PDPK1 wt Allele

Preferred Label : PDPK1 wt Allele;

NCIt synonyms : PDK1; PRO0461; 3-Phosphoinositide Dependent Protein Kinase 1 wt Allele; PkB Kinase Gene; 3-Phosphoinositide Dependent Protein Kinase-1 Gene;

NCIt definition : Human PDPK1 wild-type allele is located in the vicinity of 16p13.3 and is approximately 63 kb in length. This allele, which encodes 3-phosphoinositide-dependent protein kinase 1 protein, plays a role in the activation of a number of signaling pathways involved in cell proliferation and survival.;

NCIt note : The PDPK1 gene produces three isoforms of 3-phosphoinositide-dependent protein kinase 1 protein via alternative splicing. Isoform 3 of this protein is catalytically inactive.;

GenBank Accession Number : NM_031268;

Détails

Origin ID

C51254;

UMLS CUI

C1709397;

OMIM relation
- 3-phosphoinositide-dependent protein kinase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 16p13.3 [NCIt concept]
gene_is_element_in_pathway
- AKT Signaling Pathway [NCIt concept]
- Aldosterone-Regulated Sodium Reabsorption Pathway [NCIt concept]
- Angiogenesis Pathway [NCIt concept]
- B-Cell Survival Pathway [NCIt concept]
- BAD Regulation Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- Beta-Catenin Accumulation Pathway [NCIt concept]
- CREB Activation Signaling Pathway [NCIt concept]
- CXCR3-Mediated Signaling Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Corticosteroid Cardioprotection Pathway [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- FAS Signaling Pathway PID [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- G1 to S Transition Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Human Cytomegalovirus Infection Pathway [NCIt concept]
- IGF1 Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- Insulin Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Longevity Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- NTRK1/PI3K/PLC-Gamma Signaling Pathway [NCIt concept]
- Neuronal Survival Pathway [NCIt concept]
- Nitric Oxide Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- PI3K/AKT1 Signaling Pathway [NCIt concept]
- PPAR Signaling Pathway [NCIt concept]
- Phosphoinositide Pathway [NCIt concept]
- Phospholipase C Signaling Pathway [NCIt concept]
- Phospholipid Signaling Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Ras Signaling Pathway [NCIt concept]
- Regulation of Apoptosis Pathway [NCIt concept]
- Skeletal Muscle Hypertrophy Pathway [NCIt concept]
- Skeletal Myogenesis Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Trka Receptor Signaling Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
- VEGFR1 and VEGFR2 Signaling [NCIt concept]
- mTOR Signaling Pathway BioCarta [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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