HLA-DQB1 wt Allele

Preferred Label : HLA-DQB1 wt Allele;

NCIt synonyms : HLA-DQB1; CELIAC1; IDDM1; Major Histocompatibility Complex, Class II, DQ Beta 1 wt Allele;

NCIt definition : Human HLA-DQB1 wild-type allele is located in the vicinity of 6p21.3 and is approximately 7 kb in length. This allele, which encodes HLA class II histocompatibility antigen, DQ beta 1 chain protein, plays a role in the regulation of antigen presentation.;

NCIt note : The human population has at least 22 alleles of the HLA-DQB1 gene, which potentially encode several isoforms of the major histocompatibility complex, class II, DQ1 beta chain protein. Gene products have been elucidated for two isoforms.;

GenBank Accession Number : NM_002123;

Details

Origin ID

C70615;

UMLS CUI

C2348924;

OMIM relation
- Major histocompatibility complex, class II, dq beta-1 [OMIM gene]
See also inter- (CISMeF)
- HLA-DQB1 [LOINC component]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.3 [NCIt concept]
gene_is_element_in_pathway
- Allergy Chemokine Network Pathway [NCIt concept]
- Allograft Rejection Pathway [NCIt concept]
- Antigen Dependent B Cell Activation Pathway [NCIt concept]
- Antigen Presentation Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
- Asthma Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- B Lymphocyte Cell Surface Molecule Pathway [NCIt concept]
- Bystander B Cell Activation Pathway [NCIt concept]
- CSK Protein Kinase Activation Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL5 Signaling Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
- TCR Activation Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_plays_role_in_process
- Antigen Presentation [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]
- T-Cell Receptor Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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