognosis of cancers, particularly breast cancer. The aim of this study was to understand the extent to which physical activity can improve this prognosis, and what the pathophysiology is. /AbstractText AbstractText Label METHODS The Senology Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF) based its responses on an analysis of the international literature using a Preferred Reporting Items for Systematic review and Meta-Analyses (PRISMA) methodology conducted on the PubMed database between 1994 and 2023. /AbstractText AbstractText Label RESULTS A total of 70 articles were selected, demonstrating the role of regular physical activity in reducing the risk of breast cancer occurrence and recurrence. This role in controlling carcinogenesis is mediated by metabolic factors such as leptin, adiponectin and insulin, sex hormones and inflammation. The signaling pathways deregulated by these molecules are known carcinogenic pathways which could be used as therapeutic targets adapted to this population, without replacing the essential hygienic-dietary recommendations. /AbstractText AbstractText Label CONCLUSION Physical activity has a protective effect on breast cancer risk and prognosis. We must therefore continue to raise awareness in the general population and promote physical activity as a means of primary, secondary, and tertiary prevention. /AbstractText
3
158-164
52
activité physique; breast cancer; cancer du sein; obesity; obésité; physical activity; prevention; prévention; sedentary lifestyle; sédentarité
18
Mars
S2468-7189(24)00008-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique
méta-analyse
adulte
humains
Femelle
tumeurs du sein
tumeurs du sein
surpoids
région mammaire
exercice physique
France

---
De 2023 à 2024 : consolider nos acquis, garder le cap de l’innovation et du progrès.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38245329
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00489-7
Vignot S
Pourquier P
l'Allemain G
Bay JO
comité de rédaction du Bulletin du Cancer
10.1016/j.bulcan.2023.12.005
1
1-2
111
Janvier
S0007-4551(23)00489-7
publication papier
Accès restreint
éditorial

---
Withdrawal notice to « Patients sous Palbociclib et hormonothérapie pour un cancer du sein métastatique : peut-on prédire la survenue d’une hématotoxicité précoce et sévère ? » [Bull Cancer 108 (2021) 544–552 https://doi.org/10.1016/j.bulcan.2021.01.007].
2024
http://www.ncbi.nlm.nih.gov/pubmed/38245330
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00446-0
Vazquez L
Arnaud A
Grenier J
Debourdeau P
10.1016/j.bulcan.2023.11.009
1
124
111
Janvier
S0007-4551(23)00446-0
publication papier
Accès restreint
erratum publié

---
L’année 2024 de la SFC.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38245331
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(23)00490-3
Rodrigues M
10.1016/j.bulcan.2023.12.006
1
3-4
111
Janvier
S0007-4551(23)00490-3
publication papier
Accès restreint
éditorial

---
Développement d’un outil d’évaluation de l’anxiété de performance en obstétrique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38246241
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00011-4
Andriamanjay D
Castel P
Ercole C
Bretelle F
Agostini A
Berbis J
Blanc J
10.1016/j.gofs.2024.01.007
AbstractText Label OBJECTIVE Developing a measuring tool for physician's performance anxiety during obstetrical procedures, as a self-administered questionnaire. /AbstractText AbstractText Label METHODS We used the Delphi method. First, we did a literature review to identify the items to submit for the first round. A panel of experts was asked to rate the relevance of items from one to six. For the first round of Delphi, items were retained if more than 70% of respondents assigned a five or six rating. Items were excluded if more than 70% of respondents assigned a one or two rating. All the other items, plus those suggested by the panel, were submitted to a second round of Delphi. The same item selection conditions were applied to the second round. /AbstractText AbstractText Label RESULTS The overall response rate to the Delphi was 79% (19 respondents). At the end of the first round, 14 items were consensually relevant, no item was consensually irrelevant. For the second round, the 18 items that did not find consensus and seven new items suggested by the experts in the first round were submitted. At the end of the second round, nine items were retained by consensus as relevant. /AbstractText AbstractText Label CONCLUSION This study defined by consensus 23 items for a self-questionnaire to measure specific performance anxiety in obstetrics divided into five dimensions: perceived stress, assessment of the risk of complications, medico-legal risk, impact of the healthcare team and peers, self-confidence and decision-making confidence. We intend to validate this tool in real population. /AbstractText
delphi technique; obstetrics; performance anxiety
19
Janvier
S2468-7189(24)00011-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Mésusage du paracétamol en soins primaires : étude transversale dans un contexte rural français.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38246801
Kinouani S
Vielle C
Lambert C
Dupouy J
Laporte C
10.1016/j.therap.2023.11.005
AbstractText Label OBJECTIVE To estimate the prevalence of the paracetamol use for a reason other than pain (qualitative misuse) during the last 12 months in patients consulting their general practitioner, as well as the reasons for this misuse. /AbstractText AbstractText Label METHODS Descriptive cross-sectional analysis, with gender weighting to estimate the prevalence of paracetamol misuse. /AbstractText AbstractText Label RESULTS In total, data from 209 patients were included in the analysis. Among them, 11 patients declared having taken paracetamol for a reason other than pain, i.e., a gender-weighted prevalence of 5.7% (95% CI: 3.0 to 10.4). Nearly two-thirds of these patients said they had done it to feel better. /AbstractText AbstractText Label CONCLUSIONS The paracetamol misuse is rare but real in general practice. Further studies are needed to better understand it, especially qualitative studies. /AbstractText
cross-sectional study; misuse; mésusage; paracetamol; paracétamol; primary care; soins primaires; étude transversale
29
Novembre
S0040-5957(23)00188-9
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Érythème polymorphe majeur associé à une infection au SRAS-CoV-2 chez un patient à la peau foncée.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38253367
http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=38253367
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805142
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38253367/
Pourghadiri A
Khosravi-Hafshejani T
Hong HC
10.1503/cmaj.230926-f
2
E61-E62
196
21
Janvier
196/2/E61
publication électronique
Accès restreint
article de périodique
humains
érythème polymorphe

---
Qu’est-ce qui motive les demandes d’AMM?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38253369
http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=38253369
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805143
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38253369/
Downar J
MacDonald S
Buchman S
10.1503/cmaj.230259-f
2
E69-E71
196
21
Janvier
196/2/E69
publication électronique
Accès restreint
article de périodique

---
Avis de décès pour décembre 2023.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38253370
http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=38253370
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805139
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38253370/
10.1503/cmaj.231668f
2
E72-E78
196
21
Janvier
196/2/E72
publication électronique
Accès restreint
article de périodique

---
Vaccination contre le SRAS-CoV-2 durant la grossesse.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38253371
http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=38253371
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805146
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38253371/
Dalcin D
Halperin SA
10.1503/cmaj.221556-f
2
E59-E60
196
21
Janvier
196/2/E59
publication électronique
Accès restreint
article de périodique
Femelle
grossesse
humains
vaccination

---
Faire tomber les obstacles à l’admission des personnes ayant un handicap en faculté de médecine au Canada.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38253372
http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=38253372
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805137
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38253372/
Gertsman S
Dini Y
Wilton D
Neilson S
10.1503/cmaj.230734-f
2
E63-E68
196
21
Janvier
196/2/E63
publication électronique
Accès restreint
article de périodique
humains
écoles de médecine
Canada
personnes handicapées
hospitalisation

---
L’antibiorésistance : un bon exemple du concept « une seule santé ».
2024
http://www.ncbi.nlm.nih.gov/pubmed/38259232
Jarlier V
10.5802/crbiol.139
Antibiotic resistance is the direct deleterious consequence of two synergistic causes linked to human activity: the massive use of antibiotics in human and animal health, which leads to the selection of the most resistant bacteria, and the spread of these selected resistant bacteria, directly by cross-transmission within human and animal populations and indirectly via the environment. The one health concept enables an integrated approach of the various components of the issue, linking human, animal and environmental ecosystems and their dynamics.La résistance aux antibiotiques est la conséquence délétère directe de deux causes synergiques liées à l’activité humaine : l’utilisation massive d’antibiotiques en santé humaine et animale, qui entraîne la sélection des bactéries les plus résistantes, et la dissémination des bactéries résistantes ainsi sélectionnées, directement par transmission au sein des populations humaines et animales (« transmission croisée »), et indirectement via l’environnement. Le concept « une seule santé » permet une approche intégrée des différentes composantes de la question, en permettant de relier les écosystèmes humains, animaux et environnementaux et leurs dynamiques.
antibiotiques; bactéries résistantes aux antibiotiques; une seule santé
23
Janvier
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Ventricular septal defect complicating anterior acute myocardial infarction : A Case of transcatheter closure.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38262253
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00153-1
Lamine H
Farhati A
Bouzidi H
Saidane S
Zairi I
Mzoughi K
Kraeim S
10.1016/j.ancard.2023.101718
AbstractText Label INTRODUCTION Post-infarction ventricular septal defect (PIVSD) is one of the most serious mechanical complications of acute myocardial infarction (AMI). Over the last decade, percutaneous closure is increasingly undertaken, with results similar to cardiac surgery. We present a case of ST-elevated anterior AMI, complicated by apical PIVSD successfully treated with transcatheter closure. /AbstractText AbstractText Label CASE REPORT An 83-year-old man was hospitalized for chest pain occurred 18 hours before, during the night time. He was an active smoker. Clinical examination revealed normal heart sounds and pulmonary bibasilar crackles. ST-segment elevation with deep T waves inversion in anterior leads were detected on the electrocardiogram. A mildly-reduced ejection fraction (40%) was found by transthoracic echocardiogram. The patient underwent emergency coronary angiography, which revealed a subocclusive stenosis of the mid left anterior descending artery with a TIMI 2 flow, treated by balloon angioplasty and drug-eluting stent. Four days after revascularization, the patient developed an acute deterioration with signs of decompensated heart failure and a new holosystolic murmur with large irradiation. Inotropic agents' administration was required to maintain a precarious hemodynamic condition. A bedside Echo revealed an apical VSD, measuring 15 10 mm, with left-to-right shunting, and pulmonary hypertension. The patient was scheduled for transcatheter PIVSD closure. The procedure was performed under fluoroscopic guide. Two vascular access sites were placed, femoral arterial and right internal jugular vein. Through the right internal jugular vein, a 24-mm Amplatzer atrial septal occluder on a 9 French Amplatzer TREVISIO intravascular delivery system was advanced via right ventricle into the PIVSD. Contrast fluoroscopy was used to assess apposition and the degree of shunt reduction before release. Echocardiographic evaluation performed 48 hours later confirmed a correct apposition of the device with insignificant residual shunt. At 6 months follow-up, he was asymptomatic, with unchanged prosthetic findings. /AbstractText AbstractText Label CONCLUSION Percutaneous closure has been emerged as a valid cost-effective alternative to surgery and should be advised. However, debate remains on the optimal preprocedural optimization, timing of repair and modality of treatment. /AbstractText
2
101718
73
communication interventriculaire; fermeture percutanée; infarctus du myocarde; myocardial infarction; percutaneous closure; ventricular septal defect
22
Avril
S0003-3928(23)00153-1
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
Mâle
humains
sujet âgé de 80 ans ou plus
résultat thérapeutique
endoprothèses à élution de substances
cathétérisme cardiaque
infarctus du myocarde
procédures de chirurgie cardiaque
dispositif d'occlusion septale
infarctus du myocarde antérieur
communications interventriculaires
communications interventriculaires
communications interventriculaires

---
Cas clinique : cas rare d'un faux anévrisme spontané de l'artère fémorale superficielle révélant une maladie de Behçet chez un jeune patient.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38262254
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00142-7
Kejiou H
Rizziki A
Ouhmich M
Benzirare A
Mahi OE
10.1016/j.ancard.2023.101707
Behçet's disease is a chronic inflammatory vascular disorder that can affect arteries and veins of various sizes. Arterial involvement, which plays a significant prognostic role, requires a treatment approach involving corticosteroids, immunosuppressants, and potentially surgical or endovascular procedures. This article presents the case of a young man diagnosed with Behçet's disease, manifested by a spontaneous pseudoaneurysm in the superficial femoral artery. The patient underwent surgical intervention to remove the pseudoaneurysm and restore circulation using a venous graft. This case underscores the importance of considering Behçet's disease in vascular manifestations.
2
101707
73
artère fémorale superficielle; behçet's disease; faux anévrisme; griffon veineuse; maladie de behçet; pseudoaneurysm; superficial femoral artery; venous graft
22
Avril
S0003-3928(23)00142-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
Mâle
humains
faux anévrisme
faux anévrisme
faux anévrisme
maladie de Behçet
maladie de Behçet
artère fémorale
pronostic
procédures endovasculaires

---
Une cause rare de syndrome coronarien aigu : l'embolie paradoxale.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38262255
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00156-7
Boussaadani BE
Mayoussi S
Zergoune N
Hara L
Amine EC
Raissouni Z
10.1016/j.ancard.2023.101721
Coronary artery embolism is an uncommon cause of myocardial infarction (MI). Among several etiologies of coronary embolism, we mention a very rare cause which is the paradoxical embolism via patent foramen ovale (PFO). It interests generally youngest people without cardiac risk factors. We report three cases who presented ST-elevation MI (STEMI) due to paradoxical embolism with high risk PFO that can justify embolic infarction. The aim of this article is to define the high risk PFO, to establish causal link between PFO and embolic events and to guide therapeutic management.
2
101721
73
coronary artery embolism; embolie de l'artère coronaire; embolie paradoxale; fop et événements emboliques; pfo and embolic events; paradoxical embolism
22
Avril
S0003-3928(23)00156-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
humains
embolie paradoxale
syndrome coronarien aigu
foramen ovale perméable
embolie
infarctus du myocarde

---
Association d’un myxome de l’oreillette gauche et d’un rétrécissement mitral : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38266406
https://linkinghub.elsevier.com/retrieve/pii/S0003-3928(23)00154-3
Bennani G
Atlas I
Zahri S
Haboub M
Drighil A
Habbal R
10.1016/j.ancard.2023.101719
Atrial myxoma is a rare and benign clinical entity. It remains common in women and mainly affects the left atrium. Its clinical picture is polymorphic. We report the case of a 53-year-old woman who consulted for dyspnea with cardiac failure's picture. The diagnosis of myxoma of the left atrium was made on echocardiography which also objectified the existence of mitral stenosis. The patient underwent surgical excision and mitral valve replacement with good postoperative outcomes.
2
101719
73
cardiac failure; insuffisance cardiaque; left atrium; mitral stenosis; myxoma; myxome; oreillette gauche; sténose mitrale
23
Avril
S0003-3928(23)00154-3
publication avant impression
Accès restreint
résumé en anglais
article de périodique
présentations de cas
humains
Femelle
adulte d'âge moyen
sténose mitrale
sténose mitrale
sténose mitrale
atrium du coeur
atrium du coeur
échocardiographie
tumeurs du coeur
tumeurs du coeur
tumeurs du coeur
myxome
myxome

---
Facteurs de risque de lésions malpighiennes intra-épithéliale de haut grade ou de cancer du col de l’utérus en cas de Maladie Inflammatoire Chronique de l’Intestin.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38266774
Dujardin C
Balcaen T
Vanoost A
Chatelain D
Gondry J
Fumery M
Foulon A
10.1016/j.gofs.2024.01.008
AbstractText Label INTRODUCTION Chronic inflammatory bowel disease (IBD) is thought to increase the risk of high-grade histological intraepithelial lesions (HGIL) and cervical cancer. The risk factors for developing these lesions are poorly understood. /AbstractText AbstractText Label MATERIALS AND METHODS This is a single-center retrospective case-control study including IBD patients followed at our University Hospital Center from 2011 to 2021 who presented with HGIL or cervical cancer. Four controls were case-matched according to IBD type, age, active smoking and multiparity. /AbstractText AbstractText Label RESULTS Eighteen cases and 72 controls were included. We found no significant differences between the 2 groups with regard to mean age at IBD diagnosis, mean duration of IBD, IBD location, history of IBD-related surgery or even association with another chronic inflammatory disease. In our study, the use of immunosuppressants/biotherapies in these patients (50% (9/18) for cases vs. 56% (40/72) for controls; p 0.9) was not a risk factor for IGRA or cervical cancer. Similarly, neither the total duration of exposure to immunosuppressants/biotherapies (9, 9 8 years for cases vs. 6, 6 5.3 years for controls; p 0.1), nor combined therapies (11% (2/18) for cases vs. 6% (4/72) for controls; p 0.3), nor azathioprine or methotrexate use (22% (4/18) for cases vs. 11% (8/72) for controls; p 0.3) were found to be risk factors. /AbstractText AbstractText Label CONCLUSION In our study, we found no risk factors for patients with IBD to develop IGRA or cervical cancer. /AbstractText
22
Janvier
S2468-7189(24)00012-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Les pièges de l’analyse dichotomique d’une variable biologique continue: l’exemple de la taille maternelle et du pronostic de l’accouchement d’un enfant de plus de 4,0kg.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38266775
Boujenah J
Wahnich A
Korb D
10.1016/j.gofs.2024.01.009
22
Janvier
S2468-7189(24)00013-8
publication avant impression
Accès restreint
lettre

---
Suspicion d’anomalie constitutionnelle au diagnostic de leucémie chez l’enfant : mise au point du comité leucémies de la Société française des cancers de l’enfant.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38267311
https://linkinghub.elsevier.com/retrieve/pii/S0007-4551(24)00004-3
Strullu M
Cousin E
de Montgolfier S
Fenwarth L
Gachard N
Arnoux I
Duployez N
Girard S
Guilmatre A
Lafage M
Loosveld M
Petit A
Perrin L
Vial Y
Saultier P
10.1016/j.bulcan.2023.11.011
The spectrum of childhood leukemia predisposition syndromes has grown significantly over last decades. These predisposition syndromes mainly involve CEBPA, ETV6, GATA2, IKZF1, PAX5, RUNX1, SAMD9/SAMD9L, TP53, RAS-MAPK pathway, DNA mismatch repair system genes, genes associated with Fanconi anemia, and trisomy 21. The clinico-biological features leading to the suspicion of a leukemia predisposition are highly heterogeneous and require varied exploration strategies. The study of the initial characteristics of childhood leukemias includes high-throughput sequencing techniques, which have increased the frequency of situations where a leukemia predisposing syndrome is suspected. Identification of a leukemia predisposition syndrome can have a major impact on the choice of chemotherapy, the indication for hematopoietic stem cell transplantation, and screening for associated malformations and pathologies. The diagnosis of a predisposition syndrome can also lead to the exploration of family members and genetic counseling. Diagnosis and management should be based on dedicated and multidisciplinary care networks.
3
291-309
111
childhood leukemia; leucémie de l’enfant; myelodysplastic syndrome; pre-leukemic state; predisposition; prédisposition; syndrome myélodysplasique; état préleucémique
23
Mars
S0007-4551(24)00004-3
publication avant impression
Accès restreint
résumé en anglais
guide de bonnes pratiques
Protéine SAMD9, humain
protéines et peptides de signalisation intracellulaire
enfant
humains
tumeurs
leucémies
leucémies
leucémies
famille
syndrome de Down
prédisposition génétique à une maladie

---
Réaction paradoxale tuberculeuse.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38267320
Azoulay LD
Houist AL
Feredj E
Vindrios W
Gallien S
10.1016/j.revmed.2024.01.008
Paradoxical tuberculosis reaction is defined as the aggravation of lesions present at diagnosis or the development of new lesions under anti-tuberculosis treatment, after exclusion of other alternate causes. It affects 5 to 30% of tuberculosis patients, with a variable prevalence depending on the site of infection and the clinical background. The diagnosis of paradoxical reaction is one of elimination, and requires having ruled out therapeutic failure, notably linked to poor compliance and/or to the presence of mycobacterial antibiotic resistance. The severity of paradoxical tuberculosis reaction lies in its neurological impairment. Despite its clinical importance, the mechanisms involved remain poorly understood and its management is not consensual. Corticosteroids are the cornerstone in the medical management. The role of anti-TNF agents, currently proposed in cases of corticodependence or corticoresistance, remains to be properly defined.
anti-tnf; corticosteroid; corticoïdes; granulomatose; granulomatosis; immune reconstitution inflammatory syndrome; paradoxical reaction; réaction paradoxale; syndrome inflammatoire de reconstitution immune; tuberculose; tuberculosis
23
Janvier
S0248-8663(24)00028-6
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature

---
Soins palliatifs : il est temps de clarifier le champ lexical.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38267321
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00029-8
Robert R
Goldberg M
10.1016/j.revmed.2024.01.009
2
61-64
45
end-of-life; fin de vie; limitation arrêt thérapeutique; palliative care; quality of life; qualité de vie; semantic; soins palliatifs; sémantique; withholding withdrawing life support
23
Février
S0248-8663(24)00029-8
publication avant impression
Accès restreint
article de périodique
humains
soins palliatifs
soins terminaux

---
Argumentaire « en faveur » de la greffe de cellules souches hématopoïétiques autologues dans la sclérodermie systémique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38267322
https://linkinghub.elsevier.com/retrieve/pii/S0248-8663(24)00006-7
Pugnet G
10.1016/j.revmed.2024.01.003
Autologous haematopoietic stem cell transplantation for systemic scleroderma, developed over more than 25 years, has shown in three randomised controlled clinical trials a significant impact not only in event-free survival, overall survival, cutaneous and pulmonary involvement, but also in the quality of life of patients living with recent severe diffuse cutaneous systemic scleroderma, compared with IV cyclophosphamid despite a transplant-related mortality between 2.4 and 10%. No immunosuppressants or biologics have shown such an impact on mortality in this disease. The risk of relapse is estimated between 9 and 24%, two years after transplant. On the basis of these results, French and international guidelines now position autologous haematopoietic stem cell transplantation as a level 1A evidence-based therapeutic alternative in severe early and rapidly progressive systemic scleroderma.
2
104-108
45
autogreffe; autologous haematopoietic stem cell transplantation; cell therapy; sclérodermie systémique; systemic scleroderma; thérapie cellulaire
23
Février
S0248-8663(24)00006-7
publication avant impression
Accès restreint
résumé en anglais
article de périodique
cyclophosphamide
immunosuppresseurs
humains
qualité de vie
transplantation de cellules souches hématopoïétiques
cyclophosphamide
immunosuppresseurs
transplantation autologue
sclérodermie systémique

---
De la saignée à l’immunothérapie.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268346
Lermen P
10.53738/REVMED.2024.20.858.113
858
113
20
24
Janvier
RMS0858-001
publication papier
Accès restreint
éditorial
humains
saignée
immunothérapie

---
Sécurité des patients : agissons ensemble pour une prise en charge sûre et efficace.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268348
https://doi.org/10.53738/REVMED.2024.20.858.115
Bonnabry P
10.53738/REVMED.2024.20.858.115
858
115-117
20
24
Janvier
RMS0858-003
publication papier
Accès restreint
article de périodique

---
Plaies chroniques, un potentiel défi quotidien pour le praticien.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268350
https://doi.org/10.53738/REVMED.2024.20.858.120
Vuagnat H
10.53738/REVMED.2024.20.858.120
858
120-121
20
24
Janvier
RMS0858-005
publication papier
Accès restreint
article de périodique

---
Mise au point du traitement médicamenteux dans l’insuffisance cardiaque.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268351
https://doi.org/10.53738/REVMED.2024.20.858.122
Alexe R
10.53738/REVMED.2024.20.858.122
858
122-124
20
24
Janvier
RMS0858-006
publication papier
Accès restreint
article de périodique
humains
défaillance cardiaque
défaillance cardiaque

---
Transition de genre : prise en charge par le généraliste.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268352
https://doi.org/10.53738/REVMED.2024.20.858.125
Dominicé Dao M
Bertholet L
Ritz C
Merglen A
10.53738/REVMED.2024.20.858.125
858
125-126
20
24
Janvier
RMS0858-007
publication papier
Accès restreint
article de périodique
humains
médecins généralistes

---
Polymédication et personne âgée.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268353
Graf C
10.53738/REVMED.2024.20.858.127
858
127-129
20
24
Janvier
RMS0858-008
publication papier
Accès restreint
article de périodique
sujet âgé
humains
polypharmacie

---
Traitement de la douleur et maniement des opiacés.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268354
Pautex S
10.53738/REVMED.2024.20.858.130
858
130-131
20
24
Janvier
RMS0858-009
publication papier
Accès restreint
article de périodique
alcaloïdes opiacés
humains
gestion de la douleur

---
Polyarthrite rhumatoïde.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268355
Lauper K
10.53738/REVMED.2024.20.858.132
858
132-134
20
24
Janvier
RMS0858-010
publication papier
Accès restreint
article de périodique
humains
polyarthrite rhumatoïde

---
Le défi de la renaissance psychédélique est la délimitation de l’usage thérapeutique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268356
Zullino D
10.53738/REVMED.2024.20.858.135
858
135-136
20
24
Janvier
RMS0858-011
publication papier
Accès restreint
article de périodique
hallucinogènes
humains

---
Antalgie intégrative : pourquoi et comment ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268357
Berna C
10.53738/REVMED.2024.20.858.137
858
137-138
20
24
Janvier
RMS0858-012
publication papier
Accès restreint
article de périodique
humains
analgésie
gestion de la douleur
douleur

---
Utilisation intelligente des somnifères.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268358
Haba-Rubio J
10.53738/REVMED.2024.20.858.139
858
139-140
20
24
Janvier
RMS0858-013
publication papier
Accès restreint
article de périodique
humains

---
Diagnostic et traitement de la tuberculose latente ou active.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268359
https://doi.org/10.53738/REVMED.2024.20.858.141
Janssens JP
10.53738/REVMED.2024.20.858.141
858
141-142
20
24
Janvier
RMS0858-014
publication papier
Accès restreint
article de périodique
humains
tuberculose
tuberculose
tuberculose
tuberculose latente
tuberculose latente

---
Désensibilisation aux aéroallergènes : indications et efficacité.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268360
https://doi.org/10.53738/REVMED.2024.20.858.143
Moi L
Borgeat A
10.53738/REVMED.2024.20.858.143
858
143-144
20
24
Janvier
RMS0858-015
publication papier
Accès restreint
article de périodique

---
Firstline : l’univers de la bonne utilisation des antibiotiques à portée de main.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268367
Bosetti D
10.53738/REVMED.2024.20.858.159
858
159-160
20
24
Janvier
RMS0858-022
publication papier
Accès restreint
article de périodique
antibactériens
humains

---
Nouveautés thérapeutiques dans la gestion des dysthyroïdies.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268368
https://doi.org/10.53738/REVMED.2024.20.858.161
Marino L
10.53738/REVMED.2024.20.858.161
858
161-162
20
24
Janvier
RMS0858-023
publication papier
Accès restreint
article de périodique

---
Traitements de la sclérose en plaques en 2024.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268369
https://doi.org/10.53738/REVMED.2024.20.858.163
Pot C
10.53738/REVMED.2024.20.858.163
858
163-165
20
24
Janvier
RMS0858-024
publication papier
Accès restreint
article de périodique
humains
sclérose en plaques
sclérose en plaques

---
Prévention cardiovasculaire : utile chez les personnes de plus de 70 ans ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268370
Rodondi N
10.53738/REVMED.2024.20.858.166
858
166
20
24
Janvier
RMS0858-025
publication papier
Accès restreint
article de périodique
humains
coeur
viscères

---
Hypnose médicale : mythes et réalités.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268371
Renold C
Berner A
Coen M
10.53738/REVMED.2024.20.858.167
858
167-169
20
24
Janvier
RMS0858-026
publication papier
Accès restreint
article de périodique
humains
hypnose

---
Grossesse et prescription en médecine de premier recours.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268372
Ditisheim A
10.53738/REVMED.2024.20.858.170
858
170-171
20
24
Janvier
RMS0858-027
publication papier
Accès restreint
article de périodique
Femelle
grossesse
humains
ordonnances
soins de santé primaires

---
Éthique médicale pour le praticien.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268373
Wolff H
10.53738/REVMED.2024.20.858.172
858
172-173
20
24
Janvier
RMS0858-028
publication papier
Accès restreint
article de périodique
humains
Déontologie médicale

---
Maladies inflammatoires chroniques de l’intestin chez les personnes âgées.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268377
Michetti P
10.53738/REVMED.2024.20.858.180
858
180-181
20
24
Janvier
RMS0858-032
publication papier
Accès restreint
article de périodique
sujet âgé
humains
maladies inflammatoires intestinales
intestins

---
Trouble anxieux et/ou dépressif résistant : que faire ?
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268378
Richard-Lepouriel H
Cordera P
10.53738/REVMED.2024.20.858.182
858
182-184
20
24
Janvier
RMS0858-033
publication papier
Accès restreint
article de périodique
humains
anxiété
troubles anxieux
trouble dépressif

---
Intermed : un modèle de soutien infirmier intégré en médecine de premier recours.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38268380
Walger O
Bramaud Du Boucheron A
Haberey-Knuessi V
Pedrotti M
Giovannini M
10.53738/REVMED.2024.20.858.187
Intermed, a primary care support nurse (PCN) model, was piloted from 2014 to 2021 in a general practice in La Chaux-de-Fonds. In collaboration with the physician and medical assistant, the PCN supports a proactive Chronic Care Model organization, and focuses specifically on patients in complex chronic situations. Integrated into the medical center, the PCN benefits from a close relationship with the physician. Her services, without apparent additional cost, often clarify the functioning of the network around the patients while allowing the latter to regain control over their care. However, her independent status makes her activity economically unviable within the framework of the LAMal and would require a mode of salaried employment which remains to be invented.Intermed, modèle de soins intégrant une infirmière de soutien en soins de premier recours (ISP), a été expérimenté de 2014 à 2021 dans un centre de médecine générale à La Chaux-de-Fonds. En collaboration avec le médecin et l’assistante médicale, l’ISP soutient une organisation proactive de type Chronic Care Model et se centre plus particulièrement sur les patients en situation chronique complexe. Intégrée dans le centre médical, l’ISP bénéficie d’une relation de proximité forte avec le médecin qui en fait un atout important. Si les prestations de l’ISP, sans surcoût apparent, clarifient souvent le fonctionnement du réseau autour des patients tout en permettant à ces derniers de reprendre un contrôle sur leurs soins, son statut d’indépendante rend son activité économiquement peu viable dans le cadre de la LAMal et nécessiterait un mode de salariat qui reste à inventer.
858
187-191
20
24
Janvier
RMS0858-035
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
Femelle
médecine générale
emploi
médecine de famille
hôpitaux
soins de santé primaires

---
L’Union des gérontopôles de France : une dynamique nationale de mobilisations régionales pour réussir le défi de la longévité.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269552
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1141
Annweiler C
Tenenbaum F
Hanon O
Charras K
Berrut G
10.1684/pnv.2023.1141
4
401-402
21
01
Décembre
pnv.2023.1141
publication papier
Accès restreint
article de périodique
humains
longévité
France

---
Maladie de Crohn du sujet âgé : Particularités cliniques et thérapeutiques.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269553
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1129
Elloumi H
Dabbebi H
10.1684/pnv.2023.1129
Crohn's disease (CD) is a pathology that typically affects young people. With the aging of the population, there is an increase of its incidence in the elderly. Several studies have compared the clinical and therapeutic features of the CD in the elderly and young patients with discordant results. The objective of this work was to identify the clinical and therapeutic characteristics of elderly onset CD. The clinical presentation of CD in the elderly has some peculiarities. It seems that the disease has a less severe profile. The ileal and colic locations as well as the inflammatory phenotype are the most frequent. The treatment of elderly patients poses a real challenge to the clinician because of the field particularity and the lack of large-scale data in the literature. The frequency of comorbidities and polymedications is at the origin of the lower prescription of immunomodulators and biotherapies and the frequency of postoperative complications and immunosuppressive treatments.
4
403-409
21
crohn’s disease; elderly; treatment
01
Décembre
pnv.2023.1129
publication papier
Accès restreint
résumé en anglais
article de périodique
sujet âgé
humains
adolescent
maladie de Crohn
maladie de Crohn
vieillissement
phénotype
complications postopératoires

---
Vaccination chez la personne âgée en Afrique subsaharienne : pertinence et modèle de calendrier.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269554
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1113
Ba M
Sall A
Djajhete R
Ba D
Coume M
10.1684/pnv.2023.1113
According to the World Health Organisation (WHO), recent decades have seen a major increase in the number of elderly people in Africa. Persistent infectious diseases are responsible for high morbidity and mortality in this immuno-senescent population, making vaccination an effective preventive measure. In developed countries, vaccination programs are in place and regularly updated. In sub-Saharan Africa, however, vaccination is still reserved for children, and access for seniors remains limited by a number of factors. The aim of this study was to use a systematic review to demonstrate the relevance of vaccination in this field, and to propose an appropriate vaccination schedule. Ultimately, vaccines against influenza, pneumococcus (23-valent), herpes zoster, diphtheria, pertussis and tetanus should be systematically recommended. Others may be discussed, depending on the fragility of the patient's condition.
4
410-418
21
elderly; sub-saharan africa; vaccination
01
Décembre
pnv.2023.1113
publication papier
Accès restreint
résumé en anglais
article de périodique
sujet âgé
humains
vaccination
Afrique subsaharienne

---
Évaluation du suivi ophtalmologique des patients de plus de 65 ans en médecine générale.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269555
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1115
Burel C
Chapelet G
Berrut G
Weber M
Ducloyer JB
10.1684/pnv.2023.1115
Visual disorders are often under-diagnosed and under-treated in older patients. The main objective was to evaluate the percentage of patients having an ophthalmological follow-up corresponding to the recommendations of the Syndicat national des ophtalmologistes de France (SNOF). This prospective observational multicentre study included all patients aged 65 years or older presenting to their general practitioner in two medical practices from May to October 2021. Of the 113 patients included, 86 (76,1 %) had adequate ophthalmological follow-up, 14 consulted an ophthalmologist, and a therapeutic decision was made for nine patients. Follow-up of patients was generally as recommended. Screening for visual disorders for patients with no recent follow-up was beneficial. This screening must be integrated into a global approach, as the Integrated Care for Older People (ICOPE) of the World Health Organization (WHO), in order to be more relevant and effective.
4
419-426
21
aged; general practitioners; vision screening; visual disorders
01
Décembre
pnv.2023.1115
publication papier
Accès restreint
résumé en anglais
article de périodique
étude d'observation
étude multicentrique
humains
sujet âgé
études de suivi
études prospectives
France
troubles de la vision
soins de santé primaires

---
Utilisation de la mélatonine chez les patients âgés hospitalisés en gériatrie en France : enquête auprès des pharmaciens hospitaliers.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269556
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1130
Duquenne C
Menard L
Dautricourt S
Mouchoux C
Novais T
10.1684/pnv.2023.1130
In recent years, melatonin has been increasingly used in hospital settings for the treatment of sleep disorders in older patients, despite many barriers: restriction by ANSM, non-approval to healthcare facility use, and non-reimbursement. In order to describe the use of melatonin in older hospitalized patients, a survey was conducted between February and May 2022, with hospital pharmacists working in geriatric care units in France. Overall, 35 interviews were conducted with hospital pharmacists: 30 dispensed melatonin, with marketed prolonged-release melatonin medications (n 30), and/or with immediate-release magistral or hospital preparations (n 11). The conducted survey highlighted the criteria for using the different forms of melatonin, but also the disparities in terms of supply and management within the different establishments. Given the increasing use of melatonin in hospital settings and in order to guarantee the same accessibility to hospital teams and to patients on discharge from the hospital, a reassessment by the authorities of the melatonin-based medication status seems necessary in the light of the new available data.
4
427-436
21
geriatric; hospital; melatonin; sleep disorders; survey
01
Décembre
pnv.2023.1130
publication papier
Accès restreint
résumé en anglais
article de périodique
mélatonine
humains
sujet âgé
mélatonine
pharmaciens
France
hôpitaux
sortie du patient

---
Validation d’une méthode de détection des hospitalisations pour chute liées à un effet indésirable médicamenteux en service de gériatrie aiguë.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269557
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1132
Vaesken C
Boulouard VL
Fedrizzi S
Abidi H
Richard H
Muzard A
Descatoire P
Villain C
Meurant A
10.1684/pnv.2023.1132
Fall is one of the five main causes of drug-related hospital admissions (DRA) in France. A standardized chart review method, to identify DRA adapted to elderly patients, has recently been developed by Thevelin et al. Our first aim was to assess the reliability of this method for detecting DRA for falls in elderly subjects. Our second aim was to assess the feasibility of this method and to evaluate its reliability for assessing causality, the contribution of DRA to hospitalization, and the avoidability of DRAs in elderly patients hospitalized for a medication-related fall. A retrospective observational study was conducted on 16 patient cases admitted to the hospital for falls in May 2022, in the geriatric department of a French university hospital. Six healthcare professionals (pharmacists, pharmacologists, and geriatricians) assessed a method for detecting DRA individually and then in multidisciplinary pairs of raters. Inter-rater agreement (individually and in pairs) was assessed for DRA detection, causality, avoidability, and contribution of the DRA to hospitalization. A κ 0,4 was considered a satisfactory threshold for agreement. The mean age was 86 years. When the assessment was done individually, detection of DRA-related hospitalizations (κ 0,46; p ,001), and DRA contribution to hospitalization (κ 0,50; p ,001) were moderately concordant. The causality assessment (κ 0,09; p 0,24) did not agree, and the avoidability assessment (κ 0,63; p ,001) agreed substantially. When the evaluation was done in pairs, detection of DRA-related hospitalizations (κ 0,47; p ,001) was moderately concordant between pairs. Avoidability assessment (κ 0,79; p ,001) concurred substantially. The assessment of causality (κ 0,29; p 0,01) and DRA contribution to hospitalization (κ 0,38; p .001) agreed fairly well. This study validated, individually and in pairs, the reliability of the method to identify DRA in the context of falls. This method will be of great use in research and epidemiological studies.
4
437-446
21
adverse drug event; elderly; fall; hospitalization; iatrogeny
01
Décembre
pnv.2023.1132
publication papier
Accès restreint
résumé en anglais
article de périodique
étude d'observation
sujet âgé
humains
sujet âgé de 80 ans ou plus
chutes accidentelles
reproductibilité des résultats
hospitalisation
effets secondaires indésirables des médicaments
hôpitaux universitaires

---
Prévention de la maltraitance en milieu hospitalier gériatrique : évaluation des pratiques professionnelles et réflexion autour des situations à risque.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269558
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1131
Roth R
Rigaud AS
Durig F
Chah-Walikian A
Kermanac'h L
Piccoli M
Hernandorena I
10.1684/pnv.2023.1131
Elder abuse and neglect in institutions is frequent, but is still not studied enough. This study aims to better understand the risks of elder abuse, through daily experiences of health professionals. This is a monocentric, qualitative study, with semi-structured interviews of health professionals working in a geriatric hospital. Geriatrics is a specialty at risk of abuse and neglect. There is a real taboo around this issue. The difficulty for its reporting is multifactorial (tolerance, trivialization of abusive behaviors, isolation, and apprehension of caregivers...). The lack of human, material, and educational resources provided by health institutions does not enable professionals, whoever they may be, to care for patients humanely. The guidance and support of caregivers (training, increased team cohesion, and dedicated time for multidisciplinary reflection) are aimed at improving patient care and quality of care. All health professionals are concerned with elder abuse and neglect. It is necessary to break the taboo around mistreatment, to learn to talk about it among colleagues, and to recognize and evaluate oneself in order to change, evolve, and train others to treat patients the best way possible. Health professionals have to train and learn about the specificities of geriatrics early, repetitively, and continuously during their training. Health professionals must be able to work in a stable environment, with a supportive management. Their work must be valued in a sustainable way. Better working conditions should enable a more caring and compassionate approach by healthcare professionals toward their patients.
4
447-455
21
caregivers; elder abuse; geriatric; health professionals; healthcare; institution; neglect
01
Décembre
pnv.2023.1131
publication papier
Accès restreint
résumé en anglais
article de périodique
sujet âgé
humains
Maltraitance des personnes âgées
hospitalisation
personnel de santé
apprentissage
gériatrie

---
Regards croisés sur la télémédecine en Ehpad : enquête auprès des professionnels impliqués dans la mise en place des téléconsultations dans les Ehpad du territoire rennais.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269559
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1112
Cady L
Costes M
Andres E
Dillinger F
Somme D
10.1684/pnv.2023.1112
The practice of telemedicine in nursing homes is a solution to improve the quality of care for residents. Its application also seems to be beneficial for the professionals involved, but it faces obstacles. The objective of this study is to explore the effects of the implementation of teleconsultations in nursing homes on the professional practices of the stakeholders involved. A qualitative focus group study was conducted with professionals involved in the implementation of teleconsultations. The data was analyzed using an inductive approach similar to grounded theory. The 18 participants included in the study were unanimous and consensual about the benefits of telemedicine. They observed changes in work relationships, particularly the key role of caregivers in coordinating care. However, they feared a deterioration in doctor-patient relationships. The practice of telemedicine was considered time-consuming, which could hinder its dissemination. No general practitioner participated in this study, showing they had reservations about the practice. The Covid-19 pandemic had an impact on the development of teleconsultations within the institutions involved. Telemedicine is acclaimed by the nursing homes teams and the doctors required, particularly through the effects on training and the added value it can bring to their practice. Telemedicine also allows to provide care that is otherwise not available. However, the care process needs to be simplified. In addition, there are obstacles to the involvement of general practitioners, which should be studied in order to optimize the coordination of care for the residents of the nursing homes.
4
457-467
21
telemedecine; general practice; innovation; nursing home
01
Décembre
pnv.2023.1112
publication papier
Accès restreint
résumé en anglais
article de périodique
humains
consultation à distance
pandémies
télémédecine
maisons de repos
médecins généralistes

---
Éditorial.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269560
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1138
Derouesne C
10.1684/pnv.2023.1138
4
468
21
01
Décembre
pnv.2023.1138
publication papier
Accès restreint
article de périodique

---
Mémoire épisodique et maladie d’Alzheimer : évolution des théories et des outils d’évaluation clinique.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269561
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1139
Launay A
Taconnat L
Vanneste S
Baudouin A
10.1684/pnv.2023.1139
Alzheimer's disease is characterized by an impairment of episodic memory in the early stages of the disease. Neuropsychological evaluation is performed for diagnostic purposes and to personalize follow-up. However, although many tests have been developed over the last few decades, not all of them seem to be able to meet this dual challenge. Through a review of the evolution of the concept of episodic memory and of knowledge about the disease, we discuss how neuropsychological tools have adapted. We question the interests and limits of existing tools for patients with Alzheimer's disease. At the end of this review, we suggest the criteria to be taken into account in order to propose a more integrative evaluation, able to describe the difficulties encountered as close as possible to the lived experience.
4
469-476
21
alzheimer’s disease; episodic memory; neuropsychological assessment; self
01
Décembre
pnv.2023.1139
publication papier
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
humains
maladie d'Alzheimer
mémoire épisodique
Savoir
tests neuropsychologiques

---
Fonctionnement cognitif dans la schizophrénie : une perspective vie entière.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269562
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1142
Raffard S
10.1684/pnv.2023.1142
Cognitive disorders are now well known in schizophrenia, but their evolution over time and particularly during aging remains poorly described. Current evidence indicates that cognitive deficits including attention, working memory, verbal learning and memory, and executive functions are present in 80% of individuals with schizophrenia, which, on average, are around two standard deviations below that in healthy controls. Cognitive impairments are important predictors of functioning in daily life, including quality of life, inability to live independently and unemployment. From a lifespan perspective, they are evident in infancy (18 months) and continually increase between infancy and adulthood (20 years) in full-scale IQ and most of cognitive domains, accelerating during the prodromal phase. Cognitive deficits are significant predictor of the psychotic transition, and they stabilize after the first psychotic episode until the age of fifty suggesting that cognitive deficits are mainly established before the prodromal phases of psychosis. Time course of cognitive impairments in elderly patients with schizophrenia appears to be more heterogeneous. While the data suggest that they are stable with advancing age, a subgroup of institutionalized older patients stands out for a significant cognitive decline, without it being possible to determine the causal direction of this association. The twofold increased risk of developing neurodegenerative dementia in this population, combined with institutionalization, could partly explain this cognitive decline in some patients. Long-term longitudinal studies in older adults with schizophrenia are clearly needed, particularly in France. Protective factors such as recovery-focused and psychosocial approaches need to be studied in this population, which has a 15-year shorter life expectancy than the general population.
4
477-485
21
aging; cognition; lifespan approach; schizophrenia
01
Décembre
pnv.2023.1142
publication papier
Accès restreint
résumé en anglais
article de périodique
sujet âgé
humains
schizophrénie
longévité
qualité de vie
cognition
Dysfonctionnement cognitif

---
Prescription inadaptée de psychotropes en unités de psychiatrie aiguë pour personnes âgées : une étude transversale multicentrique.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269564
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1137
Houix M
Humbert I
Mabileau G
Chapelet G
Sauvaget A
Gohier B
Armand-Branger S
Huon JF
D'Acremont F
Bulteau S
10.1684/pnv.2023.1137
Adverse drug reactions (ADRs) are a major public health issue, especially when it comes to the elderly. Potentially inappropriate prescribing (PIP) are one of the causes of ADRs in older people. A PIP can be defined as a prescription for which the benefit/risk ratio is unfavourable compared to other therapeutic alternatives. Psychotropic drugs are the second highest risk class for ADRs in the elderly. In order to reduce the prevalence of PIP, prescription assistance tools have been created. An inventory of PIP of psychotropic drugs in older patients hospitalized in psychiatry units was carried out in a French regional setting in 2019. A criteria grid was established based on 2 tools: STOPP/START criteria and Laroche's list adapted to French practice. This grid targeted each class of psychotropic drugs, drugs with a high anticholinergic burden and non-recommended combinations of psychotropic drugs. Three hundred forty-seven patients were included. A high prevalence of PPI was found for each class of psychotropic drugs. The highest prevalence of PPI was found among benzodiazepines (90.3%): long-term prescription, long half-life drugs, respiratory insufficiency or cognitive impairment condition. 56.5% of the subjects had a not-recommended combination of psychotropic drugs (prescription of drugs of the same pharmacotherapeutic class), 26% had a PIP of antipsychotics: prescription for insomnia, use of phenothiazine, 11.8% of drugs with anticholinergic properties and 7.4% of antidepressants: especially prescription of tricyclic drugs. These results obtained on a large population underline the interest of considering the specificities of prescriptions in the elderly. It shows both the interest and the limits of the current criteria defining the PIP in the context of a hospitalization in psychiatry for an acute disorder in elderly subjects.
4
496-505
21
drug use review; drugs; elderly; geriatrics; inappropriate prescribings; psychiatry; psychotropic
01
Décembre
pnv.2023.1137
publication papier
Accès restreint
résumé en anglais
article de périodique
psychoanaleptiques
neuroleptiques
protéines adaptatrices de la transduction du signal
antagonistes cholinergiques
sujet âgé
humains
psychoanaleptiques
France
effets secondaires indésirables des médicaments

---
Impact de la thérapie assistée par l’animal sur le bien être chez des patients présentant une maladie d’Alzheimer (étude ELIAUT).
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269565
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1134
Thirion E
Rouissi S
Dauphinot V
Garnier-Crussard A
Coste MH
Krolak-Salmon P
10.1684/pnv.2023.1134
The development of non-pharmacological interventions, including animal-assisted therapy (AAT), is an encouraging method for the care of people with Alzheimer's disease (AD). A single-center, randomized, single-blind, controlled intervention study was proposed to compare immediate well-being measured by a visual analog scale (EVIBE) as primary outcome between the intervention group (AAT combined with cognitive stimulation) and the control group (cognitive stimulation only) in AD patients. Secondary outcomes were explored, such as well-being after intervention (also with the EVIBE), cognitive performance (measured by Alzheimer's Disease Assessment Scale, cognitive part GRECO version), behavioral and psychological symptoms of dementia (with the Neuropsychiatric Inventory Behavioral Scale-Nursing Home Version), current depressive symptomatology (with the 30 items Geriatric Depression Scale [GDS 30]) and anxiety (by the State-Trait Anxiety Inventory). Forty-two patients were included, 22 in the intervention group and 20 in the control group. The mean age was 82.5 years and mean MMSE score 19.2 in the control group and 81.4 years and mean MMSE score 18.4 in the TAA group. The results show a significant effect of the intervention on well-being after four weeks (p 0.048), but no significant effect on cognitive functioning, behavioral and psychological symptoms of dementia. This study shows a small effect of TAA on well-being four weeks after the end of the intervention. The assessment of well-being by another measurement tool and the collection of observations made by the care team could be explored in future studies, which could require a larger sample and a longer follow-up.
4
506-516
21
alzheimer’s disease; animal-assisted therapy; major neurocognitive disorder; well-being
01
Décembre
pnv.2023.1134
publication papier
Accès restreint
résumé en anglais
article de périodique
essai contrôlé randomisé
animaux
humains
sujet âgé
sujet âgé de 80 ans ou plus
thérapie assistée par l'animal
maladie d'Alzheimer
méthode en simple aveugle
anxiété
cognition

---
Agenda.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38269566
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/pnv.2023.1140
10.1684/pnv.2023.1140
4
517-518
21
01
Décembre
pnv.2023.1140
publication papier
Accès restreint
article de périodique

---
Mise en place du dépistage de l’infection congénitale à cytomégalovirus dans une maternité française de type 3.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38272182
https://linkinghub.elsevier.com/retrieve/pii/S2468-7189(24)00014-X
Mazeau PC
Hamon M
Ribot É
Hantz S
Alain S
10.1016/j.gofs.2024.01.010
AbstractText Label OBJECTIVES Congenital cytomegalovirus (CMV) infection is the most common congenital infection and the leading cause of infectious neurosensorial disability in newborns. We wanted to organize the management of women from the beginning of pregnancy allowing access to antenatal treatment with valaciclovir, recognized since 2020 as limiting materno-fetal transmission. To this end, we set up and evaluated the interest of systematic screening for CMV infection in our maternity. We wanted to organize care for women from the very start of pregnancy. /AbstractText AbstractText Label METHODS retrospective and comparative descriptive study carried out at the CHRU de Limoges from July 2017 to December 2019 (targeted screening), then from January 2020 to June 2022, during which period we implemented systematized screening by iterative serologies at the 3rd, 6th, 8th months and before delivery. Our main evaluation criteria were the seroprevalence of CMV infection and the rate of congenital infection. We then described our cases of infection (primary or secondary) during pregnancy. /AbstractText AbstractText Label RESULTS CMV seroprevalence in our pregnant women increased significantly from 52.7% (779/1478 women screened) to 58.4% (3852/6599 women screened) between the 2 study periods (p 0.04). We diagnosed 11 infections during the first part of the study vs. 27 during the second, with a significant increase in primary infections from 0.14% (9/6524 births) to 0.37% (24/6426 births) (p 0.008). Only 3 secondary infections were diagnosed during the second study period. The rate of congenital infections remained stable between the 2 study periods (6 children/6524 0.09% vs. 8 children/6426 0.12%; p 0.57). /AbstractText AbstractText Label CONCLUSION Our results confirmed the interest of screening for CMV infection, while modifying the screening strategy we had initiated. /AbstractText
congenital infection; cytomegalovirus; pregnancy; screening
23
Janvier
S2468-7189(24)00014-X
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Carcinome à cellules hautes et à polarité inversée du sein : à propos d’un cas.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38272722
https://linkinghub.elsevier.com/retrieve/pii/S0242-6498(24)00001-4
Hmidi A
Houcine Y
Kamoun S
Ilhem B
Goucha A
Driss M
10.1016/j.annpat.2024.01.001
Reverse polarity high-cell carcinoma of the breast, formerly known as reverse polarity solid papillary carcinoma, is a rare entity recently introduced into the latest edition of the WHO classification of breast tumors. Its phenotype is triple-negative, and its diagnosis difficult. Although few cases have been reported in the literature, knowledge of this breast tumor is essential to distinguish it from other triple-negative carcinomas, which have a poorer prognosis. We report a case of high-cell, inverted-polarity carcinoma of the breast in a 43-year-old female patient with no history of breast neoplasia and no palpable mass on clinical examination. The tumour was discovered following a screening echomammogram, which revealed a lesion classified ACR 4b. A microbiopsy of this lesion concluded that it was a papillary proliferation that should be removed. A lumpectomy was performed. Histopathological and immunohistochemical studies of the surgical specimen confirmed the diagnosis of high-cell, reverse-polarity carcinoma expressing calretinin and IDH1. Given the rarity of this entity, there is no standard treatment. In our case, a mastectomy without lymph node curage was performed. The extension work-up was negative and the patient received no adjuvant treatment. After 12 months, the patient is in complete remission. In this case report, we describe the histopathological, immunohistochemical and molecular features of this rare entity.
breast cancer; cancer du sein; carcinome à cellules hautes et à polarité inversée; case report; high-cell and reverse polarity carcinoma; lésion papillaire; papillary lesion; rapport de cas; rare
24
Janvier
S0242-6498(24)00001-4
publication avant impression
Accès restreint
résumé en anglais
article de périodique

---
Complications pulmonaires de la granulomatose septique chronique.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38272769
http://www.em-consulte.com/retrieve/pii/S0761-8425(24)00002-0
https://linkinghub.elsevier.com/retrieve/pii/S0761-8425(24)00002-0
Salvator H
Mahlaoui N
Suarez F
Marcais A
Longchampt E
Tcherakian C
Givel C
Chabrol A
Caradec E
Lortholary O
Lanternier F
Goyard C
Couderc LJ
Catherinot E
10.1016/j.rmr.2024.01.002
Chronic Granulomatosis Disease (CGD) is an inherited immune deficiency due to a mutation in the genes coding for the subunits of the NADPH oxidase enzyme that affects the oxidative capacity of phagocytic cells. It is characterized by increased susceptibility to bacterial and fungal infections, particularly Aspergillus, as well as complications associated with hyperinflammation and granulomatous tissue infiltration. There exist two types of frequently encountered pulmonary manifestations: (1) due to their being initially pauci-symptomatic, possibly life-threatening infectious complications are often discovered at a late stage. Though their incidence has decreased through systematic anti-bacterial and anti-fungal prophylaxis, they remain a major cause of morbidity and mortality; (2) inflammatory complications consist in persistent granulomatous mass or interstitial pneumoniae, eventually requiring immunosuppressive treatment. Pulmonary complications recurring since infancy generate parenchymal and bronchial sequelae that impact functional prognosis. Hematopoietic stem cell allograft is a curative treatment; it is arguably life-sustaining and may limit the morbidity of the disease. As a result of improved pediatric management, life expectancy has increased dramatically. That said, new challenges have appeared with regard to adults: difficulties of compliance, increased inflammatory manifestations, acquired resistance to anti-infectious therapies. These different developments underscore the importance of the transition period and the need for multidisciplinary management.
2
156-170
41
aspergillus; chronic granulomatous disease; déficit immunitaire héréditaire; granulomatose septique chronique; inflammation; nadph oxidase; nadph oxydase; primary immunodeficiency
24
Février
S0761-8425(24)00002-0
publication avant impression
Accès restreint
résumé en anglais
article de périodique
revue de la littérature
NADPH oxidase
adulte
humains
enfant
granulomatose septique chronique
granulomatose septique chronique
granulomatose septique chronique
NADPH oxidase
NADPH oxidase
bactéries
poumon
mutation

---
François Gros, secrétaire perpétuel de l’Académie des sciences.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38275107
https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.144
https://doi.org/10.5802/crbiol.144
Bach JF
10.5802/crbiol.144
François Gros was Permanent Secretary of the French Academy of Sciences from 1991 to 2000. His immense scientific knowledge, his tireless efforts to develop international relations, particularly with developing countries, and his exceptional personality have greatly contributed to the modernisation and influence of the Academy.François Gros a été secrétaire perpétuel de l’Académie des sciences de 1991 à 2000. Son immense culture scientifique, son activité incessante pour le développement des relations internationales en particulier vers les pays en développement, et sa personnalité exceptionnelle ont grandement contribué à la modernisation et au rayonnement de l’Académie.
S2
91-93
346
académie des sciences; françois gros; secrétaire perpétuel
29
Mars
publication avant impression
Accès restreint
résumé en anglais
article de périodique
académies et instituts
France
article historique

---
Caractéristiques et pronostic des insuffisances rénales aiguës dialysées au cours des vascularites à ANCA.
2024
http://www.ncbi.nlm.nih.gov/pubmed/38282439
http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ndt.2024.58
Siham A
Hafedh F
Jean-Jacques B
Pierre-Antoine M
10.1684/ndt.2024.58
Renal involvement in ANCA (Anti Neutrophil Cytoplasmic Antigen) vasculitis is common and is associated with increased mortality with a significant risk of progression to end-stage renal disease. The aim of this study is to investigate the epidemiological, clinicopathological, therapeutic and evolutionary characteristics of patients with ANCA vasculitis with acute renal injury, and to evaluate the impact of haemodialysis in the acute phase on mortality and renal recovery. Secondary objectives are to investigate other risk factors that impact on overall and renal survival. 31 patients were included ; the mean follow-up time was 30 months. The mean age was 68.52 years, and the sex ratio 0.72. All patients had acute renal failure, with histology revealing a mixed form in 45% of cases and a sclerotic form in 12.9% of cases. Pulmonary involvement was found in 58% of cases. 71% of patients had ANCA with anti-myeloperoxydase specificity, and 25.8% anti-proteinase 3 specificity. 32.2% of patients required haemodialysis, of which 60% were weaned. As initial treatment, 58.1% of patients received cyclophosphamide and 35.5% rituximab. The relapse rate was 6.5%. Infectious and cardiovascular complications affected more than half of the patients. The mortality rate was 19.35%. Comparing the two groups of patients dialysed in the acute phase and not dialysed, it appears that the overall and renal mortality was comparable. The progression to end-stage renal failure was higher in the dialysis patients. In a multivariate study, the presence of chronic kidney disease in the history and pulmonary involvement were associated with higher mortality.L’atteinte rénale au cours des vascularites à ANCA (anticorps anticytoplasmes des polynucléaires neutrophiles) est fréquente ; elle est associée à une surmortalité avec un risque important d’évolution vers l’insuffisance rénale terminale. L’objectif de ce travail est d’étudier les caractéristiques épidémiologiques, clinico-paracliniques, thérapeutiques et évolutives de patients atteints de vascularite à ANCA avec insuffisance rénale aiguë, et d’évaluer l’impact du recours à l’hémodialyse à la phase aiguë sur la mortalité et la récupération rénale. Les objectifs secondaires sont de rechercher d’autres facteurs de risque ayant un impact sur la survie globale et rénale. Trente et un patients ont été inclus, avec un délai moyen de suivi de 30 mois. L’âge moyen était de 68,5 ans, et le sex ratio de 0,72. Tous les patients avaient une insuffisance rénale aiguë, dont l’histologie a révélé une forme mixte dans 45 % des cas et une forme scléreuse dans 12,9 % des cas. Une atteinte pulmonaire était retrouvée dans 58 % des cas. Parmi les patients, 71 % (22) avaient des ANCA de spécificité anti-myélopéroxydase, contre 25,8 % (8) de spécificité anti-protéinase 3. Au total, 32,2 % des patients ont eu recours à l’hémodialyse, dont 60 % ont été sevrés. En traitement d’attaque, 58,1 % des patients ont reçu du cyclophosphamide et 35,5 % du rituximab. Le taux de rechutes était de 6,5 %. Les complications infectieuses et cardiovasculaires concernaient plus de la moitié des patients. Le taux de mortalité était de 19,35 %. En comparant les deux groupes des patients dialysés à la phase aiguë et non dialysés, il apparaît que la mortalité globale et rénale était comparable. L’évolution vers l’insuffisance rénale terminale était plus élevée chez les patients dialysés. En étude multivariée, la présence d’une insuffisance rénale chronique dans les antécédents et l’atteinte pulmonaire étaient associées à une surmortalité.
1
1-12
20
acute kidney injury; anca; hemodialyse; mortality; kidney survival; vascularitis
28
Février
publication avant impression
Accès restreint
article de périodique
Anticorps anti-cytoplasme des polynucléaires neutrophiles
humains
sujet âgé
dialyse rénale
Anticorps anti-cytoplasme des polynucléaires neutrophiles
Vascularites associées aux anticorps anti-cytoplasme des neutrophiles
études rétrospectives
défaillance rénale chronique
défaillance rénale chronique
pronostic
atteinte rénale aigüe
atteinte rénale aigüe
atteinte rénale aigüe

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Prévalence des hépatites virales B et C chez les hommes ayant des rapports sexuels avec d’autres hommes mobilisés pour une étude de démonstration de la prophylaxie préexposition au VIH à Cotonou, au Bénin.
2023
http://www.ncbi.nlm.nih.gov/pubmed/38282778
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10819840
https://www.panafrican-med-journal.com/content/article/46/79/full/
Béhanzin L
Diabaté S
Guédou FA
Matsétsé EG
Olodo M
Dossouvo A
Aza-Gnandji M
Akpaka A
Chagas E
Gangbo F
Zannou DM
Alary M
10.11604/pamj.2023.46.79.41013
AbstractText Label INTRODUCTION men who have sex with men (MSM) are disproportionately affected by hepatitis B virus (HBV) and hepatitis C virus (HCV) worldwide. In Benin, there are no data on MSM. The purpose of this study was to estimate HBV and HCV prevalence and HBV-associated factors in MSM who were HIV negative. /AbstractText AbstractText Label METHODS we conducted an analytical cross-sectional study. A two-degree random sampling was used to recruit 204 MSM. An immunochromatographic rapid test and enzyme immunoassays were used to detect HBV and HCV antigens/antibodies. Log-binomial regression was used to identify factors associated with HBV. /AbstractText AbstractText Label RESULTS HbsAg positivity, history of hepatitis B infection and hepatitis C prevalences were 37.7%, 8.8 %, and 0.9 %, respectively. HBsAg positivity and history of hepatitis B were more prevalent in MSM aged 30 years compared to younger subjects: 16.7% versus 6.4% (p 0.0001) and 66.7% versus 28.8% (p 0.0001), respectively. Sexual intercourse under the effect of drug or alcohol and living in couple were also associated with HBV. /AbstractText AbstractText Label CONCLUSION the prevalence of hepatitis C was low, but hepatitis B was common, especially among older MSM. Screening and vaccination against hepatitis B should be strengthened in this population. /AbstractText
79
46
benin; cotonou; men who have sex with men; associated factors; hepatitis b; hepatitis c; prevalence; sexually transmitted infections
PAMJ-46-79
publication électronique
Accès restreint
résumé en anglais
article de périodique
antigènes de surface du virus de l'hépatite B
anticorps de l'hépatite C
Mâle
humains
homosexualité masculine
prévalence
infections à VIH
infections à VIH
coït
études transversales
Bénin
Prophylaxie pré-exposition
hépatite B
hépatite B
hépatite B
hépatite C
hépatite C
hépatite C
virus de l'hépatite B
hepacivirus

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