Preferred Label : PI3K Inhibitor WX-037;
NCIt related terms : WX-037;
NCIt definition : A phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
PI3K inhibitor WX-037 specifically inhibits PI3K, which prevents the activation of
the PI3K/protein kinase B-mediated signaling pathway. This may result in the inhibition
of both tumor cell growth and survival in PI3K-overexpressing tumor cells. Activation
of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated
PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents.;
UNII : YGE99UD9C2;
CAS number : 1000795-26-5;
Molecule name : WX-037;
NCI Metathesaurus CUI : CL449597;
Origin ID : C107386;
UMLS CUI : C3827067;
Semantic type(s)
- concept_is_in_subset
- has_target
