Preferred Label : Azercabtagene Zapreleucel;
NCIt synonyms : Allogeneic Anti-CD19-CAR T-lymphocytes PBCAR0191; Anti-CD19-CAR Allogeneic T-cells PBCAR0191; Allogeneic Anti-CD19-CAR T-cells PBCAR0191;
NCIt definition : A preparation of allogeneic, off-the-shelf, T-lymphocytes that have been genetically
modified using a proprietary synthetic nuclease-based system to express a chimeric
antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD19 (cluster
of differentiation 19) with potential immunostimulating and antineoplastic activities.
Upon administration, azercabtagene zapreleucel specifically recognize and kill CD19-expressing
tumor cells. CD19 antigen is a B-cell specific cell surface antigen, which is expressed
in all B-cell lineage malignancies and normal B-cells.;
UNII : PFZ3AP93TA;
Molecule name : PBCAR0191;
NCI Metathesaurus CUI : CL938005;
Origin ID : C158558;
UMLS CUI : C4764273;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
- has_target
