HLA Class II Histocompatibility Antigen, DQ Beta 1 Chain

Preferred Label : HLA Class II Histocompatibility Antigen, DQ Beta 1 Chain;

NCIt synonyms : DC-3 beta chain; HLA Class II Histocompatibility Antigen, DQB1 Beta Chain; MHC Class II Antigen DQB1; HLA Class II Histocompatibility Antigen DQ(1) Beta Chain; HLA Class II Histocompatibility Antigen DQ1 Beta Chain;

NCIt definition : HLA class II histocompatibility antigen, DQ beta 1 chain (261 aa, 30 kDa) is encoded by the human HLA-DQB1 gene. This transmembrane protein is involved in the presentation of peptide antigens on the cell surface.;

NCIt note : HLA class II histocompatibility antigen, DQB1 beta chain has at least two distinct isoforms. These isoforms are HLA class II histocompatibility antigen, DQ(W1.1) beta chain (or DQB1*0501) and HLA class II histocompatibility antigen, DQB1*0602 beta chain (also known as DQ(5) or DC-1).;

Details

Origin ID

C70616;

UMLS CUI

C2348929;

OMIM relation
- Major histocompatibility complex, class II, dq beta-1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HLA-DQB1 Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
- MHC Class II Gene [NCIt concept]
gene_product_expressed_in_tissue
- CD4-Positive T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- HLA Complex [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Allergy Chemokine Network Pathway [NCIt concept]
- Allograft Rejection Pathway [NCIt concept]
- Antigen Dependent B Cell Activation Pathway [NCIt concept]
- Antigen Presentation Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
- Asthma Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- B Lymphocyte Cell Surface Molecule Pathway [NCIt concept]
- Bystander B Cell Activation Pathway [NCIt concept]
- CSK Protein Kinase Activation Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL5 Signaling Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
- TCR Activation Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]
- T-Cell Receptor Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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