Wortmannin - CISMeF

Preferred Label : Wortmannin;

NCIt synonyms : (1S,6bR,9aS,11R,11bR)-11-(Acetyloxy)-1,6b,7,8,9a,10,11,11b-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]indeno[4,5-h]-2-benzopyran-3,6,9-trione; (1 Alpha,11 alpha)-11-(acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan- 3,7,17-trione;

NCIt related terms : 2-Oxaandrosta-5,8-dieno[6,5,4-bc]furan-3,7,17-trione, 11-(acetyloxy)-1-(methoxymethyl)-, (1.alpha.,11.alpha.)-;

NCIt definition : A potent fungal metabolite isolated from Penicillium wortmannin that selectively inhibits phosphatidylinositol 3-kinase and affects the signal transduction pathway. (NCI);

UNII : XVA4O219QW;

CAS number : 19545-26-7;

Molecule name : SL-2052;

NSC code : 627609; 221019;

ChEBI ID : CHEBI:52289;

Codes from synonyms : NSC0627609; 50408; NSC0221019;

Details

Origin ID

C1277;

UMLS CUI

C0078517;

Currated CISMeF NLP mapping
- Wortmannin [MeSH Descriptor]
- wortmannin [MeSH concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Wortmannin [MeSH Descriptor]
- wortmannin [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_target
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase [NCIt concept]

Keyword's position in hierarchy(ies) :

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