NCIt definition : A preparation of autologous T-lymphocytes that have been genetically engineered to
express a chimeric antigen receptor (CAR) specific for the tumor-associated antigen
(TAA) CD19, with potential immunomodulating and antineoplastic activities. Upon administration,
autologous anti-CD19 CAR T-cells KITE-197 specifically recognize and kill tumor cells
expressing CD19. CD19 antigen is a B-cell specific cell surface antigen expressed
in all B-cell lineage malignancies.;