DNA Replication Inhibition

Preferred Label : DNA Replication Inhibition;

NCIt definition : DNA Replication Inhibition involves interference with, or restraint of, the activities of biologic molecules or complexes involved in the process by which the two strands of a DNA double helix separate and each strand acts as a template for the synthesis of a complementary strand by specific base pairing.;

Details

Origin ID

C40828;

UMLS CUI

C1511692;

Automatic exact mappings (from CISMeF team)
- negative regulation of DNA replication [GO term]
Semantic type(s)
- Genetic Function [UMLS semantic type]
biological_process_involves_gene_product
- Geminin [NCIt concept]
- Testis-Specific Y-Encoded-Like Protein 2 [NCIt concept]
- Transcription Termination Factor 1 [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- 4'-Iodo-4'-Deoxydoxorubicin [NCIt concept]
- AKR1C3-activated Prodrug AST-3424 [NCIt concept]
- Acylfulvene-derived Prodrug LP-184 [NCIt concept]
- Aminocamptothecin [NCIt concept]
- Aziridinylbenzoquinone RH1 [NCIt concept]
- Belotecan Hydrochloride [NCIt concept]
- Bizelesin [NCIt concept]
- Dianhydrogalactitol [NCIt concept]
- Firtecan Pegol [NCIt concept]
- Gimatecan [NCIt concept]
- Irinotecan [NCIt concept]
- Irinotecan Hydrochloride [NCIt concept]
- Oral Irinotecan Hydrochloride Formulation VAL-413 [NCIt concept]
- Oral Topotecan Hydrochloride [NCIt concept]
- Pegylated Liposomal Irinotecan [NCIt concept]
- Polyethyleneglycol-7-ethyl-10-hydroxycamptothecin DFP-13318 [NCIt concept]
- Pyrazoloacridine [NCIt concept]
- SarCNU [NCIt concept]
- Silatecan AR-67 [NCIt concept]
- Temozolomide [NCIt concept]
- Tenifatecan [NCIt concept]
- Tinostamustine [NCIt concept]
- Tirapazamine [NCIt concept]
- Topoisomerase-II Inhibitor Racemic XK469 [NCIt concept]
- Topotecan Hydrochloride [NCIt concept]
process_involves_gene
- TSPYL2 Gene [NCIt concept]
- TSPYL2 wt Allele [NCIt concept]
- TTF1 Gene [NCIt concept]
- TTF1 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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