retinoblastoma protein

Preferred Label : retinoblastoma protein;

MeSH definition : Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.;

MeSH synonym : rb gene product; rb1 gene product; rb protein;

MeSH hyponym : p105-Rb protein; p105 Rb Protein; Retinoblastoma Nuclear Phosphoprotein p105-Rb; Retinoblastoma Nuclear Phosphoprotein p105 Rb;

MeSH annotation : /biosyn /drug eff /physiol /ultrastruct permitted;

Wikipedia link : https://en.wikipedia.org/wiki/Retinoblastoma protein;

Is substance : O;

Details

Origin ID

D016160;

UMLS CUI

C0080113;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Retinoblastoma-Associated Protein [NCIt concept]
Indexing information
- EID1 protein, human [MeSH Supplementary Concept]
- LIN9 protein, human [MeSH Supplementary Concept]
- RRB1 protein, zea mays [MeSH Supplementary Concept]
- RRB2 protein, zea mays [MeSH Supplementary Concept]
Record concept(s)
- p105-Rb protein [MeSH concept]
- retinoblastoma protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- lin-36 protein, C elegans [MeSH Supplementary Concept]
- mat3 protein, chlamydomonas [MeSH Supplementary Concept]
- rbf protein, drosophila [MeSH Supplementary Concept]
- retinoblastoma protein p95 [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- retinoblastoma [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Retinoblastoma protein [LOINC component]
- Retinoblastoma-Associated Protein [NCIt concept]

Keyword's position in hierarchy(ies) :

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