" /> Fimepinostat - CISMeF





Preferred Label : Fimepinostat;

NCIt definition : An orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, fimepinostat inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types. This may prevent growth of PI3K and/or HDAC-expressing tumor cells. CUDC-907 shows an increased inhibition of tumor cell growth and induction of apoptosis when compared to inhibitors that target either PI3K or HDAC.;

UNII : 3S9RX35S5X;

InChIKey : JOWXJLIFIIOYMS-UHFFFAOYSA-N;

CAS number : 1339928-25-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1339928-25-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : CUDC-907;

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Keyword's position in hierarchy(ies) : arborescence

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12/05/2024


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