NCIt definition : A preparation of autologous T-lymphocytes that are genetically engineered to express
a chimeric antigen receptor (CAR) specific for the tumor-associated antigen (TAA)
CD19, with potential immunostimulating and antineoplastic activities. Upon intravenous
administration, rapcabtagene autoleucel is directed to and induces selective toxicity
in CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface antigen
expressed in all B-cell lineage malignancies.;