MAP2K2 wt Allele

Preferred Label : MAP2K2 wt Allele;

NCIt synonyms : Mitogen-Activated Protein Kinase Kinase 2 wt Allele; MAPKK2; MEK2; MKK2; PRKMK2;

NCIt definition : Human MAP2K2 wild-type allele is located in the vicinity of 19p13.3 and is approximately 34 kb in length. This allele, which encodes dual specificity mitogen-activated protein kinase kinase 2 protein, is involved in both MAPK and toll-like receptor signaling pathways. Mutation of the gene is associated with cardiofaciocutaneous syndrome.;

GenBank Accession Number : L11285;

Details

Origin ID

C106607;

UMLS CUI

C3811164;

Automatic exact mappings (from CISMeF team)
- MAP kinase kinase 2 [MeSH Descriptor]
- MAP kinase kinase activity [GO term]
- Mitogen-activated protein kinase kinase 2 [OMIM gene]
- mitogen-activated protein kinase kinase 2 [ORDO Gene]
OMIM relation
- Mitogen-activated protein kinase kinase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19p13.3 [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- Anthrax Toxin Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Bladder Cancer Pathway [NCIt concept]
- Cadmium Induction Pathway [NCIt concept]
- Calpain-2 Cell Motility Pathway [NCIt concept]
- Cardiac Hypertrophy Pathway [NCIt concept]
- Cellular Anthrax Toxin Pathway [NCIt concept]
- Ceramide Signaling Pathway BioCarta [NCIt concept]
- Ceramide Signaling Pathway PID [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- G-Protein Signaling Pathway [NCIt concept]
- GPCR Signaling Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Growth Hormone Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- Human Cytomegalovirus Infection Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- MAP Kinase Activation Pathway [NCIt concept]
- MAP Kinase Downregulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Map Kinase Inactivation of SMRT Corepressor Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- Melanocyte Development Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Mucosal Healing Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Phospholipid Signaling Pathway [NCIt concept]
- Prion Disease Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- Ras Signaling Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- SRF Activation Pathway [NCIt concept]
- Splicing Regulation Pathway [NCIt concept]
- Sprouty Regulation of Tyrosine Kinase Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- TGF Beta Signaling Pathway BioCarta [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_plays_role_in_process
- Intracellular Transport [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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