PI3K/HDAC Inhibitor BEBT-908

Preferred Label : PI3K/HDAC Inhibitor BEBT-908;

NCIt related terms : BEBT-908;

NCIt definition : The hydrochloride salt form of the free base form of BEBT-908, an inhibitor of both phosphoinositide 3-kinase (PI3K) and histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon administration, PI3K/HDAC inhibitor BEBT-908 binds to and inhibits the activity and mediated signaling of both PI3K and HDAC. In addition, BEBT-908 may also inhibit other signaling pathways. This may prevent growth of PI3K and/or HDAC-expressing tumor cells.;

UNII : SM27EVR8ZU;

CAS number : 1646906-27-5;

Molecule name : CUDC-908; BEBT 908; CUDC 908; BEBT-908;

NCI Metathesaurus CUI : CL1921217;

Details

Origin ID

C202249;

UMLS CUI

C4549223;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BEBT-908 [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Histone Deacetylase [NCIt concept]
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase [NCIt concept]

Keyword's position in hierarchy(ies) :

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