NCIt definition : An inhibitor of both phosphoinositide 3-kinase (PI3K) and histone deacetylase (HDAC)
enzymes, with potential antineoplastic activity. Upon administration, ifupinostat
binds to and inhibits the activity and mediated signaling of both PI3K and HDAC. In
addition, ifupinostat may also inhibit other signaling pathways. This may prevent
growth of PI3K and/or HDAC-expressing tumor cells.;
Semantic type(s)