" /> Phosphatidylinositol-4,5-Bisphosphate 3-Kinase - CISMeF





Preferred Label : Phosphatidylinositol-4,5-Bisphosphate 3-Kinase;

NCIt synonyms : PI3-Kinase; EC 2.7.1.153; PI 3 Kinase; 1-Phosphatidylinositol 3-Kinase; Type I Phosphatidylinositol Kinase; Type III Phosphoinositide 3-Kinase; Phosphatidylinositol-3-Kinase; Phosphatidylinositol 3-Kinase; Phosphatidylinositide 3-Kinase; Phosphatidylinositol 3 Kinase;

NCIt related terms : PI3K; PI3 kinase; phosphatidylinositol-3 kinase;

NCIt definition : An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. (from LocusLink);

Alternative definition : NCI-GLOSS: A type of enzyme that transmits signals in cells and that helps control cell growth. Some tumors have higher-than-normal levels of phosphatidylinositol-3 kinase.;

Codes from synonyms : CDR0000549424; CDR0000530323; CDR0000549422;

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Keyword's position in hierarchy(ies) : arborescence

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12/05/2024


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