Ifupinostat Hydrochloride

Preferred Label : Ifupinostat Hydrochloride;

NCIt synonyms : PI3K/HDAC Inhibitor BEBT-908; BEBT-908 Hydrochloride;

NCIt related terms : BEBT-908;

NCIt definition : The hydrochloride salt form of ifupinostat,, an inhibitor of both phosphoinositide 3-kinase (PI3K) and histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon administration, ifupinostat binds to and inhibits the activity and mediated signaling of both PI3K and HDAC. In addition, ifupinostat may also inhibit other signaling pathways. This may prevent growth of PI3K and/or HDAC-expressing tumor cells.;

UNII : SM27EVR8ZU;

CAS number : 1646906-27-5;

Molecule name : CUDC-908; BEBT 908; CUDC 908; BEBT-908;

NCI Metathesaurus CUI : CL1921217;

Details

Origin ID

C202249;

UMLS CUI

C4549223;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BEBT-908 [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Ifupinostat [NCIt concept]
has_target
- Histone Deacetylase [NCIt concept]
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase [NCIt concept]
is_salt_form_of
- Ifupinostat [NCIt concept]

Keyword's position in hierarchy(ies) :

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