NCIt definition : B-lymphocyte antigen CD19 (556 aa, 61 kDa) is encoded by the human CD19 gene. This
protein is involved in enhancing B-cell receptor-dependent signaling.;
NCIt note : When B-lymphocyte antigen CD19 complexes with the B-cell receptor, the threshold for
antigen receptor-dependent stimulation of B lymphocyte proliferation is decreased.
Additionally, CD19 functions as an adapter protein for Src family kinase amplification,
which is crucial for antigen receptor-induced signal transduction.;