Retinoblastoma-Associated Protein

Preferred Label : Retinoblastoma-Associated Protein;

NCIt synonyms : P105-RB; Retinoblastoma Associated Protein; PP110; pRb; Rb; RB Protein; RB1; Retinoblastoma Protein; p110-RB1; Retinoblastoma Suspectibility Protein; RB Transcriptional Corepressor 1;

NCIt definition : Retinoblastoma-associated protein (928 aa, 106 kDa) is encoded by the human RB1 gene. This protein plays a role in the regulation of cell cycle progression.;

NCI Metathesaurus CUI : CL599544;

Details

Origin ID

C17394;

UMLS CUI

C4308074;

Currated CISMeF NLP mapping
- retinoblastoma protein [MeSH Descriptor]
- retinoblastoma protein [MeSH concept]
False automatic mappings
- Retinoblastoma protein [LOINC component]
OMIM relation
- Rb transcriptional corepressor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RB1 protein, human [MeSH Supplementary Concept]
- Retinoblastoma protein [LOINC component]
- retinoblastoma protein [MeSH concept]
- retinoblastoma protein [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Cycle Gene [NCIt concept]
- RB1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Regulatory Protein [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_chemical_classification
- Phosphoprotein [NCIt concept]
gene_product_has_gene_product_variant
- RB1 NP_000312.2:p.F650S [NCIt concept]
- RB1 Protein Variant [NCIt concept]
gene_product_is_biomarker_of
- Retinoblastoma [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- BTG Cell Cycle Regulation Pathway [NCIt concept]
- Bladder Cancer Pathway [NCIt concept]
- Cell Cycle Pathway [NCIt concept]
- Cell Cycle Progression Pathway [NCIt concept]
- Ceramide Signaling Pathway PID [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Cyclin E Degradation Pathway [NCIt concept]
- Cyclin Regulation of Cell Cycle Pathway [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
- E2F1 Degradation Pathway [NCIt concept]
- FOXM1 Transcription Factor Signaling Pathway [NCIt concept]
- Fas Signaling Pathway BioCarta [NCIt concept]
- G1 to S Transition Pathway [NCIt concept]
- G1/S Checkpoint Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- Human Cytomegalovirus Infection Pathway [NCIt concept]
- Interferon Signaling Modulation Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- RB Checkpoint Signaling Pathway [NCIt concept]
- Regulation of Retinoblastoma Protein Pathway [NCIt concept]
- Ribosomal Biogenesis Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- TNFR1 Signaling Pathway [NCIt concept]
- Telomere Pathway [NCIt concept]
- Terc Regulation Pathway [NCIt concept]
- p27 Regulation Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
- p53 Signaling Pathway BioCarta [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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