Interferon Gamma

Preferred Label : Interferon Gamma;

NCIt synonyms : IFN-Gamma; Immune Interferon; Gamma Interferon; IFNG; Interferon-Gamma; Interferon Type II; IFN-g; Gamma-Interferon; Type II Interferon; IFN-II;

NCIt definition : Interferon gamma (166 aa, 19 kDa) is encoded by the human IFNG gene. This protein is involved in antiviral activity, macrophage activation, antiproliferative activity and immunopotentiation.;

Details

Origin ID

C20496;

UMLS CUI

C0021745;

Automatic exact mappings (from CISMeF team)
- Interferon gamma [ICD-11 Extension code]
- Interferon gamma [SMS substance]
- Interferon gamma low [MedDRA LLT]
- Interferon, gamma [OMIM gene]
- Product containing interferon gamma-1b (medicinal product) [SNOMED CT concept]
- interferon gamma [HGNC gene]
- interferon gamma [COVID-19 Thesaurus concept]
- interferon gamma [ORDO Gene]
- interferon type II [COVID-19 Thesaurus concept]
- interferon-gamma receptor binding [GO term]
- interferon-γ [Blood Transfusion thesaurus concept]
False automatic mappings
- Product containing interferon gamma (medicinal product) [SNOMED CT concept]
- interferon gamma (1-39) [MeSH concept]
- interferon gamma (1-39) [MeSH Supplementary Concept]
- interferon-gamma (95-133) [MeSH concept]
- interferon-gamma (95-133) [MeSH Supplementary Concept]
OMIM relation
- Interferon, gamma [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Gamma interferon (substance) [Inactive SNOMED CT concept]
- Interferon gamma [LOINC component]
- Interferon gamma (substance) [SNOMED CT concept]
- Product containing interferon gamma (medicinal product) [SNOMED CT concept]
- gamma interferon [SNOMED Notion]
- interferon gamma [ATC Code]
- interferon-gamma [MeSH concept]
- interferon-gamma [MeSH Descriptor]
Validated automatic mappings to BTNT
- interferon gamma [ATC Code]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IFNG Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Aldesleukin [NCIt concept]
gene_product_expressed_in_tissue
- Natural Killer Cell [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Lymphokine [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_is_biomarker_type
- Disease Marker [NCIt concept]
gene_product_is_element_in_pathway
- 4-1BB-Dependent Immune Response Pathway [NCIt concept]
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- Allograft Rejection Pathway [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Antigen Processing and Presentation Pathway [NCIt concept]
- Autophagy Regulation Pathway [NCIt concept]
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Cytokine Network Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Dendritic Cell Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Granulocyte Adhesion Pathway [NCIt concept]
- IFN Gamma Signaling Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL18 Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- IL27-Mediated Signaling Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Interferon Signaling Modulation Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- NO2-Dependent IL12 Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- PDGFR-alpha Signaling Pathway [NCIt concept]
- Proteasome Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Activation Pathway [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
- Telomerase Regulation Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interferon Signaling Process [NCIt concept]
is_target
- Emapalumab [NCIt concept]
- Zirconium Zr 89-DFO-emapalumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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