Preferred Label : PRKACA wt Allele;
NCIt synonyms : PKACA; Protein Kinase, cAMP-Dependent, Catalytic, Alpha Gene; Protein Kinase A, C-Alpha Subunit Gene; Protein Kinase, cAMP-Dependent, Alpha Catalytic Subunit Gene; Protein Kinase cAMP-Activated Catalytic Subunit Alpha wt Allele; PPNAD4;
NCIt definition : Human PRKACA wild-type allele is located in the vicinity of 19p13.1 and is approximately
26 kb in length. This allele, which encodes cAMP-dependent protein kinase, alpha-catalytic
subunit protein, plays a role in the phosphorylation of numerous cytoplasmic and nuclear
proteins in response to activation by the signaling molecule cyclic AMP.;
NCIt note : The PRKACA gene produces two RNA transcript variants via alternative splicing which
encode distinct isoforms of the cAMP-dependent protein kinase, alpha-catalytic subunit
protein. Isoform 2 is expressed only in sperm.;
GenBank Accession Number : NM_002730;
Origin ID : C51267;
UMLS CUI : C1709432;
OMIM relation
- Semantic type(s)
- concept_is_in_subset
- gene_found_in_organism
- gene_in_chromosomal_location
- gene_involved_in_pathogenesis_of_disease
- gene_is_element_in_pathway
- gene_plays_role_in_process
