NCIt definition : Human PDPK1 wild-type allele is located in the vicinity of 16p13.3 and is approximately
63 kb in length. This allele, which encodes 3-phosphoinositide-dependent protein kinase
1 protein, plays a role in the activation of a number of signaling pathways involved
in cell proliferation and survival.;
NCIt note : The PDPK1 gene produces three isoforms of 3-phosphoinositide-dependent protein kinase
1 protein via alternative splicing. Isoform 3 of this protein is catalytically inactive.;