phosphatidylinositol 3-Kinase

Preferred Label : phosphatidylinositol 3-Kinase;

MeSH definition : A phosphatidylinositol 3-kinase that catalyzes the conversion of 1-phosphatidylinositol into 1-phosphatidylinositol 3-phosphate.;

MeSH synonym : 1-Phosphatidylinositol 3-Kinase; 1 phosphatidylinositol 3 kinase; phosphatidylinositol 3 kinase; Phosphoinositide 3 Kinase; Kinase, Phosphoinositide 3;

MeSH Related Number : EC 2.7.1.137;

Registry Number MeSH : EC 2.7.1.137;

MeSH annotation : PHOSPHATIDYLINOSITOL 3-KINASES is also available;

Wikipedia link : https://en.wikipedia.org/wiki/Phosphatidylinositol 3-kinase;

Is substance : O;

UNII : EC 2.7.1.137;

Details

Origin ID

D058539;

UMLS CUI

C0044602;

ATC code(s)
- Phosphatidylinositol-3-kinase (Pi3K) inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 1-phosphatidylinositol 3-kinase (substance) [SNOMED CT concept]
- PIK3CA wt Allele [NCIt concept]
- PIK3CB wt Allele [NCIt concept]
- PIK3CD wt Allele [NCIt concept]
- PIK3CG wt Allele [NCIt concept]
- Phosphatidylinositol 3-Kinase Regulatory Subunit Gamma [NCIt concept]
- Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Isoform [NCIt concept]
- Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta Isoform [NCIt concept]
- Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform [NCIt concept]
- phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [HGNC gene]
Currated CISMeF NLP mapping
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase [NCIt concept]
Indexing information
- 1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one [MeSH Supplementary Concept]
- 2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo-4H-chromen-8-yl)dibenzo(b,d)thiophen-1-yl)acetamide [MeSH Supplementary Concept]
- 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one [MeSH Supplementary Concept]
- 8-(6-methoxypyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl-3-trifluoromethylphenyl)-1,3-dihydroimidazo(4,5-c)quinolin-2-one [MeSH Supplementary Concept]
- CUDC-907 [MeSH Supplementary Concept]
- ETP-46992 [MeSH Supplementary Concept]
- HS-104 [MeSH Supplementary Concept]
- HS-116 [MeSH Supplementary Concept]
- N-(5-(3-(3-cyanophenyl)imidazo(1,2-a)pyridin-6-yl)pyridin-3-yl)benzenesulfonamide [MeSH Supplementary Concept]
- NVP-BKM120 [MeSH Supplementary Concept]
- SN 30191 [MeSH Supplementary Concept]
- XL147 [MeSH Supplementary Concept]
- XL765 [MeSH Supplementary Concept]
- ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo(1,2-a)pyridine-3-carboxylate [MeSH Supplementary Concept]
Record concept(s)
- phosphatidylinositol 3-Kinase [MeSH concept]
Related MeSH Supplementary Concept(s)
- PIK3R5 protein, human [MeSH Supplementary Concept]
- Pik3r5 protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- Phosphoinositide-3 Kinase Inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 1-phosphatidylinositol 3-kinase (substance) [SNOMED CT concept]
- Phosphatidylinositol-4,5-Bisphosphate 3-Kinase [NCIt concept]

Keyword's position in hierarchy(ies) :

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