phosphatidylinositol 3-Kinases

Preferred Label : phosphatidylinositol 3-Kinases;

MeSH definition : Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.;

MeSH synonym : pi 3-kinase; ptdins 3-kinase; pi-3k; pi-3 kinase; phosphoinositide 3-hydroxykinase; pi3-kinase; PtdIns 3-Kinases; PtdIns 3 kinases; PI3 kinases; kinases, PI3; Phosphatidylinositol-3-OH kinase; phosphatidylinositol 3 kinases; 3-Hydroxykinase, Phosphoinositide; Phosphoinositide 3 Hydroxykinase; PI 3 Kinase; Kinase, PI-3; Phosphoinositide 3 Kinases; Kinases, Phosphoinositide 3; PI3 Kinase; PtdIns 3 Kinase; Kinase, Phosphatidylinositol-3-OH; Phosphatidylinositol 3 OH Kinase;

CISMeF synonym : 3-kinase, vps34 phosphatidylinositol; pi 3k isotype p110 gamma; 3-kinase, pi; p110 gamma; ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase; 3-kinase, ptdins; 3-kinase, phosphatidylinositol; pi-3k isotype p110 gamma; gamma, p110; subunit, pi-3k alpha-p85; 3-kinase, 1-phosphatidylinositol; alpha p85 subunit, pi 3k; 3-Kinases, PtdIns;

Registry Number MeSH : EC 2.7.1.137; EC 2.7.1.-;

MeSH annotation : note specifics including PHOSPHATIDYLINOSITOL 3-KINASE are available;

Is substance : O;

Details

Origin ID

D019869;

UMLS CUI

C2936824;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
False automatic mappings
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase [NCIt concept]
Indexing information
- 1-(((3-(dimethylamino)propyl)(methyl)amino)methylene)-7,11-dihydroxy-4-(methoxymethyl)-4a,6a-dimethyl-2,10-dioxo-1,2,4,4a,5,6,6a,7,8,9,9a,10-dodecahydroindeno(4,5-h)isochromene-5-yl acetate [MeSH Supplementary Concept]
- 1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol [MeSH Supplementary Concept]
- 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine [MeSH Supplementary Concept]
- 2-(3-(2-(1-isopropyl-3-methyl-1H-1,2-4-triazol-5-yl)-5,6-dihydrobenzo(f)imidazo(1,2-d)(1,4)oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide [MeSH Supplementary Concept]
- 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one [MeSH Supplementary Concept]
- 2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one [MeSH Supplementary Concept]
- 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol [MeSH Supplementary Concept]
- 3-(2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol [MeSH Supplementary Concept]
- 4-(2-(dimethylamino)vinyl)-2-(3-hydroxyphenyl)-6-morpholinopyrimidine-5-carbonitrile [MeSH Supplementary Concept]
- 5-(2,2-difluorobenzo(1,3)dioxol-5-ylmethylene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-(5-(4-fluoro-2-hydroxyphenyl)furan-2-ylmethylene)thiazolidine-2,4-dione [MeSH Supplementary Concept]
- 5-quinoxalin-6-ylmethylenethiazolidine-2,4-dione [MeSH Supplementary Concept]
- Alpelisib [MeSH Supplementary Concept]
- ETP 45658 [MeSH Supplementary Concept]
- ETP-46321 [MeSH Supplementary Concept]
- GNE-293 [MeSH Supplementary Concept]
- GNE-317 [MeSH Supplementary Concept]
- IC 486068 [MeSH Supplementary Concept]
- IC 87114 [MeSH Supplementary Concept]
- KT 7692 [MeSH Supplementary Concept]
- LY 290042 [MeSH Supplementary Concept]
- N-(2-(dimethylamino)ethyl)-N-methyl-4-(((4-(4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H-pyrrolo(2,3-d)pyrimidin-2-yl)phenyl)carbamoyl)amino)benzamide [MeSH Supplementary Concept]
- PI 540 [MeSH Supplementary Concept]
- PI 620 [MeSH Supplementary Concept]
- PIK 75 [MeSH Supplementary Concept]
- PKI 402 [MeSH Supplementary Concept]
- Wortmannin [MeSH Descriptor]
- ZSTK474 [MeSH Supplementary Concept]
- duvelisib [MeSH Supplementary Concept]
- gedatolisib [MeSH Supplementary Concept]
- halenaquinone [MeSH Supplementary Concept]
- omipalisib [MeSH Supplementary Concept]
- pegylated 17-hydroxywortmannin [MeSH Supplementary Concept]
- phosphatidyl-3-deoxy-3-aminoethyl-inositol [MeSH Supplementary Concept]
Record concept(s)
- phosphatidylinositol 3-Kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- AGE-1 protein, C elegans [MeSH Supplementary Concept]
- N24 peptide, human [MeSH Supplementary Concept]
- PIK1 protein, dictyostelium discoideum [MeSH Supplementary Concept]
- PIK2 protein, dictyostelium discoideum [MeSH Supplementary Concept]
- PIK3C2A protein, Xenopus [MeSH Supplementary Concept]
- PIK3C2A protein, human [MeSH Supplementary Concept]
- PIK3C2B protein, human [MeSH Supplementary Concept]
- PIK3C2G protein, human [MeSH Supplementary Concept]
- PIK3C3 protein, mouse [MeSH Supplementary Concept]
- PIK3CA protein, human [MeSH Supplementary Concept]
- PIK3CB protein, human [MeSH Supplementary Concept]
- PIK3CD protein, human [MeSH Supplementary Concept]
- PIK3R1 protein, human [MeSH Supplementary Concept]
- PIK3R3 protein, human [MeSH Supplementary Concept]
- PIKFYVE protein, human [MeSH Supplementary Concept]
- PIKI-1 protein, C elegans [MeSH Supplementary Concept]
- Pi3K21B protein, drosophila [MeSH Supplementary Concept]
- Pik3c2a protein, mouse [MeSH Supplementary Concept]
- Pik3c2b protein, mouse [MeSH Supplementary Concept]
- Pik3c2b protein, rat [MeSH Supplementary Concept]
- Pik3c2g protein, mouse [MeSH Supplementary Concept]
- Pik3c2g protein, rat [MeSH Supplementary Concept]
- Pik3ca protein, mouse [MeSH Supplementary Concept]
- Pik3cb protein, mouse [MeSH Supplementary Concept]
- Pik3cb protein, rat [MeSH Supplementary Concept]
- Pik3cd protein, mouse [MeSH Supplementary Concept]
- Pik3cd protein, rat [MeSH Supplementary Concept]
- SMG1 protein, human [MeSH Supplementary Concept]
- TOR protein, arabidopsis [MeSH Supplementary Concept]
- TOR1 protein, S cerevisiae [MeSH Supplementary Concept]
- TOR2 protein, S cerevisiae [MeSH Supplementary Concept]
- phosphoinositol-3 kinase regulatory subunit 2, human [MeSH Supplementary Concept]
- phosphoinositol-3 kinase regulatory subunit 2, mouse [MeSH Supplementary Concept]
- pik3r3 protein, mouse [MeSH Supplementary Concept]
- pikfyve protein, mouse [MeSH Supplementary Concept]
- tor2 protein, S pombe [MeSH Supplementary Concept]
Related MeSH term(s)
- Phosphoinositide-3 Kinase Inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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