TTF1 wt Allele

Preferred Label : TTF1 wt Allele;

NCIt synonyms : Transcription Termination Factor, RNA Polymerase I wt Allele; TTF-I; TTF-1;

NCIt definition : Human TTF1 wild-type allele is located in the vicinity of 9q34.13 and is approximately 31 kb in length. This allele, which encodes transcription termination factor 1 protein, is involved in both transcriptional termination and replication fork arrest.;

NCIt note : TTF1 (GeneID 7270) and NKX2-1 (GeneID 7080) loci share the TTF1 symbol/alias in common. TTF1 is a widely used alternative name for thyroid transcription factor 1 (NKX2-1) conflicting with the official symbol for transcription termination factor, RNA polymerase I (TTF1). (EntrezGene);

GenBank Accession Number : BC050734;

Details

Origin ID

C107623;

UMLS CUI

C3811254;

Automatic exact mappings (from CISMeF team)
- NK2 homeobox 1 [ORDO Gene]
- Nk2 homeobox 1 [OMIM gene]
- Thyroid transcription factor 1 [LOINC component]
- Transcription termination factor, rna polymerase I [OMIM gene]
OMIM relation
- Transcription termination factor, rna polymerase I [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 9q34.13 [NCIt concept]
gene_is_element_in_pathway
- FOXA2 and FOXA3 Transcription Factor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Replication Inhibition [NCIt concept]
- Transcription Termination [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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