Preferred Label : Dianhydrogalactitol;
NCIt synonyms : dianhydrodulcitol; galactitol, 1,2:5,6-dianhydro- (8CI 9CI); Galactitol; 1,2:5, 6-diepoxydulcitol; 1,2,5,6 dianhydrogalactitol; DAG; Bi-functional Alkylating Agent VAL-083; diepoxydulcitol; diepoxygalactitol; 1,2:5,6 dianhydrogalactitol;
NCIt related terms : 1,2:5,6-Dianhydrodulcitol; Dulcitol diepoxide; 1,2:5,6-Diepoxydulcitol; 1,2:5, 6-Dianhydrogalactitol;
NCIt definition : A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol
alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle,
resulting in disruption of DNA function and cell cycle arrest. (NCI04);
UNII : 4S465RYF7M;
CAS number : 23261-20-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 23261-20-3
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G-SRS /a ;
Molecule name : VAL-083;
NSC code : 132313;
Codes from synonyms : NSC0132313;
Origin ID : C425;
UMLS CUI : C0011967;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- chemical_or_drug_has_mechanism_of_action
- chemical_or_drug_has_physiologic_effect
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
